DK0782448T3 - Ikke-irriterende, ikke-sensibiliserende, ikke-ototoksiske antibakterielle ørepræparater - Google Patents

Ikke-irriterende, ikke-sensibiliserende, ikke-ototoksiske antibakterielle ørepræparater

Info

Publication number
DK0782448T3
DK0782448T3 DK96917172T DK96917172T DK0782448T3 DK 0782448 T3 DK0782448 T3 DK 0782448T3 DK 96917172 T DK96917172 T DK 96917172T DK 96917172 T DK96917172 T DK 96917172T DK 0782448 T3 DK0782448 T3 DK 0782448T3
Authority
DK
Denmark
Prior art keywords
amount effective
ototoxic
sensitizing
irritating
composition
Prior art date
Application number
DK96917172T
Other languages
English (en)
Inventor
Shivaji Purwar
David Goldman
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0782448T3 publication Critical patent/DK0782448T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Endoscopes (AREA)
DK96917172T 1995-06-06 1996-06-05 Ikke-irriterende, ikke-sensibiliserende, ikke-ototoksiske antibakterielle ørepræparater DK0782448T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46504895A 1995-06-06 1995-06-06
PCT/US1996/008864 WO1996039146A1 (en) 1995-06-06 1996-06-05 Non-irritation, non-sensitizing, non-ototoxic otic antibacterial compositions

Publications (1)

Publication Number Publication Date
DK0782448T3 true DK0782448T3 (da) 2002-07-08

Family

ID=23846298

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96917172T DK0782448T3 (da) 1995-06-06 1996-06-05 Ikke-irriterende, ikke-sensibiliserende, ikke-ototoksiske antibakterielle ørepræparater

Country Status (17)

Country Link
US (1) US5965549A (da)
EP (1) EP0782448B1 (da)
CN (1) CN1137685C (da)
AT (1) ATE214931T1 (da)
AU (1) AU708540B2 (da)
CA (1) CA2199294C (da)
DE (1) DE69620136T2 (da)
DK (1) DK0782448T3 (da)
ES (1) ES2173287T3 (da)
HK (1) HK1002552A1 (da)
IL (1) IL120317A (da)
MX (1) MX9701731A (da)
NZ (1) NZ309624A (da)
PT (1) PT782448E (da)
TW (1) TW464499B (da)
WO (1) WO1996039146A1 (da)
ZA (1) ZA964653B (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2344050A1 (en) * 1998-09-30 2000-04-06 Alcon Laboratories, Inc. Antibiotic compositions for treatment of the eye, ear and nose
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
US6395746B1 (en) * 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
AR020661A1 (es) * 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
US6500360B2 (en) * 1999-06-18 2002-12-31 Bernard Bendiner Sorbic acid and/or its derivatives, such as potassium sorbate, as a preventative for rust, corrosion and scale on metal surfaces
US6156294A (en) 1999-11-28 2000-12-05 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
US7064132B2 (en) * 1999-11-28 2006-06-20 Scientific Development And Research, Inc. Composition and method for treatment of otitis external
ES2160090B1 (es) * 2000-03-16 2002-07-01 Vita Invest Sa Composiciones acuosas de ciprofloxacino, contenidas en envases monodosis y su utilizacion.
AU2001276928A1 (en) * 2000-07-26 2002-02-05 Alcon Universal Ltd. Improved process for manufacturing compositions containing ciprofloxacin and hydrocortisone
HUP0303696A3 (en) 2000-09-25 2005-05-30 Bayer Healthcare Llc Tarrytown Otic microbial combinations for treatment of animals with ruptured tympanic membrane
BR0212898A (pt) 2001-09-21 2004-10-13 Alcon Inc Método de tratamento de infecções do ouvido médio
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
US20040101506A1 (en) * 2002-11-25 2004-05-27 Fust Charles A. Composition for the prevention and treatment of inflammation of the ear
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
US20050004098A1 (en) * 2003-03-20 2005-01-06 Britten Nancy Jean Dispersible formulation of an anti-inflammatory agent
MXPA05009978A (es) * 2003-03-20 2005-11-04 Pharmacia Corp Formulacion dispersable de un agente antiinflamatorio.
US20040214753A1 (en) * 2003-03-20 2004-10-28 Britten Nancy Jean Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
US20050009931A1 (en) * 2003-03-20 2005-01-13 Britten Nancy Jean Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
RU2329064C2 (ru) * 2003-07-31 2008-07-20 Фармация Энд Апджон Компани Ллс Диспергируемая фармацевтическая композиция для лечения мастита и поражений уха
KR100780983B1 (ko) * 2003-07-31 2007-11-30 파마시아 앤드 업존 캄파니 엘엘씨 소염제의 분산성 제제
US8940321B2 (en) 2003-12-12 2015-01-27 Otic Pharma Ltd. Compositions for treatment of ear disorders and methods of use thereof
ES2552936T3 (es) * 2003-12-12 2015-12-03 Otic Pharma Ltd. Composiciones para el tratamiento del desordenes en el oído y métodos para el uso de los mismos
US20060019987A1 (en) * 2004-07-23 2006-01-26 Fust Charles A Methods and compositions for inhibiting, destroying, and/or inactivating viruses
EP1962805B1 (en) 2005-12-08 2016-07-06 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections
US20100196455A1 (en) 2007-05-04 2010-08-05 Transave, Inc. Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
UA111147C2 (uk) * 2009-11-11 2016-04-11 Байєр Б.В. Способи та композиції для лікування або профілактики зовнішнього отиту
ES2391721T3 (es) 2010-03-01 2012-11-29 Laboratorios Salvat, S.A. Disoluciones acuosas transparentes de acetónido de fluocinolona para el tratamiento de la infamación de oído
HU227743B1 (en) * 2011-07-22 2012-02-28 Debreceni Egyetem Eardrop composition and process for producing this
BR112014013564A2 (pt) * 2011-12-09 2017-06-13 Lupin Ltd composição farmacêutica tópica destinada à aplicação ao olho, ouvido ou nariz
EP3581186A1 (en) 2012-11-29 2019-12-18 Insmed Incorporated Stabilized vancomycin formulations
US9895385B2 (en) 2014-05-15 2018-02-20 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
US9393243B1 (en) 2015-07-14 2016-07-19 Nilesh Parikh Topical Ciprofloxacin compositions
US11571386B2 (en) 2018-03-30 2023-02-07 Insmed Incorporated Methods for continuous manufacture of liposomal drug products

