AU5551698A - Process for the preparation of salts and esters of clavulanic acid - Google Patents

Process for the preparation of salts and esters of clavulanic acid

Info

Publication number
AU5551698A
AU5551698A AU55516/98A AU5551698A AU5551698A AU 5551698 A AU5551698 A AU 5551698A AU 55516/98 A AU55516/98 A AU 55516/98A AU 5551698 A AU5551698 A AU 5551698A AU 5551698 A AU5551698 A AU 5551698A
Authority
AU
Australia
Prior art keywords
esters
salts
preparation
clavulanic acid
clavulanic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU55516/98A
Inventor
Johannes Booij
Antonius Van Den Heuvel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM Delft BV
Original Assignee
Gist Brocades BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades BV filed Critical Gist Brocades BV
Publication of AU5551698A publication Critical patent/AU5551698A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU55516/98A 1996-11-11 1997-11-10 Process for the preparation of salts and esters of clavulanic acid Abandoned AU5551698A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP96203117 1996-11-11
EP96203117 1996-11-11
PCT/EP1997/006263 WO1998021212A1 (en) 1996-11-11 1997-11-10 Process for the preparation of salts and esters of clavulanic acid

Publications (1)

Publication Number Publication Date
AU5551698A true AU5551698A (en) 1998-06-03

Family

ID=8224563

Family Applications (1)

Application Number Title Priority Date Filing Date
AU55516/98A Abandoned AU5551698A (en) 1996-11-11 1997-11-10 Process for the preparation of salts and esters of clavulanic acid

Country Status (11)

Country Link
EP (1) EP0937084A1 (en)
JP (1) JP2001503763A (en)
CN (1) CN1238776A (en)
AU (1) AU5551698A (en)
BR (1) BR9713339A (en)
CA (1) CA2271847A1 (en)
NO (1) NO992225L (en)
PL (1) PL333247A1 (en)
TR (1) TR199901631T2 (en)
WO (1) WO1998021212A1 (en)
ZA (1) ZA9710141B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT400033B (en) 1992-03-10 1995-09-25 Biochemie Gmbh NEW METHOD FOR ISOLATING AND PURIFYING CLAVULANIC ACID AND FOR PRODUCING PHARMACOLOGICALLY COMPATIBLE SALTS THEREOF
SI9500134B (en) * 1995-04-20 2004-04-30 Lek, Preparation procedure of pure alkali salts of clavulanic acid
AT403375B (en) * 1995-11-15 1998-01-26 Biochemie Gmbh METHOD FOR FILLING ALKALINE SALTS OF CLAVULANIC ACID
EP1095046A1 (en) * 1998-07-16 2001-05-02 Dsm N.V. Improved process for the preparation of salts and esters of clavulanic acid
SI1165049T2 (en) 1999-04-01 2011-11-30 Dsm Ip Assets Bv Agglomerates by crystallisation
DK1284978T4 (en) * 2000-05-13 2009-01-05 Smithkline Beecham Plc Process for purifying a salt of clavulanic acid
WO2008065160A1 (en) * 2006-12-01 2008-06-05 Dsm Ip Assets B.V. Process for the production of clavulanic acid

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9300296B (en) * 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Process and intermediates for the preparation of clavulanic acid
KR100200239B1 (en) * 1992-10-21 1999-06-15 김충환 Process for preparing salts of clavulanic acid
GB9305565D0 (en) * 1993-03-18 1993-05-05 Smithkline Beecham Plc Novel compounds and processes
SI9400107A (en) * 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en) * 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts
SI9500074A (en) * 1995-03-10 1996-10-31 Lek Tovarna Farmacevtskih Process for preparation of alkani salts of clavulanic acid.
SI9500134B (en) * 1995-04-20 2004-04-30 Lek, Preparation procedure of pure alkali salts of clavulanic acid
KR100200242B1 (en) * 1995-05-16 1999-06-15 김충환 Process for preparing clavulanic acid salt

Also Published As

Publication number Publication date
ZA9710141B (en) 1998-06-25
NO992225D0 (en) 1999-05-07
CA2271847A1 (en) 1998-05-22
TR199901631T2 (en) 1999-09-21
BR9713339A (en) 2000-05-09
NO992225L (en) 1999-05-07
WO1998021212A1 (en) 1998-05-22
CN1238776A (en) 1999-12-15
EP0937084A1 (en) 1999-08-25
JP2001503763A (en) 2001-03-21
PL333247A1 (en) 1999-11-22

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