ZA966163B - Novel galanthamine derivatives, process for the preparation thereof, their application as medical drugs, and pharmaceutical compositions containing said derivatives. - Google Patents

Novel galanthamine derivatives, process for the preparation thereof, their application as medical drugs, and pharmaceutical compositions containing said derivatives.

Info

Publication number
ZA966163B
ZA966163B ZA9606163A ZA966163A ZA966163B ZA 966163 B ZA966163 B ZA 966163B ZA 9606163 A ZA9606163 A ZA 9606163A ZA 966163 A ZA966163 A ZA 966163A ZA 966163 B ZA966163 B ZA 966163B
Authority
ZA
South Africa
Prior art keywords
derivatives
pharmaceutical compositions
compositions containing
preparation
application
Prior art date
Application number
ZA9606163A
Other languages
English (en)
Inventor
Claude Thal
Aude Mary
Pierre Potier
Dolor Renko
Yves Christen
Catherine Guillou
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of ZA966163B publication Critical patent/ZA966163B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA9606163A 1995-07-19 1996-07-19 Novel galanthamine derivatives, process for the preparation thereof, their application as medical drugs, and pharmaceutical compositions containing said derivatives. ZA966163B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9514821.9A GB9514821D0 (en) 1995-07-19 1995-07-19 Galanthamine derivatives

Publications (1)

Publication Number Publication Date
ZA966163B true ZA966163B (en) 1997-02-10

Family

ID=10777948

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9606163A ZA966163B (en) 1995-07-19 1996-07-19 Novel galanthamine derivatives, process for the preparation thereof, their application as medical drugs, and pharmaceutical compositions containing said derivatives.

Country Status (16)

Country Link
US (1) US5958903A (no)
EP (1) EP0839149B9 (no)
JP (1) JP4177894B2 (no)
AT (1) ATE264332T1 (no)
AU (1) AU6662396A (no)
CA (1) CA2227235C (no)
DE (1) DE69632194T2 (no)
DK (1) DK0839149T3 (no)
ES (1) ES2218596T3 (no)
GB (1) GB9514821D0 (no)
IL (1) IL122739A0 (no)
MX (1) MX9800407A (no)
NO (1) NO980215L (no)
PT (1) PT839149E (no)
WO (1) WO1997003987A1 (no)
ZA (1) ZA966163B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1163224C (zh) * 1998-09-30 2004-08-25 武田药品工业株式会社 改善膀胱排泄能力的药物
EP1133230A4 (en) * 1998-11-23 2004-05-26 Bonnie M Davis DOSAGE FORMULAS FOR ACETYLCHOLINESTERASE INHIBITORS
SK287676B6 (sk) 1998-12-24 2011-05-06 Janssen Pharmaceutica N. V. Prostriedok s riadeným uvoľňovaním obsahujúci galantamín, spôsob jeho prípravy, dávková forma a farmaceutické balenie s jeho obsahom a použitie galantamínu na výrobu tohto prostriedku
US8603546B2 (en) * 1999-01-11 2013-12-10 Herbaceuticals Inc. Herbal supplement for increased muscle strength and endurance for athletes
EP1150695B1 (en) * 1999-01-11 2007-02-28 Atanas Russinov Djananov Herbal supplement for increased muscle strength and endurance for athletes
ES2211056T3 (es) * 1999-03-31 2004-07-01 Eisai Co., Ltd. Composiciones estabilizadas que contienen farmacos nootropicos.
DE50101827D1 (de) * 2000-03-31 2004-05-06 Sanochemia Pharmazeutika Ag Wi Neue derivate und analoga von galanthamin
DE10129265A1 (de) * 2001-06-18 2003-01-02 Hf Arzneimittelforsch Gmbh Wirkstoff-Kombination zur medikamentösen Sucht- oder Rauschmitteltherapie
JP4721386B2 (ja) * 2001-07-10 2011-07-13 第一三共株式会社 新規ガランタミン類縁体
DE10134038A1 (de) * 2001-07-12 2003-02-06 Hf Arzneimittelforsch Gmbh Wirkstoff-Kombination zur medikamentösen Therapie der Nikotinabhängigkeit
US20060069251A1 (en) * 2002-03-25 2006-03-30 Ulrich Jordis Methods for producing norgalanthamine, as well as isomers, salts and hydrates thereof
US20060111341A1 (en) * 2003-09-29 2006-05-25 Angelika Bodenteich Use of galanthamine and the derivatives thereof in the production of medicaments
AT414125B (de) * 2003-09-29 2006-09-15 Sanochemia Pharmazeutika Ag Neue derivate des 4a,5,9,10,11,12-hexahydro- benzofuro(3a,3,2)(2) benzazepin, verfahren zu deren herstellung sowie deren verwendung zur herstellung von arzneimitteln
WO2005065661A2 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Immediate, controlled and sustained release formulations of galanthamine
CA2552114A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Solid dosage formulations of galantamine
PL1895994T3 (pl) * 2005-05-13 2011-02-28 Alza Corp Wielowarstwowy system podawania leków z barierą zabezpieczającą przed wypływaniem materiału ze zbiornika
US20070104771A1 (en) * 2005-09-23 2007-05-10 Jay Audett Transdermal galantamine delivery system
CA2736982C (en) * 2008-09-11 2019-01-15 I.B.R. Israeli Biotechnology Research Ltd. Leucojum bulb extracts and use thereof
WO2010123184A1 (ko) * 2009-04-24 2010-10-28 제주대학교 산학협력단 노르갈란타민 화합물을 유효성분으로 함유하는 탈모 질환의 예방 및 치료용 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663318A (en) * 1986-01-15 1987-05-05 Bonnie Davis Method of treating Alzheimer's disease
US4735169A (en) * 1986-09-03 1988-04-05 Nordson Corporation Adhesive applicator assembly
EP0363415B1 (en) * 1987-05-04 2008-10-15 Davis, Bonnie Compounds for the treatment of alzheimer's disease
US5336675A (en) * 1991-05-14 1994-08-09 Ernir Snorrason Method of treating mania in humans
US6323195B1 (en) * 1993-10-15 2001-11-27 Aventis Pharmaceuticals Inc. Galanthamine derivatives as acetylcholinesterase inhibitors
US5428159A (en) * 1994-04-08 1995-06-27 Ciba-Geigy Corporation Method of manufacture of (-)-galanthamine in high yield and purity substantially free of epigalanthamine

Also Published As

Publication number Publication date
NO980215D0 (no) 1998-01-16
EP0839149A1 (fr) 1998-05-06
IL122739A0 (en) 1998-08-16
ES2218596T3 (es) 2004-11-16
CA2227235C (fr) 2010-08-31
DE69632194T2 (de) 2005-03-17
JPH11509541A (ja) 1999-08-24
CA2227235A1 (fr) 1997-02-06
PT839149E (pt) 2004-08-31
EP0839149B1 (fr) 2004-04-14
AU6662396A (en) 1997-02-18
GB9514821D0 (en) 1995-09-20
MX9800407A (es) 1998-04-30
DE69632194D1 (de) 2004-05-19
NO980215L (no) 1998-01-16
WO1997003987A1 (fr) 1997-02-06
ATE264332T1 (de) 2004-04-15
EP0839149B9 (fr) 2005-03-09
JP4177894B2 (ja) 2008-11-05
US5958903A (en) 1999-09-28
DK0839149T3 (da) 2004-08-09

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