ZA964653B - Non-irritation non-sensitizing non-ototoxic otic anti-bacterial compositions - Google Patents

Non-irritation non-sensitizing non-ototoxic otic anti-bacterial compositions

Info

Publication number
ZA964653B
ZA964653B ZA964653A ZA964653A ZA964653B ZA 964653 B ZA964653 B ZA 964653B ZA 964653 A ZA964653 A ZA 964653A ZA 964653 A ZA964653 A ZA 964653A ZA 964653 B ZA964653 B ZA 964653B
Authority
ZA
South Africa
Prior art keywords
amount effective
ototoxic
sensitizing
irritation
composition
Prior art date
Application number
ZA964653A
Other languages
English (en)
Inventor
Shivaji Purwar
David Goldman
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA964653B publication Critical patent/ZA964653B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Endoscopes (AREA)
ZA964653A 1995-06-06 1996-06-05 Non-irritation non-sensitizing non-ototoxic otic anti-bacterial compositions ZA964653B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46504895A 1995-06-06 1995-06-06

Publications (1)

Publication Number Publication Date
ZA964653B true ZA964653B (en) 1996-12-12

Family

ID=23846298

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA964653A ZA964653B (en) 1995-06-06 1996-06-05 Non-irritation non-sensitizing non-ototoxic otic anti-bacterial compositions

Country Status (17)

Country Link
US (1) US5965549A (fr)
EP (1) EP0782448B1 (fr)
CN (1) CN1137685C (fr)
AT (1) ATE214931T1 (fr)
AU (1) AU708540B2 (fr)
CA (1) CA2199294C (fr)
DE (1) DE69620136T2 (fr)
DK (1) DK0782448T3 (fr)
ES (1) ES2173287T3 (fr)
HK (1) HK1002552A1 (fr)
IL (1) IL120317A (fr)
MX (1) MX9701731A (fr)
NZ (1) NZ309624A (fr)
PT (1) PT782448E (fr)
TW (1) TW464499B (fr)
WO (1) WO1996039146A1 (fr)
ZA (1) ZA964653B (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
AR020661A1 (es) * 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
WO2000018404A1 (fr) * 1998-09-30 2000-04-06 Alcon Laboratories, Inc. Compositions antibiotiques pour le traitement des yeux, des oreilles et du nez
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6500360B2 (en) * 1999-06-18 2002-12-31 Bernard Bendiner Sorbic acid and/or its derivatives, such as potassium sorbate, as a preventative for rust, corrosion and scale on metal surfaces
US6156294A (en) 1999-11-28 2000-12-05 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
US7064132B2 (en) * 1999-11-28 2006-06-20 Scientific Development And Research, Inc. Composition and method for treatment of otitis external
ES2160090B1 (es) * 2000-03-16 2002-07-01 Vita Invest Sa Composiciones acuosas de ciprofloxacino, contenidas en envases monodosis y su utilizacion.
WO2002007704A2 (fr) * 2000-07-26 2002-01-31 Alcon Universal Ltd. Procede ameliore de fabrication de compositions contenant de la ciprofloxacine et de l'hydrocortisone
MXPA03002342A (es) 2000-09-25 2004-10-15 Bayer Healthcare Llc Combinaciones microbianas opticas para el tratamiento de animales con la membrana timpanica rota.
MXPA04002576A (es) 2001-09-21 2004-06-18 Alcon Inc Metodo para tratar infecciones del oido medio.
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
US20040101506A1 (en) * 2002-11-25 2004-05-27 Fust Charles A. Composition for the prevention and treatment of inflammation of the ear
US7842791B2 (en) 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
US20050009931A1 (en) * 2003-03-20 2005-01-13 Britten Nancy Jean Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
US20050004098A1 (en) * 2003-03-20 2005-01-06 Britten Nancy Jean Dispersible formulation of an anti-inflammatory agent
US20040214753A1 (en) * 2003-03-20 2004-10-28 Britten Nancy Jean Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
DK1608407T3 (da) * 2003-03-20 2006-12-04 Pharmacia Corp Dispergébar formulering af et antiinflammatorisk middel
AU2004258746A1 (en) * 2003-07-31 2005-02-03 Pharmacia & Upjohn Company Llc Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
CN1829510A (zh) * 2003-07-31 2006-09-06 法马西亚和厄普乔恩公司 抗炎剂的可分散性制剂
US8940321B2 (en) 2003-12-12 2015-01-27 Otic Pharma Ltd. Compositions for treatment of ear disorders and methods of use thereof
CA2548892C (fr) * 2003-12-12 2015-10-27 Eran Eilat Compositions pour le traitement de troubles auriculaires et procedes d'utilisation de ces compositions
US20060019987A1 (en) * 2004-07-23 2006-01-26 Fust Charles A Methods and compositions for inhibiting, destroying, and/or inactivating viruses
PL1962805T3 (pl) 2005-12-08 2017-01-31 Insmed Incorporated Kompozycje środków przeciwzapalnych oparte na lipidach do leczenia infekcji płucnych
WO2008137717A1 (fr) 2007-05-04 2008-11-13 Transave, Inc. Compositions de médicaments multicationiques pour réduire des interactions avec des biomolécules polyanioniques et leurs procédés et utilisations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
UA111147C2 (uk) * 2009-11-11 2016-04-11 Байєр Б.В. Способи та композиції для лікування або профілактики зовнішнього отиту
DK2366408T3 (da) 2010-03-01 2012-10-22 Salvat Lab Sa Vandige, klare opløsninger af fluocinolonacetonid til behandling af inflammation i øret
HU227743B1 (en) * 2011-07-22 2012-02-28 Debreceni Egyetem Eardrop composition and process for producing this
BR112014013564A2 (pt) * 2011-12-09 2017-06-13 Lupin Ltd composição farmacêutica tópica destinada à aplicação ao olho, ouvido ou nariz
RU2018135921A (ru) 2012-11-29 2019-02-05 Инсмед Инкорпорейтед Стабилизированные составы ванкомицина
ES2755941T3 (es) 2014-05-15 2020-04-24 Insmed Inc Métodos para tratar infecciones pulmonares micobacterianas no tuberculosas
US9393243B1 (en) 2015-07-14 2016-07-19 Nilesh Parikh Topical Ciprofloxacin compositions
WO2019191627A1 (fr) 2018-03-30 2019-10-03 Insmed Incorporated Procédés pour la fabrication continue de produits médicamenteux liposomaux

