ZA9710141B - Process for the preparation of salts and esters of clauvulanic acid. - Google Patents

Process for the preparation of salts and esters of clauvulanic acid.

Info

Publication number
ZA9710141B
ZA9710141B ZA9710141A ZA9710141A ZA9710141B ZA 9710141 B ZA9710141 B ZA 9710141B ZA 9710141 A ZA9710141 A ZA 9710141A ZA 9710141 A ZA9710141 A ZA 9710141A ZA 9710141 B ZA9710141 B ZA 9710141B
Authority
ZA
South Africa
Prior art keywords
esters
salts
preparation
clauvulanic
acid
Prior art date
Application number
ZA9710141A
Other languages
English (en)
Inventor
Johannes Booij
Antonius Van Den Heuvel
Original Assignee
Gist Brocades Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Bv filed Critical Gist Brocades Bv
Publication of ZA9710141B publication Critical patent/ZA9710141B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA9710141A 1996-11-11 1997-11-11 Process for the preparation of salts and esters of clauvulanic acid. ZA9710141B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96203117 1996-11-11

Publications (1)

Publication Number Publication Date
ZA9710141B true ZA9710141B (en) 1998-06-25

Family

ID=8224563

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9710141A ZA9710141B (en) 1996-11-11 1997-11-11 Process for the preparation of salts and esters of clauvulanic acid.

Country Status (11)

Country Link
EP (1) EP0937084A1 (xx)
JP (1) JP2001503763A (xx)
CN (1) CN1238776A (xx)
AU (1) AU5551698A (xx)
BR (1) BR9713339A (xx)
CA (1) CA2271847A1 (xx)
NO (1) NO992225D0 (xx)
PL (1) PL333247A1 (xx)
TR (1) TR199901631T2 (xx)
WO (1) WO1998021212A1 (xx)
ZA (1) ZA9710141B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT400033B (de) 1992-03-10 1995-09-25 Biochemie Gmbh Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben
SI9500134B (sl) * 1995-04-20 2004-04-30 Lek, Postopek za pripravo čistih alkalijskih soli klavulanske kisline
AT403375B (de) * 1995-11-15 1998-01-26 Biochemie Gmbh Verfahren zur fällung von alkalisalzen der clavulansäure
EP1095046A1 (en) * 1998-07-16 2001-05-02 Dsm N.V. Improved process for the preparation of salts and esters of clavulanic acid
WO2000041478A2 (en) * 1999-04-01 2000-07-20 Dsm N.V. Agglomerates by crystallisation
ES2225524T5 (es) * 2000-05-13 2009-03-01 Smithkline Beecham Plc Procedimiento para la purificacion de una sal de acido clavulanico.
WO2008065160A1 (en) * 2006-12-01 2008-06-05 Dsm Ip Assets B.V. Process for the production of clavulanic acid

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9300296B (sl) * 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
KR100200239B1 (ko) * 1992-10-21 1999-06-15 김충환 클라불란산 칼륨염의 제조방법
GB9305565D0 (en) * 1993-03-18 1993-05-05 Smithkline Beecham Plc Novel compounds and processes
SI9400107A (en) * 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en) * 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts
SI9500074A (en) * 1995-03-10 1996-10-31 Lek Tovarna Farmacevtskih Process for preparation of alkani salts of clavulanic acid.
SI9500134B (sl) * 1995-04-20 2004-04-30 Lek, Postopek za pripravo čistih alkalijskih soli klavulanske kisline
KR100200242B1 (ko) * 1995-05-16 1999-06-15 김충환 클라불란산염의 제조 방법

Also Published As

Publication number Publication date
PL333247A1 (en) 1999-11-22
EP0937084A1 (en) 1999-08-25
CN1238776A (zh) 1999-12-15
BR9713339A (pt) 2000-05-09
WO1998021212A1 (en) 1998-05-22
CA2271847A1 (en) 1998-05-22
JP2001503763A (ja) 2001-03-21
NO992225L (no) 1999-05-07
AU5551698A (en) 1998-06-03
TR199901631T2 (xx) 1999-09-21
NO992225D0 (no) 1999-05-07

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