ZA937483B - Process for the preparation of drug pellets - Google Patents

Process for the preparation of drug pellets

Info

Publication number
ZA937483B
ZA937483B ZA937483A ZA937483A ZA937483B ZA 937483 B ZA937483 B ZA 937483B ZA 937483 A ZA937483 A ZA 937483A ZA 937483 A ZA937483 A ZA 937483A ZA 937483 B ZA937483 B ZA 937483B
Authority
ZA
South Africa
Prior art keywords
preparation
drug pellets
pellets
drug
Prior art date
Application number
ZA937483A
Other languages
English (en)
Inventor
Leena Hellen
Isabelle Husson
Eeva Kristoffersson
Jouko Yliruusi
Original Assignee
Leena Hellen
Isabelle Husson
Eeva Kristoffersson
Jouko Yliruusi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leena Hellen, Isabelle Husson, Eeva Kristoffersson, Jouko Yliruusi filed Critical Leena Hellen
Publication of ZA937483B publication Critical patent/ZA937483B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/003Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic followed by coating of the granules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/10Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic in stationary drums or troughs, provided with kneading or mixing appliances
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/30Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using agents to prevent the granules sticking together; Rendering particulate materials free flowing in general, e.g. making them hydrophobic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
ZA937483A 1992-10-09 1993-10-08 Process for the preparation of drug pellets ZA937483B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI924590A FI101039B (fi) 1992-10-09 1992-10-09 Menetelmä lääkepellettien valmistamiseksi

Publications (1)

Publication Number Publication Date
ZA937483B true ZA937483B (en) 1994-04-26

Family

ID=8536020

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA937483A ZA937483B (en) 1992-10-09 1993-10-08 Process for the preparation of drug pellets

Country Status (9)

Country Link
US (1) US5709885A (fr)
EP (1) EP0662823A1 (fr)
JP (1) JPH08502675A (fr)
AU (1) AU5112993A (fr)
CA (1) CA2146536A1 (fr)
FI (1) FI101039B (fr)
NO (1) NO951370L (fr)
WO (1) WO1994008567A1 (fr)
ZA (1) ZA937483B (fr)

