ZA958688B - Methods for treating resistant tumors - Google Patents
Methods for treating resistant tumorsInfo
- Publication number
- ZA958688B ZA958688B ZA958688A ZA958688A ZA958688B ZA 958688 B ZA958688 B ZA 958688B ZA 958688 A ZA958688 A ZA 958688A ZA 958688 A ZA958688 A ZA 958688A ZA 958688 B ZA958688 B ZA 958688B
- Authority
- ZA
- South Africa
- Prior art keywords
- methods
- resistant tumors
- treating resistant
- treating
- tumors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32317694A | 1994-10-14 | 1994-10-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA958688B true ZA958688B (en) | 1997-04-14 |
Family
ID=23258042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA958688A ZA958688B (en) | 1994-10-14 | 1995-10-13 | Methods for treating resistant tumors |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US6124311A (hu) |
| EP (2) | EP0709090A3 (hu) |
| JP (1) | JPH10512544A (hu) |
| CN (1) | CN1168631A (hu) |
| AU (1) | AU702301B2 (hu) |
| CA (1) | CA2202661A1 (hu) |
| CZ (1) | CZ113797A3 (hu) |
| FI (1) | FI971568A (hu) |
| HU (1) | HUT77604A (hu) |
| IL (1) | IL115582A0 (hu) |
| MX (1) | MX9702700A (hu) |
| NO (1) | NO971704L (hu) |
| WO (1) | WO1996011677A1 (hu) |
| ZA (1) | ZA958688B (hu) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08253417A (ja) * | 1995-02-28 | 1996-10-01 | Eli Lilly & Co | 脳又はｃｎｓのエストロゲン陽性腫瘍抑制用製剤 |
| ZA961564B (en) * | 1995-02-28 | 1997-08-27 | Lilly Co Eli | Methods of inhibiting ovarian cancer. |
| EP0773217A1 (en) * | 1995-11-07 | 1997-05-14 | Eli Lilly And Company | Benzothiphene derivatives for treating resistant tumors |
| CA2206752A1 (en) * | 1996-07-02 | 1998-01-02 | George Joseph Cullinan | Benzothiophene compounds, intermediates, processes, and methods of use |
| CA2214922A1 (en) * | 1996-09-27 | 1998-03-27 | Eli Lilly And Company | Benzothiophene compounds, compositions, and methods |
| CA2275889C (en) | 1996-12-30 | 2008-03-18 | Battelle Memorial Institute | Formulation and method for treating neoplasms by inhalation |
| AU7274198A (en) | 1997-04-30 | 1998-11-24 | Eli Lilly And Company | Antithrombotic agents |
| CA2288144A1 (en) | 1997-04-30 | 1998-11-05 | Eli Lilly And Company | Antithrombotic agents |
| JP2002513415A (ja) | 1997-04-30 | 2002-05-08 | イーライ・リリー・アンド・カンパニー | 抗血栓剤 |
| AU7470098A (en) | 1997-04-30 | 1998-11-24 | Eli Lilly And Company | Antithrombotic agents |
| US5840721A (en) * | 1997-07-09 | 1998-11-24 | Ontogen Corporation | Imidazole derivatives as MDR modulators |
| US6284756B1 (en) | 1998-04-30 | 2001-09-04 | Eli Lilly And Company | Antithrombotic agents |
| CA2346029A1 (en) * | 1998-10-02 | 2000-04-13 | Anthony R. Imondi | Inhalation chemotherapy for prevention and treatment of metastatic tumors in the lung |
| CA2287549A1 (en) * | 1998-10-28 | 2000-04-28 | Jefferson Ray Mccowan | Antithrombotic agents |
| WO2000048541A1 (en) * | 1999-02-19 | 2000-08-24 | Brooks Norman A | Zinc chloride in treating skin diseases |
| WO2002020478A1 (en) * | 2000-08-24 | 2002-03-14 | Dublin City University | N-benzylindole-3-acetic acid derivatives for use in the treatment of drug resistan cancer |
| US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
| US7425565B2 (en) * | 2002-05-09 | 2008-09-16 | Cedars-Sinai Medical Center | Use of benzothiopenes to treat and prevent prostate cancer |
| US6630454B2 (en) * | 2001-09-10 | 2003-10-07 | Ramot At Tel-Aviv University Ltd. | Method and pharmaceutical composition for the treatment of cancer |
| AU2003256847A1 (en) * | 2002-07-26 | 2004-02-16 | Advanced Research And Technology Institute At Indiana University | Method of treating cancer |
| CN1281210C (zh) * | 2003-11-29 | 2006-10-25 | 胡汛 | 五味子乙素在制备治疗肿瘤药物中的应用 |
| US7781478B2 (en) * | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| KR20070083484A (ko) * | 2004-07-14 | 2007-08-24 | 피티씨 테라퓨틱스, 인크. | Ｃ형 간염 치료 방법 |
