NO992225L - Process for the preparation of salts and esters of clavulanic acid - Google Patents
Process for the preparation of salts and esters of clavulanic acidInfo
- Publication number
- NO992225L NO992225L NO992225A NO992225A NO992225L NO 992225 L NO992225 L NO 992225L NO 992225 A NO992225 A NO 992225A NO 992225 A NO992225 A NO 992225A NO 992225 L NO992225 L NO 992225L
- Authority
- NO
- Norway
- Prior art keywords
- esters
- preparation
- clavulanic acid
- salts
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
En forbedret fremgangsmåte for fremstillingen av farmasøytisk akseptable alkalimetallsalter eller estere av klavulansyre er blitt tilveiebrakt. Videre er det også blitt tilveiebrakt kaliumklavulanat med et ekstremt lavt amininnhold og farmasøytiske sammensetninger som inneholder det samme.An improved process for the preparation of pharmaceutically acceptable alkali metal salts or esters of clavulanic acid has been provided. Furthermore, potassium clavulanate with an extremely low amine content and pharmaceutical compositions containing the same has also been provided.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP96203117 | 1996-11-11 | ||
PCT/EP1997/006263 WO1998021212A1 (en) | 1996-11-11 | 1997-11-10 | Process for the preparation of salts and esters of clavulanic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
NO992225D0 NO992225D0 (en) | 1999-05-07 |
NO992225L true NO992225L (en) | 1999-05-07 |
Family
ID=8224563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO992225A NO992225L (en) | 1996-11-11 | 1999-05-07 | Process for the preparation of salts and esters of clavulanic acid |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0937084A1 (en) |
JP (1) | JP2001503763A (en) |
CN (1) | CN1238776A (en) |
AU (1) | AU5551698A (en) |
BR (1) | BR9713339A (en) |
CA (1) | CA2271847A1 (en) |
NO (1) | NO992225L (en) |
PL (1) | PL333247A1 (en) |
TR (1) | TR199901631T2 (en) |
WO (1) | WO1998021212A1 (en) |
ZA (1) | ZA9710141B (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT400033B (en) | 1992-03-10 | 1995-09-25 | Biochemie Gmbh | NEW METHOD FOR ISOLATING AND PURIFYING CLAVULANIC ACID AND FOR PRODUCING PHARMACOLOGICALLY COMPATIBLE SALTS THEREOF |
SI9500134B (en) * | 1995-04-20 | 2004-04-30 | Lek, | Preparation procedure of pure alkali salts of clavulanic acid |
AT403375B (en) * | 1995-11-15 | 1998-01-26 | Biochemie Gmbh | METHOD FOR FILLING ALKALINE SALTS OF CLAVULANIC ACID |
CN1312814A (en) * | 1998-07-16 | 2001-09-12 | Dsm公司 | Improved process for preparing salts and esters of clavulanic acid |
CN1209099C (en) | 1999-04-01 | 2005-07-06 | Dsm公司 | Agglomerates by crystallisation |
EP1284978B2 (en) | 2000-05-13 | 2008-09-10 | Smithkline Beecham Plc | Process for the purification of a salt of clavulanic acid |
US20100055749A1 (en) * | 2006-12-01 | 2010-03-04 | Van Der Does Thomas | Process for the production of clavulanic acid |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI9300296B (en) * | 1992-06-11 | 1998-06-30 | Smithkline Beecham P.L.C. | Process and intermediates for the preparation of clavulanic acid |
KR100200239B1 (en) * | 1992-10-21 | 1999-06-15 | 김충환 | Process for preparing salts of clavulanic acid |
GB9305565D0 (en) * | 1993-03-18 | 1993-05-05 | Smithkline Beecham Plc | Novel compounds and processes |
SI9400107A (en) * | 1994-03-02 | 1995-10-31 | Lek Tovarna Farmacevtskih | New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804. |
GB9426261D0 (en) * | 1994-12-24 | 1995-02-22 | Spurcourt Ltd | Clavulanic acid salts |
SI9500074A (en) * | 1995-03-10 | 1996-10-31 | Lek Tovarna Farmacevtskih | Process for preparation of alkani salts of clavulanic acid. |
SI9500134B (en) * | 1995-04-20 | 2004-04-30 | Lek, | Preparation procedure of pure alkali salts of clavulanic acid |
KR100200242B1 (en) * | 1995-05-16 | 1999-06-15 | 김충환 | Process for preparing clavulanic acid salt |
-
1997
- 1997-11-10 CA CA002271847A patent/CA2271847A1/en not_active Abandoned
- 1997-11-10 CN CN97180163A patent/CN1238776A/en active Pending
- 1997-11-10 WO PCT/EP1997/006263 patent/WO1998021212A1/en not_active Application Discontinuation
- 1997-11-10 EP EP97951881A patent/EP0937084A1/en not_active Withdrawn
- 1997-11-10 JP JP52216798A patent/JP2001503763A/en active Pending
- 1997-11-10 AU AU55516/98A patent/AU5551698A/en not_active Abandoned
- 1997-11-10 PL PL97333247A patent/PL333247A1/en unknown
- 1997-11-10 BR BR9713339-6A patent/BR9713339A/en not_active Application Discontinuation
- 1997-11-10 TR TR1999/01631T patent/TR199901631T2/en unknown
- 1997-11-11 ZA ZA9710141A patent/ZA9710141B/en unknown
-
1999
- 1999-05-07 NO NO992225A patent/NO992225L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BR9713339A (en) | 2000-05-09 |
WO1998021212A1 (en) | 1998-05-22 |
NO992225D0 (en) | 1999-05-07 |
EP0937084A1 (en) | 1999-08-25 |
PL333247A1 (en) | 1999-11-22 |
AU5551698A (en) | 1998-06-03 |
TR199901631T2 (en) | 1999-09-21 |
JP2001503763A (en) | 2001-03-21 |
ZA9710141B (en) | 1998-06-25 |
CA2271847A1 (en) | 1998-05-22 |
CN1238776A (en) | 1999-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |