|
US5948768A
(en)
*
|
1995-04-13 |
1999-09-07 |
Milkhaus Laboratory |
Treatment of otitis media by sublingual administration of DNA
|
|
JP2961709B2
(ja)
*
|
1995-04-13 |
1999-10-12 |
ミルカウス ラボラトリー, インコーポレイテッド |
呼吸器系疾患の治療方法および治療用薬剤組成物
|
|
US6096721A
(en)
*
|
1995-04-13 |
2000-08-01 |
Milkhaus Laboratory, Inc. |
Method for treating mucositis by sublingual administration of DNA
|
|
US5635160A
(en)
|
1995-06-07 |
1997-06-03 |
The University Of North Carolina At Chapel Hill |
Dinucleotides useful for the treatment of cystic fibrosis and for hydrating mucus secretions
|
|
US5628984A
(en)
*
|
1995-07-31 |
1997-05-13 |
University Of North Carolina At Chapel Hill |
Method of detecting lung disease
|
|
US5968913A
(en)
*
|
1996-07-03 |
1999-10-19 |
Inspire Pharmaceuticals, Inc. |
Pharmaceutical compositions of uridine triphosphate
|
|
US6319908B1
(en)
|
1996-07-03 |
2001-11-20 |
Inspire Pharmaceuticals, Inc. |
Method for large-scale production of di(uridine 5′-tetraphosphate) and salts thereof
|
|
US5763447C1
(en)
|
1996-07-23 |
2002-05-07 |
Inspire Pharmaceuticals |
Method of preventing or treating pneumonia in immobilized patients with uridine triphosphates and related compounds
|
|
US6159952A
(en)
*
|
1996-11-07 |
2000-12-12 |
Inspire Pharmaceuticals, Inc. |
Method of treating bronchitis with uridine triphosphate and related compounds
|
|
US6998121B2
(en)
|
2003-01-23 |
2006-02-14 |
Milkhaus Laboratory, Inc. |
Method of treatment of connective tissue disorders by administration of streptolysin O
|
|
US6872710B2
(en)
*
|
1997-07-25 |
2005-03-29 |
Inspire Pharmaceuticals, Inc. |
Di(uridine 5′)-tetraphosphate and salts thereof
|
|
TW593331B
(en)
*
|
1997-07-25 |
2004-06-21 |
Inspire Pharmaceuticals Inc |
Method for large-scale production of di(uridine 5')-tetraphosphate and salts thereof
|
|
PT1012154E
(pt)
|
1997-07-25 |
2004-08-31 |
Inspire Pharmaceuticals Inc |
Sais de di(5'-tetrafosfato de uridina), metodo para a sua preparacao, e suas utilizacoes
|
|
ID29198A
(id)
*
|
1997-08-29 |
2001-08-09 |
Univ North Carolina |
Pemakaian uridin 5'-difosfat dan persamaannya untuk mengobati penyakit paru-paru
|
|
US6926911B1
(en)
*
|
1998-12-22 |
2005-08-09 |
The University Of North Carolina At Chapel Hill |
Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs
|
|
EP1139746A4
(en)
*
|
1998-12-22 |
2003-09-17 |
Univ North Carolina |
CONNECTIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY DISEASES AND THE ADMINISTRATION OF MEDICINAL SUBSTANCES
|
|
WO2000050024A2
(en)
|
1999-02-26 |
2000-08-31 |
Inspire Pharmaceuticals, Inc. |
Method of promoting mucosal hydration with certain uridine, adenine and cytidine diphosphates and analogs thereof
|
|
AU782966B2
(en)
*
|
1999-06-08 |
2005-09-15 |
University Of Iowa Research Foundation, The |
Compounds and methods to enhance RAAV transduction
|
|
US7241447B1
(en)
*
|
1999-10-07 |
2007-07-10 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors and uses thereof
|
|
US7115585B2
(en)
*
|
2000-08-21 |
2006-10-03 |
Inspire Pharmaceuticals, Inc. |
Compositions for treating epithelial and retinal tissue diseases
|
|
US7452870B2
(en)
*
|
2000-08-21 |
2008-11-18 |
Inspire Pharmaceuticals, Inc. |
Drug-eluting stents coated with P2Y12 receptor antagonist compound
|
|
US7018985B1
(en)
|
2000-08-21 |
2006-03-28 |
Inspire Pharmaceuticals, Inc. |
Composition and method for inhibiting platelet aggregation
|
|
WO2003000056A1
(en)
|
2001-06-25 |
2003-01-03 |
Inspire Pharmaceuticals, Inc. |
Joint lubrication with p2y purinergic receptor agonists
|
|
JP3823162B2
(ja)
*
|
2001-07-31 |
2006-09-20 |
株式会社エイアンドティー |
臨床検査分析装置、臨床検査分析方法および臨床検査分析プログラム
|
|
MXPA04004215A
(es)
*
|
2001-11-06 |
2004-07-08 |
Inspire Pharmaceuticals Inc |
Metodo para el tratamiento o la prevencion de enfermedades inflamatorias.
|
|
US20060196365A1
(en)
*
|
2001-12-11 |
2006-09-07 |
Garman Michael H |
Combined water cooler and hot beverage maker
|
|
US6858615B2
(en)
|
2002-02-19 |
2005-02-22 |
Parion Sciences, Inc. |
Phenyl guanidine sodium channel blockers
|
|
US7435724B2
(en)
|
2002-02-27 |
2008-10-14 |
Inspire Pharmaceutical, Inc. |
Degradation-resistant mononucleoside phosphate compounds
|
|
US20050220720A1
(en)
*
|
2002-05-02 |
2005-10-06 |
David Edwards |
Formulations limiting spread of pulmonary infections
|
|
EP1531795A4
(en)
|
2002-05-02 |
2011-02-23 |
Harvard College |
FORMULATIONS FOR LIMITING THE RETENTION OF LUNG INFECTIONS
|
|
US7629312B2
(en)
|
2003-01-23 |
2009-12-08 |
Milkhaus Laboratory, Inc. |
Method of treatment of tendonitis by administration of streptolysin O
|
|
WO2004090145A2
(en)
*
|
2003-03-31 |
2004-10-21 |
University Of Iowa Research Foundation |
Compounds and methods to enhance raav transduction
|
|
BRPI0411900B8
(pt)
|
2003-06-26 |
2021-05-25 |
Biotron Ltd |
compostos e composições farmacêuticas compreendendo os mesmos
|
|
US20090253714A1
(en)
*
|
2003-08-20 |
2009-10-08 |
Johnson Michael R |
Methods of reducing risk of infection from pathogens
|
|
US7745442B2
(en)
|
2003-08-20 |
2010-06-29 |
Parion Sciences, Inc. |
Methods of reducing risk of infection from pathogens
|
|
CA2547972A1
(en)
*
|
2003-11-24 |
2005-06-09 |
Georgia State University Research Foundation, Inc. |
Fused ring dicationic anti-protozoan agents and their prodrugs
|
|
US20050207983A1
(en)
*
|
2004-03-05 |
2005-09-22 |
Pulmatrix, Inc. |
Formulations decreasing particle exhalation
|
|
US20070276020A1
(en)
*
|
2004-03-08 |
2007-11-29 |
Boykin David W |
Dicationic Compounds For Activity Against Trichomonas Vaginalis
|
|
US20070099968A1
(en)
*
|
2004-06-26 |
2007-05-03 |
Biotron Limited |
Antiviral compounds and methods
|
|
GB0417886D0
(en)
*
|
2004-08-11 |
2004-09-15 |
Univ Cardiff |
Method and means for enhanced pulmonary delivery
|
|
EP1874801A4
(en)
|
2005-03-07 |
2009-03-25 |
Univ North Carolina |
MEANS OF INHIBITING RECA ACTIVITIES FOR THE CONTROL OF ANTIBIOTIC-SITES BACTERIAL PATHOGENESE
|
|
AU2006201739A1
(en)
*
|
2005-05-05 |
2006-11-23 |
The University Of North Carolina At Chapel Hill |
Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles
|
|
EP1906922A2
(en)
*
|
2005-05-18 |
2008-04-09 |
Pulmatrix, Inc. |
Formulations for alteration of biophysical properties of mucosal lining
|
|
US7964619B2
(en)
|
2005-06-03 |
2011-06-21 |
The University Of North Carolina At Chapel Hill |
Teraryl components as antiparasitic agents
|
|
AU2006202083A1
(en)
*
|
2005-06-03 |
2006-12-21 |
Reto Brun |
Linear dicationic terphenyls and their aza analogues as antiparasitic agents
|
|
US20100249175A1
(en)
*
|
2005-12-02 |
2010-09-30 |
Wilson W David |
Dicationic compounds which selectively recognize G-quadruplex DNA
|
|
