ZA969945B - Long-lasting release nifedipine preparation - Google Patents

Long-lasting release nifedipine preparation

Info

Publication number
ZA969945B
ZA969945B ZA969945A ZA969945A ZA969945B ZA 969945 B ZA969945 B ZA 969945B ZA 969945 A ZA969945 A ZA 969945A ZA 969945 A ZA969945 A ZA 969945A ZA 969945 B ZA969945 B ZA 969945B
Authority
ZA
South Africa
Prior art keywords
hours
long
nifedipine
lasting release
dissolution test
Prior art date
Application number
ZA969945A
Other languages
English (en)
Inventor
Takaaki Nishioka
Kenji Kuratani
Haruo Kanasaki
Helmut Luchtenberg
Ulrich Tenter
Andreas Ohm
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA969945B publication Critical patent/ZA969945B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
ZA969945A 1995-11-28 1996-11-27 Long-lasting release nifedipine preparation ZA969945B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP33121795A JP3220373B2 (ja) 1995-11-28 1995-11-28 持続性ニフエジピン製剤

Publications (1)

Publication Number Publication Date
ZA969945B true ZA969945B (en) 1997-06-23

Family

ID=18241212

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA969945A ZA969945B (en) 1995-11-28 1996-11-27 Long-lasting release nifedipine preparation

Country Status (14)

Country Link
US (1) US5861173A (de)
EP (1) EP0776660B1 (de)
JP (1) JP3220373B2 (de)
KR (1) KR970025607A (de)
AT (1) ATE220898T1 (de)
AU (1) AU709887B2 (de)
CA (1) CA2191178C (de)
DE (1) DE69622510T2 (de)
ES (1) ES2180683T3 (de)
IL (1) IL119684A (de)
MX (1) MX9605646A (de)
NZ (1) NZ299818A (de)
SG (1) SG48492A1 (de)
ZA (1) ZA969945B (de)

