ZA968732B - Amino substituted pyrimidines and triazines. - Google Patents
Amino substituted pyrimidines and triazines.Info
- Publication number
- ZA968732B ZA968732B ZA9608732A ZA968732A ZA968732B ZA 968732 B ZA968732 B ZA 968732B ZA 9608732 A ZA9608732 A ZA 9608732A ZA 968732 A ZA968732 A ZA 968732A ZA 968732 B ZA968732 B ZA 968732B
- Authority
- ZA
- South Africa
- Prior art keywords
- triazines
- amino substituted
- substituted pyrimidines
- pyrimidines
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/14—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US568795P | 1995-10-17 | 1995-10-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA968732B true ZA968732B (en) | 1998-04-16 |
Family
ID=21717189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9608732A ZA968732B (en) | 1995-10-17 | 1996-10-16 | Amino substituted pyrimidines and triazines. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6288060B1 (ko) |
| EP (1) | EP0863882B1 (ko) |
| JP (1) | JPH11513678A (ko) |
| KR (1) | KR19990045744A (ko) |
| AR (1) | AR004221A1 (ko) |
| AT (1) | ATE212987T1 (ko) |
| AU (1) | AU703096B2 (ko) |
| CA (1) | CA2229710A1 (ko) |
| DE (1) | DE69619125T2 (ko) |
| DK (1) | DK0863882T3 (ko) |
| ES (1) | ES2172681T3 (ko) |
| MY (1) | MY113945A (ko) |
| NO (1) | NO310771B1 (ko) |
| NZ (1) | NZ320227A (ko) |
| PT (1) | PT863882E (ko) |
| TW (1) | TW378206B (ko) |
| WO (1) | WO1997014684A1 (ko) |
| ZA (1) | ZA968732B (ko) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6191131B1 (en) | 1997-07-23 | 2001-02-20 | Dupont Pharmaceuticals Company | Azolo triazines and pyrimidines |
| US6313124B1 (en) | 1997-07-23 | 2001-11-06 | Dupont Pharmaceuticals Company | Tetrazine bicyclic compounds |
| US6060478A (en) * | 1996-07-24 | 2000-05-09 | Dupont Pharmaceuticals | Azolo triazines and pyrimidines |
| US6124289A (en) * | 1996-07-24 | 2000-09-26 | Dupont Pharmaceuticals Co. | Azolo triazines and pyrimidines |
| US7094782B1 (en) | 1996-07-24 | 2006-08-22 | Bristol-Myers Squibb Company | Azolo triazines and pyrimidines |
| DE19837387A1 (de) * | 1998-08-18 | 2000-02-24 | Aventis Res & Tech Gmbh & Co | 3'-Desoxypentopyranosyl-Nucleinsäure, ihre Herstellung und Verwendung |
| AU3357700A (en) * | 1999-02-16 | 2000-09-04 | E.I. Du Pont De Nemours And Company | Phenoxypyrimidine insecticides and acaricides |
| US6432989B1 (en) | 1999-08-27 | 2002-08-13 | Pfizer Inc | Use of CRF antagonists to treat circadian rhythm disorders |
| US6506762B1 (en) | 1999-09-30 | 2003-01-14 | Neurogen Corporation | Certain alkylene diamine-substituted heterocycles |
| US6525067B1 (en) * | 1999-11-23 | 2003-02-25 | Pfizer Inc | Substituted heterocyclic derivatives |
| WO2001062718A1 (fr) * | 2000-02-25 | 2001-08-30 | Japan Tobacco, Inc. | Dérivé de benzamide et utilisation de celui-ci |
| CA2416248A1 (en) | 2000-07-18 | 2002-01-24 | Neurogen Corporation | 5-substituted 2-aryl-4-pyrimidinones |
| ATE283844T1 (de) | 2000-09-19 | 2004-12-15 | Sumitomo Chemical Co | Pyrimidinverbindungen und deren verwendung als pestizide |
| HUP0303038A2 (hu) | 2000-09-21 | 2003-12-29 | Bristol-Myers Squibb Co. | Szubsztituált azolszármazékok mint kortikotropin releasing faktor inhibitorok, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk |
