EP0866708A4 - Dihydropyrimidines and uses thereof - Google Patents

Dihydropyrimidines and uses thereof

Info

Publication number
EP0866708A4
EP0866708A4 EP96941406A EP96941406A EP0866708A4 EP 0866708 A4 EP0866708 A4 EP 0866708A4 EP 96941406 A EP96941406 A EP 96941406A EP 96941406 A EP96941406 A EP 96941406A EP 0866708 A4 EP0866708 A4 EP 0866708A4
Authority
EP
European Patent Office
Prior art keywords
dihydropyrimidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96941406A
Other languages
German (de)
French (fr)
Other versions
EP0866708A1 (en
Inventor
Dhanapalan Nagarathnam
Wai C Wong
Shou Wu Miao
Michael A Patane
Charles Gluchowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Synaptic Pharmaceutical Corp
Original Assignee
Merck and Co Inc
Synaptic Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1995/015025 external-priority patent/WO1996014846A1/en
Application filed by Merck and Co Inc, Synaptic Pharmaceutical Corp filed Critical Merck and Co Inc
Priority claimed from PCT/US1996/018573 external-priority patent/WO1997017969A1/en
Publication of EP0866708A1 publication Critical patent/EP0866708A1/en
Publication of EP0866708A4 publication Critical patent/EP0866708A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
EP96941406A 1995-11-16 1996-11-15 Dihydropyrimidines and uses thereof Withdrawn EP0866708A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/US1995/015025 WO1996014846A1 (en) 1994-11-16 1995-11-16 Dihydropyrimidines and uses thereof
WOPCT/US95/15025 1995-11-16
US64877096A 1996-05-16 1996-05-16
US648770 1996-05-16
PCT/US1996/018573 WO1997017969A1 (en) 1995-11-16 1996-11-15 Dihydropyrimidines and uses thereof

Publications (2)

Publication Number Publication Date
EP0866708A1 EP0866708A1 (en) 1998-09-30
EP0866708A4 true EP0866708A4 (en) 1999-05-06

Family

ID=24602162

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96941406A Withdrawn EP0866708A4 (en) 1995-11-16 1996-11-15 Dihydropyrimidines and uses thereof

Country Status (4)

Country Link
EP (1) EP0866708A4 (en)
JP (1) JP2000500470A (en)
AU (1) AU714287B2 (en)
CA (1) CA2237774A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0204317A2 (en) * 1985-06-03 1986-12-10 E.R. Squibb & Sons, Inc. 2-Thio or oxo-4-aryl or heterocyclo-1,5(2H)-pyrimidinedicarboxylic acid diesters and 3-acyl-5-pyrimidinecarboxylic acids and esters
EP0237347A2 (en) * 1986-03-14 1987-09-16 E.R. Squibb & Sons, Inc. 1,2,3,4-Tetrahydro-6-substituted-4-aryl (or heterocyclo)-3-[(substituted amino)carbonyl]-2-thioxo (or oxo)-5-pyrimidinecarboxylic acids and esters

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5659778A (en) * 1979-10-23 1981-05-23 Showa Denko Kk Dimethylthienopyrimidione derivative
US4703120A (en) * 1986-04-28 1987-10-27 Ortho Pharmaceutical Corporation Furo(3,4-d)pyrimidine-2,4-dione derivatives and intermediates thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0204317A2 (en) * 1985-06-03 1986-12-10 E.R. Squibb & Sons, Inc. 2-Thio or oxo-4-aryl or heterocyclo-1,5(2H)-pyrimidinedicarboxylic acid diesters and 3-acyl-5-pyrimidinecarboxylic acids and esters
EP0237347A2 (en) * 1986-03-14 1987-09-16 E.R. Squibb & Sons, Inc. 1,2,3,4-Tetrahydro-6-substituted-4-aryl (or heterocyclo)-3-[(substituted amino)carbonyl]-2-thioxo (or oxo)-5-pyrimidinecarboxylic acids and esters

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9717969A1 *

Also Published As

Publication number Publication date
AU1055897A (en) 1997-06-05
CA2237774A1 (en) 1997-05-22
EP0866708A1 (en) 1998-09-30
JP2000500470A (en) 2000-01-18
AU714287B2 (en) 1999-12-23

Similar Documents

Publication Publication Date Title
EP0790826A4 (en) Dihydropyrimidines and uses thereof
IL122428A0 (en) Minizymes and minribozymes and uses thereof
AU3008297A (en) Dihydropyrimidines and uses thereof
AU7687298A (en) Dihydropyrimidines and uses thereof
HUP9802221A3 (en) Antiparasitic marcfortines and paraherquamides
IL122392A0 (en) Structurally determined metallo-constructs and applications
IL117859A (en) Isothiazolones and their uses
EP0894807A4 (en) GPIb-LIPID COMPLEX AND USES THEREOF
ZA962768B (en) Benzonitriles and benzofluorides
GB2304309B (en) Laminate and use thereof
GB2281830B (en) I/q-modulator and i/q-demodulator
EP0836617A4 (en) Parevins and tachytegrins
ZA964862B (en) Optimized minizymes and miniribozymes and uses thereof
EP0744125A3 (en) Iodo-complex and its use
HUP9801330A3 (en) Novel pka-binding proteins and uses thereof
AU5188296A (en) Carbopeptoids and carbonucleotoids
EP0998578A4 (en) Sel-10 AND USES THEREOF
GB2306981B (en) Roofing component and assembly
PL341293A1 (en) Beta-lypothropin and application thereof
GB9526407D0 (en) Substances and their uses
ZA969612B (en) Dihydropyrimidines and uses thereof
EP0866708A4 (en) Dihydropyrimidines and uses thereof
EP1139972A4 (en) Dihydropyrimidines and uses thereof
GB9501868D0 (en) Assays and uses thereof
GB9515484D0 (en) Substances and their uses

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19980603

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 19990318

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

17Q First examination report despatched

Effective date: 20000620

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20001031