ZA971171B - Peptide antagonists of cellular mitogenesis and motogenesis and their therapeutic use. - Google Patents

Peptide antagonists of cellular mitogenesis and motogenesis and their therapeutic use.

Info

Publication number
ZA971171B
ZA971171B ZA9701171A ZA971171A ZA971171B ZA 971171 B ZA971171 B ZA 971171B ZA 9701171 A ZA9701171 A ZA 9701171A ZA 971171 A ZA971171 A ZA 971171A ZA 971171 B ZA971171 B ZA 971171B
Authority
ZA
South Africa
Prior art keywords
motogenesis
therapeutic use
peptide antagonists
mitogenesis
cellular
Prior art date
Application number
ZA9701171A
Other languages
English (en)
Inventor
Carlo Battistini
Patrizia Giordano
Sabrina De Rosa
Fabio Corradi
Paolo Comoglio
Alberto Bardelli
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of ZA971171B publication Critical patent/ZA971171B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA9701171A 1996-02-15 1997-02-12 Peptide antagonists of cellular mitogenesis and motogenesis and their therapeutic use. ZA971171B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9603227.1A GB9603227D0 (en) 1996-02-15 1996-02-15 Peptide antagonists of cellular mitogenesis and motogenesis and their therapeutic use

Publications (1)

Publication Number Publication Date
ZA971171B true ZA971171B (en) 1997-09-03

Family

ID=10788833

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9701171A ZA971171B (en) 1996-02-15 1997-02-12 Peptide antagonists of cellular mitogenesis and motogenesis and their therapeutic use.

Country Status (21)

Country Link
US (1) US6245742B1 (no)
EP (1) EP0821696B1 (no)
JP (1) JPH11504658A (no)
KR (1) KR19990007783A (no)
CN (1) CN1185785A (no)
AR (1) AR005808A1 (no)
AT (1) ATE266041T1 (no)
AU (1) AU1768297A (no)
BR (1) BR9702084A (no)
CA (1) CA2218378A1 (no)
DE (1) DE69728938D1 (no)
EA (1) EA199700318A1 (no)
GB (1) GB9603227D0 (no)
HU (1) HUP9900661A3 (no)
IL (1) IL121853A0 (no)
MX (1) MX9707771A (no)
NO (1) NO974750L (no)
NZ (1) NZ328895A (no)
PL (1) PL322779A1 (no)
WO (1) WO1997030079A1 (no)
ZA (1) ZA971171B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2787793B1 (fr) * 1998-12-24 2001-03-23 Inst Nat Sante Rech Med Composes pseudopeptidiques dotes d'une activite inhibitrice a l'egard des voies activees par les proteines a activite tyrosine kinase et les compositions pharmaceutiques les contenant
US20020055463A1 (en) * 1998-12-24 2002-05-09 Christiane Garbay Pseudopeptide compounds having an inhibiting activity with respect to paths activated by proteins with active tyrosine kinase activity and pharmaceutical compositions containing same
FR2793796A1 (fr) * 1999-04-14 2000-11-24 Hoechst Marion Roussel Inc Nouveaux derives d'imidazoles, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2796381A1 (fr) * 1999-07-12 2001-01-19 Hoechst Marion Roussel Inc Derives bicycliques de thioazepine ou de caprolactame, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
US20040191926A1 (en) * 2001-09-26 2004-09-30 Zhong-Yin Zhang Ptp1b inhibitors and ligands
WO2005114197A2 (en) * 2004-04-15 2005-12-01 Albert Einstein College Of Medicine Of Yeshiva University Activity-based probes for protein tyrosine phosphatases
WO2008104063A1 (en) 2007-02-26 2008-09-04 Stemcell Technologies Inc. Method of reducing curvature in a meniscus of liquid medium
CA2678570C (en) 2008-09-12 2016-08-16 Stemcell Technologies Inc. Cell culture vessels for meniscus reduction with aqueous solutions
CN103387602B (zh) * 2012-05-09 2018-07-06 中国科学院上海药物研究所 一种新型开链四肽类似物及其制备方法和用途
US10537891B2 (en) 2013-01-10 2020-01-21 Stemcell Technologies Inc. Meniscus reducing member
WO2014107811A1 (en) 2013-01-10 2014-07-17 Stemcell Technologies Inc. Meniscus reducing member