| US20030055249A1 (en) * | 2001-07-17 | 2003-03-20 | Fick David B. | Synthesis and methods of use of pyrimidine analogues and derivatives |
| US6872827B2 (en) * | 2002-04-26 | 2005-03-29 | Chembridge Research Laboratories, Inc. | Somatostatin analogue compounds |
| EP1626725A4 (en) * | 2003-05-29 | 2006-06-14 | Synta Pharmaceuticals Corp | Heterocyclic compounds for the prevention and treatment of disorders associated with excessive bone formation |
| US20060024661A1 (en) * | 2003-07-30 | 2006-02-02 | The Regents Of The University Of California | Modulation of CRF potentiation of NMDA receptor currents via CRF receptor 2 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2595697B1 (fr) | 1986-03-13 | 1988-07-08 | Rousselot Cie | Derives de benzyl-pyrimidine, leur procede de preparation ainsi que les compositions en contenant |
| FR2692893B1 (fr) | 1992-06-24 | 1994-09-02 | Sanofi Elf | Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. |
| WO1995010506A1 (en) * | 1993-10-12 | 1995-04-20 | The Du Pont Merck Pharmaceutical Company | 1n-alkyl-n-arylpyrimidinamines and derivatives thereof |
| TW574214B (en) * | 1994-06-08 | 2004-02-01 | Pfizer | Corticotropin releasing factor antagonists |
-
1996
- 1996-10-15 PT PT96934690T patent/PT863882E/pt unknown
- 1996-10-15 JP JP9515515A patent/JPH11513678A/ja not_active Ceased
- 1996-10-15 DK DK96934690T patent/DK0863882T3/da active
- 1996-10-15 KR KR1019980701986A patent/KR19990045744A/ko active IP Right Grant
- 1996-10-15 DE DE69619125T patent/DE69619125T2/de not_active Expired - Fee Related
- 1996-10-15 WO PCT/EP1996/004478 patent/WO1997014684A1/en active IP Right Grant
- 1996-10-15 ES ES96934690T patent/ES2172681T3/es not_active Expired - Lifetime
- 1996-10-15 NZ NZ320227A patent/NZ320227A/en unknown
- 1996-10-15 AU AU72929/96A patent/AU703096B2/en not_active Ceased
- 1996-10-15 AT AT96934690T patent/ATE212987T1/de not_active IP Right Cessation
- 1996-10-15 CA CA002229710A patent/CA2229710A1/en not_active Abandoned
- 1996-10-15 US US09/051,672 patent/US6288060B1/en not_active Expired - Fee Related
- 1996-10-15 EP EP96934690A patent/EP0863882B1/en not_active Expired - Lifetime
- 1996-10-16 AR ARP960104776A patent/AR004221A1/es not_active Application Discontinuation
- 1996-10-16 MY MYPI96004287A patent/MY113945A/en unknown
- 1996-10-16 TW TW085112616A patent/TW378206B/zh not_active IP Right Cessation
- 1996-10-16 ZA ZA9608732A patent/ZA968732B/xx unknown
-
1998
- 1998-04-08 NO NO19981623A patent/NO310771B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997014684A1 (en) | 1997-04-24 |
| US6288060B1 (en) | 2001-09-11 |
| PT863882E (pt) | 2002-07-31 |
| EP0863882B1 (en) | 2002-02-06 |
| TW378206B (en) | 2000-01-01 |
| ATE212987T1 (de) | 2002-02-15 |
| AU7292996A (en) | 1997-05-07 |
| DK0863882T3 (da) | 2002-05-06 |
| AR004221A1 (es) | 1998-11-04 |
| AU703096B2 (en) | 1999-03-18 |
| DE69619125D1 (de) | 2002-03-21 |
| EP0863882A1 (en) | 1998-09-16 |
| CA2229710A1 (en) | 1997-04-24 |
| NZ320227A (en) | 1998-11-25 |
| ES2172681T3 (es) | 2002-10-01 |
| JPH11513678A (ja) | 1999-11-24 |
| NO310771B1 (no) | 2001-08-27 |
| NO981623D0 (no) | 1998-04-08 |
| NO981623L (no) | 1998-06-09 |
| MY113945A (en) | 2005-12-14 |
| KR19990045744A (ko) | 1999-06-25 |
| DE69619125T2 (de) | 2002-09-26 |
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