EP2019964A2
(en)
*
|
2006-04-28 |
2009-02-04 |
University of Iowa Research Foundation |
Methods and compounds to modulate parvovirus transduction of mammalian cells or to alter virus infection. method to identify a viral receptor or co-receptor
|
|
US20080260863A1
(en)
*
|
2007-04-20 |
2008-10-23 |
Pre Holding, Inc. |
Compositions for mucociliary clearance and methods for administering same
|
|
AU2008266856A1
(en)
|
2007-06-18 |
2008-12-24 |
University Of Louisville Research Foundation, Inc. |
Family of PFKFB3 inhibitors with anti-neoplastic activities
|
|
US20100280098A1
(en)
*
|
2007-10-05 |
2010-11-04 |
Juliano Rudolph L |
Receptor targeted oligonucleotides
|
|
WO2009049159A1
(en)
|
2007-10-10 |
2009-04-16 |
Parion Sciences, Inc. |
Delivering osmolytes by nasal cannula
|
|
US20100331368A1
(en)
*
|
2007-10-17 |
2010-12-30 |
Tidwell Richard R |
2,5-diaryl selenophene compounds, aza 2,5-diaryl thiophene compounds, and their prodrugs as antiprotozoal agents
|
|
MX2010011050A
(es)
|
2008-04-09 |
2010-11-01 |
Univ North Carolina |
Metodos para regular el reodernamiento citoesqueletico de actina y la formacion de aberturas intercelulares.
|
|
AU2009298367A1
(en)
*
|
2008-10-01 |
2010-04-08 |
The University Of North Carolina At Chapel Hill |
Hematopoietic protection against chemotherapeutic compounds using selective cyclin-dependent kinase 4/6 inhibitors
|
|
EP2341906A4
(en)
*
|
2008-10-01 |
2012-06-13 |
Univ North Carolina |
HEMATOPOIETIC PROTECTION AGAINST IONIZATION RADIATION USING SELF-ACTIVE CYCLINE-DEPENDENT KINASE-4/6-HEMMER
|
|
RU2577698C2
(ru)
|
2009-03-26 |
2016-03-20 |
Пулмэтрикс, Инк. |
Сухие порошкообразные составы и способы лечения легочных заболеваний
|
|
EP3718560A3
(en)
|
2009-05-13 |
2020-12-09 |
The University of North Carolina at Chapel Hill |
Cyclin dependent kinase inhibitors and methods of use
|
|
WO2011008756A1
(en)
|
2009-07-13 |
2011-01-20 |
Irix Pharmaceuticals |
Synthesis of prostanoids
|
|
CA2768582C
(en)
|
2009-07-24 |
2017-02-14 |
University Of Tennessee Research Foundation |
Spectinamides as anti-tuberculosis agents
|
|
WO2011018468A1
(en)
*
|
2009-08-10 |
2011-02-17 |
P2-Science Aps |
Utp for the diagnosis of stenoses and other conditions of restricted blood flow
|
|
JP5922111B2
(ja)
*
|
2010-06-23 |
2016-05-24 |
ピーツー−サイエンス・エペイエス |
充血剤注入と同時に血圧測定を行う診断目的の動脈用複合カテーテル
|
|
WO2012030645A1
(en)
|
2010-08-30 |
2012-03-08 |
Pulmatrix, Inc. |
Respirably dry powder comprising calcium lactate, sodium chloride and leucine
|
|
US9061352B2
(en)
|
2010-08-30 |
2015-06-23 |
Pulmatrix, Inc. |
Dry powder formulations and methods for treating pulmonary diseases
|
|
CA2812414C
(en)
|
2010-09-29 |
2020-09-22 |
Pulmatrix, Inc. |
Monovalent metal cation dry powders for inhalation
|
|
US9433576B2
(en)
|
2010-09-29 |
2016-09-06 |
Pulmatrix, Inc. |
Cationic dry powders
|
|
AU2011329763A1