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5801149A (en) * 1991-06-19 1998-09-01 Joslin D-Abetes Center, Inc. Inhibition of signal transduction molecules
US5739278A (en) * 1993-05-10 1998-04-14 University Of Washington Compositions for protein tyrosine phosphatases
CN1056153C (zh) * 1993-06-30 2000-09-06 法玛西雅厄普约翰公司 有丝分裂发生和运动发生的肽抑制物
WO1996023813A1 (en) * 1995-02-01 1996-08-08 Affymax Technologies N.V. Peptides and compounds that bind to sh2 domains
GB9516842D0 (en) * 1995-08-17 1995-10-18 Ciba Geigy Ag Various acylated oligopeptides
GB9517060D0 (en) * 1995-08-17 1995-10-25 Ciba Geigy Ag Acylated oligopeptide derivatives

Also Published As

Publication number Publication date
BR9702084A (pt) 1999-07-20
CA2218378A1 (en) 1997-08-21
EP0821696A1 (en) 1998-02-04
GB9603227D0 (en) 1996-04-17
EP0821696B1 (en) 2004-05-06
PL322779A1 (en) 1998-02-16
WO1997030079A1 (en) 1997-08-21
CN1185785A (zh) 1998-06-24
EA199700318A1 (ru) 1998-04-30
AR005808A1 (es) 1999-07-14
HUP9900661A2 (hu) 1999-08-30
DE69728938D1 (de) 2004-06-09
ATE266041T1 (de) 2004-05-15
US6245742B1 (en) 2001-06-12
AU1768297A (en) 1997-09-02
JPH11504658A (ja) 1999-04-27
IL121853A0 (en) 1998-02-22
NO974750D0 (no) 1997-10-14
MX9707771A (es) 1997-12-31
NZ328895A (en) 1999-03-29
HUP9900661A3 (en) 2000-03-28
KR19990007783A (ko) 1999-01-25
NO974750L (no) 1997-12-10

Similar Documents

Publication Publication Date Title
EP0880356A4 (en) ANTIMICROBIAL PEPTIDES AND METHODS OF USE THEREOF
SG91796A1 (en) N-(4-aryl-thiazol-2-yl)-sulphonamide derivatives and their use
ZA971171B (en) Peptide antagonists of cellular mitogenesis and motogenesis and their therapeutic use.
GB9712761D0 (en) Quinolines and their therapeutic use
HUP9800146A3 (en) Thalidomide-derivatives and use of them
GB9620777D0 (en) Therapeutic use
AU3116697A (en) Human interleukin-1j and antagonists thereof
ZA986047B (en) 6-pyrrolidin-2-ylpyrindines their preparation and their therapeutic application
GB9615435D0 (en) Spray-dried product and its therapeutic use
GB9616504D0 (en) Therapeutic product and its use
PL321172A1 (en) Rest and rehabilitation bed
GB9621886D0 (en) Microparticles and their therapeutic use
GB9621826D0 (en) Microparticles and their therapeutic use
AU130933S (en) Set of adjustable lounges
GB9714297D0 (en) Benzofurans and their therapeutic use
GB9725637D0 (en) Benzofurans and their therapeutic use
TW308065U (en) Dual-purpose massage chair
ZA9710000B (en) Quinolines and their therapeutic use
GB9616823D0 (en) Therapeutic product and its use
GB9616508D0 (en) Therapeutic product and its use
GB9616507D0 (en) Therapeutic product and its use
GB9616505D0 (en) Therapeutic product and its use
GB9616503D0 (en) Therapeutic product and its use
GB9616551D0 (en) Therapeutic product and its use
GB9616550D0 (en) Therapeutic product and its use