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4025620A (en) * 1975-10-22 1977-05-24 Leo Pharmaceutical Products Ltd., A/S Treatment of canine otitis and composition therefor
US4670444B1 (en) * 1980-09-03 1999-02-09 Bayer Ag and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds
ATE34720T1 (de) * 1983-03-31 1988-06-15 Payne Packaging Ltd Streifen.
DE3537761A1 (de) * 1985-10-24 1987-04-30 Bayer Ag Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure
DE3704907A1 (de) * 1987-02-17 1988-08-25 Bayer Ag Topisch anwendbare zubereitungen von gyrase-inhibitoren in kombination mit kortikosteroiden
DE3902079A1 (de) * 1988-04-15 1989-10-26 Bayer Ag I.m. injektionsformen von gyrase-inhibitoren
US5061729A (en) * 1988-06-08 1991-10-29 Biogal Gyogyszergyar Pharmaceutical composition and process for preparing the same
US5271939A (en) * 1988-10-03 1993-12-21 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation
US5260073A (en) * 1990-05-21 1993-11-09 Norwich Eaton Pharmaceuticals, Inc. Use of phenylpropanolamine as a mucus secretogogue in the upper airways
WO1994010976A1 (en) * 1992-11-16 1994-05-26 Ciba Vision Ag, Hettlingen Polyvinyl alcohol/borate ophthalmic drug delivery system
US5422116A (en) * 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system
ES2088742B1 (es) * 1994-06-29 1997-03-16 Salvat Lab Sa Composicion antibiotica de aplicacion otica.

Also Published As

Publication number Publication date
DE69620136D1 (de) 2002-05-02
US5965549A (en) 1999-10-12
CN1160999A (zh) 1997-10-01
ATE214931T1 (de) 2002-04-15
EP0782448B1 (en) 2002-03-27
IL120317A (en) 2000-08-13
CA2199294A1 (en) 1996-12-12
DE69620136T2 (de) 2002-08-01
EP0782448A1 (en) 1997-07-09
CN1137685C (zh) 2004-02-11
HK1002552A1 (en) 1998-09-04
AU5984096A (en) 1996-12-24
IL120317A0 (en) 1998-06-15
WO1996039146A1 (en) 1996-12-12
MX9701731A (es) 1997-10-31
NZ309624A (en) 1999-04-29
ZA964653B (en) 1996-12-12
PT782448E (pt) 2002-07-31
TW464499B (en) 2001-11-21
EP0782448A4 (en) 1998-05-20
CA2199294C (en) 2000-09-19
ES2173287T3 (es) 2002-10-16
AU708540B2 (en) 1999-08-05

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