(en)
|
2010-11-17 |
2013-05-09 |
Brigham And Women's Hospital |
Protection of renal tissues from ischemia through inhibition of the proliferative kinases CDK4 and CDK6
|
|
EP2717855A4
(en)
*
|
2011-06-07 |
2014-11-12 |
Parion Sciences Inc |
PROCESSING METHODS
|
|
US8945605B2
(en)
|
2011-06-07 |
2015-02-03 |
Parion Sciences, Inc. |
Aerosol delivery systems, compositions and methods
|
|
AR086745A1
(es)
|
2011-06-27 |
2014-01-22 |
Parion Sciences Inc |
3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
|
|
JP2015509788A
(ja)
|
2012-02-29 |
2015-04-02 |
パルマトリックス,インコーポレイテッド |
吸入に適した乾燥粉末
|
|
US9833207B2
(en)
|
2012-08-08 |
2017-12-05 |
William Harrison Zurn |
Analysis and clearing module, system and method
|
|
CN108658876A
(zh)
|
2012-12-17 |
2018-10-16 |
帕里昂科学公司 |
3,5-二氨基-6-氯-n-(n-(4-苯基丁基)甲脒基)吡嗪-2-甲酰胺化合物
|
|
UA120343C2
(uk)
|
2012-12-17 |
2019-11-25 |
Періон Сайєнсіз, Інк. |
Похідні хлорпіразинкарбоксаміду, які мають активність блокування епітеліальних натрієвих каналів
|
|
US9962533B2
(en)
|
2013-02-14 |
2018-05-08 |
William Harrison Zurn |
Module for treatment of medical conditions; system for making module and methods of making module
|
|
CN105407723A
(zh)
|
2013-03-15 |
2016-03-16 |
G1治疗公司 |
高效的抗赘生剂和抗增生剂
|
|
WO2014144847A2
(en)
|
2013-03-15 |
2014-09-18 |
G1 Therapeutics, Inc. |
Hspc-sparing treatments for rb-positive abnormal cellular proliferation
|
|
EP2981247B1
(en)
|
2013-04-01 |
2023-06-07 |
Pulmatrix Operating Company, Inc. |
Tiotropium dry powders
|
|
CA2925927C
(en)
|
2013-09-30 |
2022-09-06 |
George Petros Yiannikouros |
Novel synthesis routes for prostaglandins and prostaglandin intermediates using metathesis
|
|
US9102633B2
(en)
|
2013-12-13 |
2015-08-11 |
Parion Sciences, Inc. |
Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
|
|
US20150297607A1
(en)
|
2014-04-17 |
2015-10-22 |
G1 Therapeutics, Inc. |
Tricyclic Lactams for Use in the Protection of Normal Cells During Chemotherapy
|
|
WO2016040848A1
(en)
|
2014-09-12 |
2016-03-17 |
G1 Therapeutics, Inc. |
Treatment of rb-negative tumors using topoisomerase inhibitors in combination with cyclin dependent kinase 4/6 inhibitors
|
|
WO2016040858A1
(en)
|
2014-09-12 |
2016-03-17 |
G1 Therapeutics, Inc. |
Combinations and dosing regimes to treat rb-positive tumors
|
|
CN104306028B
(zh)
*
|
2014-09-26 |
2016-08-17 |
张清玲 |
一种用于呼吸道细菌16S rRNA基因序列检测的痰液收集方法
|
|
WO2017035401A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Amide compounds for treatment of immune and inflammatory disorders
|
|
AR106018A1
(es)
|
2015-08-26 |
2017-12-06 |
Achillion Pharmaceuticals Inc |
Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
|
|
EP3340983B1
(en)
|
2015-08-26 |
2023-10-04 |
Achillion Pharmaceuticals, Inc. |
Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders
|
|