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4025620A (en) * 1975-10-22 1977-05-24 Leo Pharmaceutical Products Ltd., A/S Treatment of canine otitis and composition therefor
US4670444B1 (en) * 1980-09-03 1999-02-09 Bayer Ag and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds
DE3471639D1 (en) * 1983-03-31 1988-07-07 Payne Packaging Ltd Improvements in or relating to tapes
DE3537761A1 (de) * 1985-10-24 1987-04-30 Bayer Ag Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure
DE3704907A1 (de) * 1987-02-17 1988-08-25 Bayer Ag Topisch anwendbare zubereitungen von gyrase-inhibitoren in kombination mit kortikosteroiden
DE3902079A1 (de) * 1988-04-15 1989-10-26 Bayer Ag I.m. injektionsformen von gyrase-inhibitoren
US5061729A (en) * 1988-06-08 1991-10-29 Biogal Gyogyszergyar Pharmaceutical composition and process for preparing the same
US5271939A (en) * 1988-10-03 1993-12-21 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation
US5260073A (en) * 1990-05-21 1993-11-09 Norwich Eaton Pharmaceuticals, Inc. Use of phenylpropanolamine as a mucus secretogogue in the upper airways
WO1994010976A1 (fr) * 1992-11-16 1994-05-26 Ciba Vision Ag, Hettlingen Systeme d'administration de medicaments ophtalmiques a base de borate/alcool polyvinylique
US5422116A (en) * 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system
ES2088742B1 (es) * 1994-06-29 1997-03-16 Salvat Lab Sa Composicion antibiotica de aplicacion otica.

Also Published As

Publication number Publication date
IL120317A (en) 2000-08-13
DK0782448T3 (da) 2002-07-08
IL120317A0 (en) 1998-06-15
DE69620136D1 (de) 2002-05-02
AU5984096A (en) 1996-12-24
TW464499B (en) 2001-11-21
US5965549A (en) 1999-10-12
EP0782448B1 (fr) 2002-03-27
EP0782448A1 (fr) 1997-07-09
MX9701731A (es) 1997-10-31
ES2173287T3 (es) 2002-10-16
WO1996039146A1 (fr) 1996-12-12
DE69620136T2 (de) 2002-08-01
CN1160999A (zh) 1997-10-01
CA2199294A1 (fr) 1996-12-12
AU708540B2 (en) 1999-08-05
EP0782448A4 (fr) 1998-05-20
PT782448E (pt) 2002-07-31
NZ309624A (en) 1999-04-29
CA2199294C (fr) 2000-09-19
CN1137685C (zh) 2004-02-11
HK1002552A1 (en) 1998-09-04
ATE214931T1 (de) 2002-04-15

Similar Documents

Publication Publication Date Title
ZA964653B (en) Non-irritation non-sensitizing non-ototoxic otic anti-bacterial compositions
CA2289717A1 (fr) Nouveau traitement de la constipation
ID26221A (id) Komposisi-komposisi farmasi yang dapat dijadikan gel
IE831611L (en) Topical anti-inflammatory compositions
WO2001030802A3 (fr) Traitements therapeutiques pour des deficiences en cellules sanguines
AU2002231889A1 (en) Halogenated composition, method for preparing same and uses thereof
US5747070A (en) Methods for the treatment of herpes virus infections
MXPA02012075A (es) Composicion para mediar el dolor y aparato y metodo para utilizarla.
MX9603596A (es) Perfluoropolieteres o composiciones de los mismos para prevencion y tratamiento de infecciones virales topicas.
KR950016760A (ko) 치질 치료제
MXPA01013460A (es) Formulaciones topicas que comprenden agentes de penetracion de la piel y uso de las mismas.
JPH07277988A (ja) 局所用掻痒除去、治療剤
FR2754824B1 (fr) Nouvelle composition contenant du chitosan
WO1998014193A1 (fr) Utilisation d'un antagoniste de la substance p dans la fabrication d'un medicament pour traiter les douleurs oculaires
PT1140001E (pt) Composicao para tratamento de queimaduras
ES2145740T3 (es) Composiciones de factor de crecimiento, preparacion y uso.
EP0985414A3 (fr) Méthode de traitement du glaucôme et de la rétinopathie ischémique
WO2000078772A3 (fr) Agents antibiotiques
Braun-Falco et al. Topical Treatment of Dermatoses
MX9801538A (es) Metodos y composiciones para el tratamiento de infecciones fungales en mamiferos.
MX9500324A (es) Compuestos farmaceuticos y el uso de los mismos en el tratamiento de enfermedades neurologicas y sus etiologias sintomaticas relacionadas.
MY100229A (en) Topical anti-inflammatory compositions.
UA30359A (uk) Спосіб лікування гнійних ран
MX9605153A (es) Agentes farmaceuticos para el tratamiento de enfermedades inflamatorias cronicas y agudas.
CA2255521A1 (fr) Compositions pour le traitement des brulures