ZA972553B - Aryloxy-and arylthio- substituted pyrimidines and triazines and derivatives thereof - Google Patents

Aryloxy-and arylthio- substituted pyrimidines and triazines and derivatives thereof

Info

Publication number
ZA972553B
ZA972553B ZA972553A ZA972553A ZA972553B ZA 972553 B ZA972553 B ZA 972553B ZA 972553 A ZA972553 A ZA 972553A ZA 972553 A ZA972553 A ZA 972553A ZA 972553 B ZA972553 B ZA 972553B
Authority
ZA
South Africa
Prior art keywords
triazines
arylthio
aryloxy
derivatives
substituted pyrimidines
Prior art date
Application number
ZA972553A
Inventor
Robert J Chorvat
Parthasarathi Rajagopalan
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of ZA972553B publication Critical patent/ZA972553B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/14—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom
    • C07D251/16—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/14—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom
    • C07D251/16—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom
    • C07D251/20—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hydrogen or carbon atoms directly attached to at least one ring carbon atom to only one ring carbon atom with no nitrogen atoms directly attached to a ring carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
ZA972553A 1996-03-27 1997-03-25 Aryloxy-and arylthio- substituted pyrimidines and triazines and derivatives thereof ZA972553B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1421396P 1996-03-27 1996-03-27

Publications (1)

Publication Number Publication Date
ZA972553B true ZA972553B (en) 1998-09-25

Family

ID=21764153

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA972553A ZA972553B (en) 1996-03-27 1997-03-25 Aryloxy-and arylthio- substituted pyrimidines and triazines and derivatives thereof

Country Status (9)

Country Link
US (3) US6326368B1 (en)
EP (1) EP0920318A4 (en)
JP (1) JP2000507550A (en)
AU (1) AU2588697A (en)
CA (1) CA2249580A1 (en)
IL (1) IL120470A0 (en)
NZ (1) NZ331646A (en)
WO (1) WO1997035580A1 (en)
ZA (1) ZA972553B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1178941C (en) 1998-11-12 2004-12-08 纽罗克里恩生物科学有限公司 CRF receptor antagonists and methods relating thereto
PT1129091E (en) 1998-11-12 2003-02-28 Neurocrine Biosciences Inc CRF RECEIVER ANTAGONISTS AND RELATED METHODS
US6432989B1 (en) 1999-08-27 2002-08-13 Pfizer Inc Use of CRF antagonists to treat circadian rhythm disorders
ES2258476T3 (en) * 1999-09-30 2006-09-01 Neurogen Corporation CERTAIN HETEROCICLES REPLACED WITH RENTALS.
US6525067B1 (en) * 1999-11-23 2003-02-25 Pfizer Inc Substituted heterocyclic derivatives
AU2001234180A1 (en) * 2000-02-25 2001-09-03 Japan Tobacco Inc. Benzamide derivative and use thereof
AU2001296255B2 (en) 2000-09-21 2005-07-28 Bristol-Myers Squibb Company Substituted azole derivatives as inhibitors of corticotropin releasing factor
US6825198B2 (en) * 2001-06-21 2004-11-30 Pfizer Inc 5-HT receptor ligands and uses thereof
BR0314196A (en) * 2002-09-10 2005-07-26 Scios Inc Tgf-beta inhibitors
DK1471057T3 (en) * 2003-04-25 2006-05-15 Actimis Pharmaceuticals Inc Pyrimidinylacetic acid derivatives suitable for the treatment of diseases mediated by CRTH2
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
KR101506792B1 (en) * 2013-07-02 2015-03-27 계명대학교 산학협력단 New phenoxytriazine compound or pharmaceutically acceptable salt thereof having inhibitory activity on Hsp90 and medical use thereof
GB201416351D0 (en) * 2014-09-16 2014-10-29 Shire Internat Gmbh Heterocyclic derivatives
WO2016169831A1 (en) * 2015-04-24 2016-10-27 Basf Se Phenoxy- or pyridin-2-yloxy-aminotriazine compounds and their use as herbicides
TWI782504B (en) 2020-05-08 2022-11-01 美商美國禮來大藥廠 (trifluoromethyl)pyrimidine-2-amine compounds
AU2022379985A1 (en) 2021-11-08 2024-04-04 Eli Lilly And Company Deuterated (trifluoromethyl)pyrimidine-2-amine compounds as potentiators of the hmrgx1 receptor

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3843650A (en) * 1972-06-09 1974-10-22 Dow Chemical Co Tris-(polyhalophenoxy)-s-triazine
US3950306A (en) * 1972-06-09 1976-04-13 The Dow Chemical Company Tris-(polyhalophenoxy)-s-triazine flame retardants
JPS5082082A (en) * 1973-11-14 1975-07-03
NZ188244A (en) 1977-09-13 1981-04-24 Ici Australia Ltd 2-substituted pyrimidines compositions growth regulating processes
NZ192708A (en) 1979-02-16 1984-12-14 Ici Australia Ltd Substituted pyrimidines and compositions
IL83488A (en) 1986-08-15 1991-12-15 Ciba Geigy Ag Heterocyclic substituted thioureas,isothioureas and carbodiimides,process for their preparation and insecticidal and acaricidal compositions containing them
DE3725949A1 (en) * 1987-08-05 1989-02-16 Hoechst Ag LIGHT SENSITIVE MIXTURE, LIGHT SENSITIVE COPY MATERIAL MADE THEREOF AND METHOD FOR PRODUCING NEGATIVE RELIEF COPIES
GB8808071D0 (en) 1988-04-07 1988-05-11 Shell Int Research Triazine herbicides
US5185027A (en) 1989-06-14 1993-02-09 Basf Aktiengesellschaft Salicylaldehyde derivatives and salicyclic acid derivatives and their sulfur analogs, and their use as herbicides and bioregulators
EP0466647B1 (en) 1990-07-12 1995-11-29 Ciba-Geigy Ag Process for the photochemical and thermal stabilisation of polyamide fiber materials
US5449777A (en) 1993-07-08 1995-09-12 Ciba-Geigy Corporation Phenolic s-triazines
CN1142817A (en) 1993-10-12 1997-02-12 杜邦麦克制药有限公司 1N-alkyl-N-arylpyrimidinamines and derivatives thereof
TW530047B (en) * 1994-06-08 2003-05-01 Pfizer Corticotropin releasing factor antagonists

Also Published As

Publication number Publication date
EP0920318A1 (en) 1999-06-09
US6326368B1 (en) 2001-12-04
NZ331646A (en) 2000-04-28
JP2000507550A (en) 2000-06-20
EP0920318A4 (en) 2000-03-15
US6818648B2 (en) 2004-11-16
AU2588697A (en) 1997-10-17
WO1997035580A1 (en) 1997-10-02
IL120470A0 (en) 1997-07-13
CA2249580A1 (en) 1997-10-02
US20020040026A1 (en) 2002-04-04
US20030191125A1 (en) 2003-10-09

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