WO2017035405A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Amino compounds for treatment of immune and inflammatory disorders
|
|
US11702672B2
(en)
|
2016-02-08 |
2023-07-18 |
University Of Iowa Research Foundation |
Methods to produce chimeric adeno-associated virus/bocavirus parvovirus
|
|
EP3426787A1
(en)
|
2016-03-07 |
2019-01-16 |
University of Iowa Research Foundation |
Aav-mediated expression using a synthetic promoter and enhancer
|
|
US12173305B2
(en)
|
2016-05-26 |
2024-12-24 |
University Of Iowa Research Foundation |
cis and trans requirements for terminal resolution of human bocavirus 1
|
|
RU2019102647A
(ru)
|
2016-07-01 |
2020-08-03 |
Г1 Терапьютикс, Инк. |
Антипролиферационные средства на основе пиримидина
|
|
US10413583B2
(en)
|
2016-11-30 |
2019-09-17 |
The University Of Chicago |
Synthetic substrates for enzymes that catalyze reactions of modified cysteines and related methods
|
|
US11142775B2
(en)
|
2017-01-13 |
2021-10-12 |
University Of Iowa Research Foundation |
Bocaparvovirus small noncoding RNA and uses thereof
|
|
WO2018160891A1
(en)
|
2017-03-01 |
2018-09-07 |
Achillion Pharmaceutical, Inc. |
Pharmaceutical compounds for treatment of medical disorders
|
|
MX2019010381A
(es)
|
2017-03-01 |
2020-01-21 |
Achillion Pharmaceuticals Inc |
Compuestos farmaceuticos de arilo, heteroarilo y heterociclicos para el tratamiento de trastornos medicos.
|
|
WO2019028284A1
(en)
|
2017-08-02 |
2019-02-07 |
Achillion Pharmaceuticals, Inc. |
THERAPEUTIC REGIMES FOR THE TREATMENT OF NOCTURNAL PAROXYSTIC HEMOGLOBINURIA
|
|
GB2604314A
(en)
|
2017-09-22 |
2022-09-07 |
Nerudia Ltd |
Device, system and method
|
|
US11439608B2
(en)
|
2017-09-25 |
2022-09-13 |
Qun Lu |
Roles of modulators of intersectin-CDC42 signaling in Alzheimer's disease
|
|
US11541120B2
(en)
|
2017-12-05 |
2023-01-03 |
Anthos Partners, Lp |
Phosphonium-based ionic drug conjugates
|
|
MX2021002640A
(es)
|
2018-09-06 |
2021-07-16 |
Achillion Pharmaceuticals Inc |
Formas morficas de los inhibidores del factor d del complemento.
|
|
US11814391B2
(en)
|
2018-09-06 |
2023-11-14 |
Achillion Pharmaceuticals, Inc. |
Macrocyclic compounds for the treatment of medical disorders
|
|
MX2021003425A
(es)
|
2018-09-25 |
2021-07-16 |
Achillion Pharmaceuticals Inc |
Formas morficas de los inhibidores del factor d del complemento.
|
|
AU2019406830A1
(en)
|
2018-12-17 |
2021-07-08 |
Achillion Pharmaceuticals, Inc. |
Targeted dosing for the treatment of complement mediated disorders
|
|
WO2020198062A1
(en)
|
2019-03-22 |
2020-10-01 |
Achillion Pharmaceuticals, Inc. |
Pharmaceutical compounds for the treatment of complement mediated disorders
|
|
KR20230012547A
(ko)
|
2020-05-19 |
2023-01-26 |
쥐원 쎄라퓨틱스, 인크. |
의학적 장애의 치료를 위한 시클린-의존성 키나제 억제 화합물
|
|
US10988479B1
(en)
|
2020-06-15 |
2021-04-27 |
G1 Therapeutics, Inc. |
Morphic forms of trilaciclib and methods of manufacture thereof
|