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WO2000045734A1 (fr) 1999-02-02 2000-08-10 Wright Medical Technology, Inc. Composite à libération contrôlée
GEP20043285B (en) 2000-03-30 2004-07-26 Bristol Myers Squibb Co Sustained Release Beadlets Containing Stavudine, Method for Their Production, Pharmaceutical Composition Containing the Same and Use Thereof for Treatment Retroviral Infections
FR2814366A1 (fr) * 2000-09-22 2002-03-29 Rhodia Chimie Sa Procede de granulation de matieres actives par extrusion basse pression pour l'obtention de granules directement compressibles
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
KR100510270B1 (ko) * 2002-11-29 2005-08-26 센츄론(주) 펠렛타이저를 이용한 서방성 제제의 제조방법
US9107804B2 (en) * 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102004032051A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
WO2005123042A1 (fr) * 2004-06-10 2005-12-29 Glatt Air Techniques, Inc. Preparation pharmaceutique a liberation lente
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
EP2050447B1 (fr) * 2005-06-08 2017-10-11 Orion Corporation Formule de dosage oral contenant entacapone
US20070036859A1 (en) * 2005-08-11 2007-02-15 Perry Ronald L Sustained release antihistamine and decongestant composition
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
BRPI0906467C1 (pt) 2008-01-25 2021-05-25 Gruenenthal Gmbh forma de dosagem farmacêutica com formato exterior modificado resistente à ruptura e com liberação controlada
KR101690094B1 (ko) 2008-05-09 2016-12-27 그뤼넨탈 게엠베하 분무 응결 단계의 사용하에 중간 분말 제형 및 최종 고체 제형을 제조하는 방법
CN101744725B (zh) * 2008-12-09 2013-04-17 北京华素制药股份有限公司 缓释微丸包衣生产工艺参数的优化方法
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
WO2011009604A1 (fr) 2009-07-22 2011-01-27 Grünenthal GmbH Forme galénique inviolable stabilisée à l’oxydation
PE20121067A1 (es) 2009-07-22 2012-09-05 Gruenenthal Chemie Forma de dosificacion de liberacion controlada extruida por fusion en caliente
WO2012028319A1 (fr) 2010-09-02 2012-03-08 Grünenthal GmbH Forme pharmaceutique inviolable comportant un sel inorganique
CA2808541C (fr) 2010-09-02 2019-01-08 Gruenenthal Gmbh Forme pharmaceutique inviolable comportant un polymere anionique
AR087360A1 (es) 2011-07-29 2014-03-19 Gruenenthal Gmbh Tableta a prueba de manipulacion que proporciona liberacion de farmaco inmediato
KR20140053158A (ko) 2011-07-29 2014-05-07 그뤼넨탈 게엠베하 즉시 약물 방출을 제공하는 탬퍼-저항성 정제
CA2864949A1 (fr) 2012-02-28 2013-09-06 Grunenthal Gmbh Forme pharmaceutique inviolable comprenant un compose pharmacologiquement actif et un polymere anionique
JP6282261B2 (ja) 2012-04-18 2018-02-21 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 不正使用防止および過量放出防止医薬剤形
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
CA2913209A1 (fr) 2013-05-29 2014-12-04 Grunenthal Gmbh Forme dosifiee inviolable a profil de liberation bimodale
EP3003279A1 (fr) 2013-05-29 2016-04-13 Grünenthal GmbH Forme pharmaceutique inviolable contenant une ou plusieurs particules
AU2014289187B2 (en) 2013-07-12 2019-07-11 Grunenthal Gmbh Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
MX371372B (es) 2013-11-26 2020-01-28 Gruenenthal Gmbh Preparacion de una composicion farmaceutica en polvo por medio de criomolienda.
CA2947786A1 (fr) 2014-05-12 2015-11-19 Grunenthal Gmbh Formulation pour capsule a liberation immediate resistant aux manipulations illicites comprenant du tapentadol
WO2015181059A1 (fr) 2014-05-26 2015-12-03 Grünenthal GmbH Microparticules protégées contre une libération massive dans l'éthanol
SG10201912145VA (en) 2014-06-04 2020-02-27 Dignity Sciences Ltd Pharmaceutical compositions comprising dgla and use of same
JP2018517676A (ja) 2015-04-24 2018-07-05 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 即時放出および溶媒抽出に対する耐性を有する改変防止製剤
WO2017042325A1 (fr) 2015-09-10 2017-03-16 Grünenthal GmbH Protection contre un surdosage par voie orale à l'aide de formulations à libération immédiate dissuasives d'abus
JP2017132716A (ja) * 2016-01-27 2017-08-03 ライオン株式会社 錠剤の製造方法
CN109925290B (zh) * 2017-12-18 2021-03-16 广州白云山明兴制药有限公司 茶碱缓释片及其制备工艺
US20210315851A1 (en) 2020-04-03 2021-10-14 Afimmune Limited Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases
CN116474715A (zh) * 2022-01-15 2023-07-25 中国石油化工股份有限公司 一种球形材料及其制备方法

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FR2470599A1 (fr) * 1979-12-07 1981-06-12 Panoz Donald Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus
JPS5949840A (ja) * 1982-09-14 1984-03-22 Taiyo Yakuhin Kogyo Kk 顆粒、細粒の固着防止方法
GB8519310D0 (en) * 1985-07-31 1985-09-04 Zyma Sa Granular active substances
GB8702411D0 (en) * 1987-02-03 1987-03-11 Zyma Sa Swellable pellets
HU206828B (en) * 1989-08-10 1993-01-28 Chinoin Gyogyszer Es Vegyeszet Process for producing veterinary compositions containing benzimidazol derivatives as active components
DK162506C (da) * 1989-12-22 1992-03-30 Ferrosan As Fremgangsmaade til fremstilling af et tabletterbart granulat
IT1243390B (it) * 1990-11-22 1994-06-10 Vectorpharma Int Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione.
GB9119052D0 (en) * 1991-09-06 1991-10-23 Boots Co Plc Pharmaceutical compositions
WO1993007859A1 (fr) * 1991-10-23 1993-04-29 Warner-Lambert Company Nouveaux granules pharmaceutiques et procede de preparation

Also Published As

Publication number Publication date
NO951370D0 (no) 1995-04-07
CA2146536A1 (fr) 1994-04-28
FI924590A0 (fi) 1992-10-09
US5709885A (en) 1998-01-20
JPH08502675A (ja) 1996-03-26
AU5112993A (en) 1994-05-09
FI924590A (fi) 1994-04-10
WO1994008567A1 (fr) 1994-04-28
NO951370L (no) 1995-06-08
EP0662823A1 (fr) 1995-07-19
FI101039B (fi) 1998-04-15

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