| US7772271B2 (en) * | 2004-07-14 | 2010-08-10 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| US7868037B2 (en) * | 2004-07-14 | 2011-01-11 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| NZ553329A (en) * | 2004-07-22 | 2010-09-30 | Ptc Therapeutics Inc | Thienopyridines for treating hepatitis C |
| FR2873692B1 (fr) * | 2004-07-29 | 2006-12-01 | Univ Claude Bernard Lyon | COMPOSITIONS CONTENANT, EN ASSOCIATION AVEC UN AGENT ANTIMICROBIEN, UN COMPOSE THIOPHENIQUE OU BENZOTHIOPHENIQUE DE FORMULE(I)PRESENTANT UNE ACTIVITE INHIBITRICE DE POMPE NorA |
| FR2913017A1 (fr) * | 2007-02-23 | 2008-08-29 | Cerep Sa | Derives de piperidine et piperazine comme agents anti-neoplasiques ou inhibiteurs de proliferation cellulaire |
| JP6807841B2 (ja) | 2014-12-18 | 2021-01-06 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | エストロゲン受容体モジュレーター及びその使用 |
| BR112017007662B1 (pt) * | 2014-12-18 | 2021-11-03 | F. Hoffmann-La Roche Ag | Composto, composição farmacêutica e uso de um composto |
| CN108129375B (zh) * | 2018-01-30 | 2020-04-28 | 中山大学 | 化合物及其制备方法与在制备肿瘤耐药逆转剂中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4133814A (en) | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
| US4230862A (en) | 1975-10-28 | 1980-10-28 | Eli Lilly And Company | Antifertility compounds |
| US4418068A (en) | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
| US4380635A (en) | 1981-04-03 | 1983-04-19 | Eli Lilly And Company | Synthesis of acylated benzothiophenes |
| US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| US5011472A (en) | 1988-09-06 | 1991-04-30 | Brown University Research Foundation | Implantable delivery system for biological factors |
| US5482949A (en) * | 1993-03-19 | 1996-01-09 | Eli Lilly And Company | Sulfonate derivatives of 3-aroylbenzo[b]thiophenes |
| IL111287A0 (en) * | 1993-10-15 | 1994-12-29 | Lilly Co Eli | Methods for treating resistant neoplasms |
| US5492927A (en) * | 1993-12-21 | 1996-02-20 | Eli Lilly And Company | Non-peptide tachykinin receptor antagonists to treat allergy |
| CA2176130A1 (en) * | 1993-12-21 | 1995-06-29 | Thomas Alan Crowell | Non-peptide tachykinin receptor antagonists |
| JPH09507071A (ja) * | 1993-12-21 | 1997-07-15 | イーライ・リリー・アンド・カンパニー | アミロイド原性ペプチドに関連した状態を治療又は予防する方法 |
-
1995
- 1995-10-12 IL IL11558295A patent/IL115582A0/xx unknown
- 1995-10-13 EP EP95307298A patent/EP0709090A3/en not_active Ceased
- 1995-10-13 EP EP97203340A patent/EP0820769A3/en not_active Withdrawn
- 1995-10-13 ZA ZA958688A patent/ZA958688B/xx unknown
- 1995-10-13 AU AU38298/95A patent/AU702301B2/en not_active Ceased
- 1995-10-13 MX MX9702700A patent/MX9702700A/es unknown
- 1995-10-13 JP JP8513362A patent/JPH10512544A/ja active Pending
- 1995-10-13 CA CA002202661A patent/CA2202661A1/en not_active Abandoned
- 1995-10-13 WO PCT/US1995/013036 patent/WO1996011677A1/en not_active Application Discontinuation
- 1995-10-13 CN CN95196608A patent/CN1168631A/zh active Pending
- 1995-10-13 CZ CZ971137A patent/CZ113797A3/cs unknown
- 1995-10-13 HU HU9702309A patent/HUT77604A/hu unknown
-
1996
- 1996-06-28 US US08/674,771 patent/US6124311A/en not_active Expired - Fee Related
- 1996-06-28 US US08/672,834 patent/US6121292A/en not_active Expired - Fee Related
-
1997
- 1997-04-14 NO NO971704A patent/NO971704L/no unknown
- 1997-04-14 FI FI971568A patent/FI971568A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT77604A (hu) | 1998-06-29 |
| EP0820769A3 (en) | 1998-08-19 |
| FI971568A (fi) | 1997-06-12 |
| NO971704L (no) | 1997-05-13 |
| EP0709090A3 (en) | 1996-08-28 |
| NO971704D0 (no) | 1997-04-14 |
| CA2202661A1 (en) | 1996-04-25 |
| MX9702700A (es) | 1997-06-28 |
| EP0820769A2 (en) | 1998-01-28 |
| US6121292A (en) | 2000-09-19 |
| AU702301B2 (en) | 1999-02-18 |
| AU3829895A (en) | 1996-05-06 |
| FI971568A0 (fi) | 1997-04-14 |
| CZ113797A3 (en) | 1997-09-17 |
| WO1996011677A1 (en) | 1996-04-25 |
| US6124311A (en) | 2000-09-26 |
| JPH10512544A (ja) | 1998-12-02 |
| IL115582A0 (en) | 1996-01-19 |
| CN1168631A (zh) | 1997-12-24 |
| EP0709090A2 (en) | 1996-05-01 |
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