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IN190974B (de) * 1999-09-10 2003-09-06 Ranbaxy Lab Ltd
JP2003521507A (ja) 2000-02-04 2003-07-15 ディポメド，インコーポレイティド ゼロ次薬物放出に接近するシェル−コア剤形
JP4637338B2 (ja) * 2000-09-22 2011-02-23 大塚製薬株式会社 シロスタゾール有核錠
SE0004671D0 (sv) 2000-12-15 2000-12-15 Amarin Dev Ab Pharmaceutical formulation
KR100685945B1 (ko) 2000-12-29 2007-02-23 엘지.필립스 엘시디 주식회사 액정표시장치 및 그 제조방법
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
US20050175687A1 (en) * 2001-01-30 2005-08-11 Mcallister Stephen M. Pharmaceutical formulations
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US6987123B2 (en) 2001-07-26 2006-01-17 Cadila Healthcare Limited Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine
JP4817562B2 (ja) * 2001-09-26 2011-11-16 東和薬品株式会社 長時間持続型ニフエジピン有核錠
BR0212950A (pt) * 2001-09-28 2004-10-26 Mcneil Ppc Inc Formas de dosagens compósitas tendo uma porção inserida
CA2409552A1 (en) 2001-10-25 2003-04-25 Depomed, Inc. Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US20030104052A1 (en) * 2001-10-25 2003-06-05 Bret Berner Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
US20030152622A1 (en) * 2001-10-25 2003-08-14 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral diuretic
US6682759B2 (en) 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
WO2003080057A1 (fr) * 2002-03-27 2003-10-02 Bayer Aktiengesellschaft Comprime-noyau de taille reduite contenant de la nifedipine
DE60228939D1 (de) * 2002-05-21 2008-10-30 Watson Lab Inc Pharmazeutische Zusammensetzung mit verzögerter Freisetzung
JP4563642B2 (ja) * 2002-05-31 2010-10-13 ワトソン ラボラトリーズ、インコーポレイテッド 医薬製剤
JP4933033B2 (ja) * 2003-03-17 2012-05-16 武田薬品工業株式会社 放出制御組成物
CA2519208A1 (en) * 2003-03-17 2004-09-30 Takeda Pharmaceutical Company Limited Controlled release composition
KR101192722B1 (ko) 2003-04-24 2012-10-18 자고텍 아게 정해진 핵 위치를 가지는 서방성 정제
US20040219210A1 (en) * 2003-05-01 2004-11-04 Jian-Hwa Guo Controlled release solid dosage nifedipine formulations
US20040241234A1 (en) * 2003-06-02 2004-12-02 Alpharma, Inc. Controlled release press-coated formulations of water-soluble active agents
US20050013863A1 (en) 2003-07-18 2005-01-20 Depomed, Inc., A Corporation Of The State Of California Dual drug dosage forms with improved separation of drugs
TW200526274A (en) 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
US20060024368A1 (en) * 2004-07-30 2006-02-02 Reza Fassihi Compressed composite delivery system for release-rate modulation of bioactives
US7470293B2 (en) * 2004-10-29 2008-12-30 Idatech, Llc Feedstock delivery systems, fuel processing systems, and hydrogen generation assemblies including the same
US8673352B2 (en) * 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
DE102005031577A1 (de) 2005-07-06 2007-01-11 Bayer Healthcare Ag Pharmazeutische Darreichungsformen enthaltend eine Wirkstoffkombination von Nifedipin und/oder Nisoldipin und einem Angiotensin-II Antagonisten
US8637078B2 (en) * 2005-11-24 2014-01-28 Boehringer Ingelheim International Gmbh Bilayer tablet comprising telmisartan and diuretic
KR100774250B1 (ko) 2006-04-14 2007-11-07 넨시스(주) 1,4-디히드로피리딘 유도체 용출 제어형 과립제, 이의 정제및 이의 제조방법
SI2049123T2 (sl) 2006-08-03 2016-10-28 Horizon Pharma Ag Zdravljenje revmatoznih bolezni z zadržanim sproščanjem glukokortikoida
MX2009012974A (es) * 2007-06-11 2010-01-18 Appleton Paper Inc Agente benefico que contiene una particula de suministro.
WO2009028598A1 (ja) 2007-08-31 2009-03-05 Daiichi Sankyo Company, Limited 徐放性製剤及びその製造方法
WO2009054550A1 (en) * 2007-10-25 2009-04-30 Bayer Yakuhin, Ltd. Nifedipine-containing press coated tablet and method of preparing the same
US20090285889A1 (en) * 2008-05-14 2009-11-19 Capricom Pharma Inc. Modified release formulations of dihydropyridine compounds and methods of making same
DE102008059206A1 (de) 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum
CA2802831C (en) * 2010-06-16 2018-11-20 Teijin Pharma Limited Controlled release coat-core tablet
JP6504163B2 (ja) * 2014-06-02 2019-04-24 ニプロ株式会社 レーザー印刷用錠剤及びその製造方法
JP6925970B2 (ja) * 2015-02-09 2021-08-25 エンテラ バイオ エルティーディー． 副甲状腺機能低下症の治療
TW201729814A (zh) 2015-12-24 2017-09-01 武田藥品工業股份有限公司 固形製劑
CN115192538B (zh) * 2022-08-02 2023-09-15 沈阳信康药物研究有限公司 一种压制包衣型硝苯地平缓释片及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3033919A1 (de) 1980-09-09 1982-04-22 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung
DE3720757A1 (de) * 1987-06-24 1989-01-05 Bayer Ag Dhp-manteltablette
NO883326L (no) * 1987-08-11 1989-02-13 Bayer Ag Dhp-retard-tilberedning.
DE3814532A1 (de) * 1988-04-29 1989-11-09 Bayer Ag Dhp-retard-zubereitung
HU203041B (en) * 1989-03-14 1991-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin

Also Published As

Publication number Publication date
JP3220373B2 (ja) 2001-10-22
AU709887B2 (en) 1999-09-09
ATE220898T1 (de) 2002-08-15
AU7196096A (en) 1997-06-05
NZ299818A (en) 1998-08-26
ES2180683T3 (es) 2003-02-16
SG48492A1 (en) 1998-04-17
EP0776660A3 (de) 1998-01-21
JPH09143073A (ja) 1997-06-03
KR970025607A (ko) 1997-06-24
DE69622510D1 (de) 2002-08-29
CA2191178C (en) 2005-10-04
IL119684A0 (en) 1997-02-18
DE69622510T2 (de) 2002-11-07
IL119684A (en) 2000-09-28
US5861173A (en) 1999-01-19
CA2191178A1 (en) 1997-05-29
EP0776660B1 (de) 2002-07-24
EP0776660A2 (de) 1997-06-04
MX9605646A (es) 1997-06-28

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