ZA937241B - 5h, 10h-imidazo(,2-a) indeno(1,2-e)pyrazin-4-one derivatives their preparation and medicinal products containing them - Google Patents
5h, 10h-imidazo(,2-a) indeno(1,2-e)pyrazin-4-one derivatives their preparation and medicinal products containing themInfo
- Publication number
- ZA937241B ZA937241B ZA937241A ZA937241A ZA937241B ZA 937241 B ZA937241 B ZA 937241B ZA 937241 A ZA937241 A ZA 937241A ZA 937241 A ZA937241 A ZA 937241A ZA 937241 B ZA937241 B ZA 937241B
- Authority
- ZA
- South Africa
- Prior art keywords
- pct
- preparation
- indeno
- pyrazin
- imidazo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9211674A FR2696466B1 (fr) | 1992-10-02 | 1992-10-02 | Dérivés de 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant. |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA937241B true ZA937241B (en) | 1994-04-19 |
Family
ID=9434062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA937241A ZA937241B (en) | 1992-10-02 | 1993-09-29 | 5h, 10h-imidazo(,2-a) indeno(1,2-e)pyrazin-4-one derivatives their preparation and medicinal products containing them |
Country Status (16)
Country | Link |
---|---|
US (1) | US5677306A (xx) |
EP (1) | EP0662971B1 (xx) |
JP (1) | JPH08501786A (xx) |
AT (1) | ATE166055T1 (xx) |
AU (1) | AU672817B2 (xx) |
CA (1) | CA2146152A1 (xx) |
DE (1) | DE69318563T2 (xx) |
DK (1) | DK0662971T3 (xx) |
ES (1) | ES2116467T3 (xx) |
FI (1) | FI951555A0 (xx) |
FR (1) | FR2696466B1 (xx) |
HU (1) | HUT72501A (xx) |
NZ (1) | NZ256055A (xx) |
PL (1) | PL308232A1 (xx) |
WO (1) | WO1994007893A1 (xx) |
ZA (1) | ZA937241B (xx) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2707643B1 (fr) * | 1993-07-16 | 1995-08-11 | Rhone Poulenc Rorer Sa | Dérivés d'imidazo[1,2-a]pyrazine-4-one, leur préparation et les médicaments les contenant. |
FR2711993B1 (fr) * | 1993-11-05 | 1995-12-01 | Rhone Poulenc Rorer Sa | Médicaments contenant des dérivés de 7H-imidazol[1,2-a]pyrazine-8-one, les nouveaux composés et leur préparation. |
FR2717813B1 (fr) * | 1994-03-28 | 1996-05-10 | Rhone Poulenc Rorer Sa | Dérivés d'imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant . |
FR2717811B1 (fr) * | 1994-03-28 | 1996-04-26 | Rhone Poulenc Rorer Sa | Dérivés d'imidazo[1,2-a]pyrazine-4-one, leur préparation et les médicaments les contenant. |
FR2717805B1 (fr) * | 1994-03-28 | 1996-05-10 | Rhone Poulenc Rorer Sa | Dérivés de 5H-indeno[1,2-b]pyrazine-2,3-dione, leur préparation et les médicaments les contenant . |
FR2717814B1 (fr) * | 1994-03-28 | 1996-04-26 | Rhone Poulenc Rorer Sa | Dérivés de 1,2,4-triazolo(4,3-a)pyrazine-4-one, leur préparation et les médicaments les contenant. |
FR2717812B1 (fr) * | 1994-03-28 | 1996-05-10 | Rhone Poulenc Rorer Sa | Indeno[1,2-e]pyrazine-4-ones, leur préparation et les médicaments les contenant. |
FR2722789B1 (fr) * | 1994-07-20 | 1996-08-23 | Rhone Poulenc Rorer Sa | Derives d'acide imidazo (1,2-a)indeno(1,2-e) pyrazine-2-carboxylique, leur preparation et les medicaments les contenant |
FR2726275B1 (fr) * | 1994-11-02 | 1996-12-06 | Rhone Poulenc Rorer Sa | Spiro heterocycle-imidazo(1,2-a)indeno(1,2-e)pyrazine)-4'- ones, leur preparation et les medicaments les contenants |
FR2732681B1 (fr) * | 1995-04-05 | 1997-07-04 | Rhone Poulenc Rorer Sa | Derives de 10h-imidazo(1,2-a)indeno(1,2-e)pyrazin-4-one, leur preparation et les medicaments les contenant |
FR2743363A1 (fr) * | 1996-01-10 | 1997-07-11 | Rhone Poulenc Rorer Sa | 5h,10h-imidazo(1,2-a)indeno(1,2-e)pyrazine-a-ones substituees en position 2, leur preparation et les medicaments les contenant |
US6869956B2 (en) | 2000-10-03 | 2005-03-22 | Bristol-Myers Squibb Company | Methods of treating inflammatory and immune diseases using inhibitors of IκB kinase (IKK) |
US6960585B2 (en) | 2000-10-03 | 2005-11-01 | Bristol-Myers Squibb Company | Amino-substituted tetracyclic compounds useful as anti-inflammatory agents and pharmaceutical compositions comprising same |
US6956129B2 (en) * | 2001-02-16 | 2005-10-18 | Bayer Aktiengesellschaft | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4242344A (en) * | 1979-01-22 | 1980-12-30 | Merck & Co., Inc. | Piperazinyl-imidazo[1,2-a]pyrazines |
ATE2004T1 (de) * | 1979-01-22 | 1982-12-15 | Merck & Co. Inc. | Piperazinyl-imidazo(1,2-a)pyrazin-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. |
US4354027A (en) * | 1980-05-19 | 1982-10-12 | Usv Pharmaceutical Corporation | Triazoloquinoxalin-4-ones |
FI823156L (fi) * | 1981-09-16 | 1983-03-17 | Ciba Geigy Ag | Foerfarande foer framstaellning av nya polycykliska polyazaheterocykler |
NO179551C (no) * | 1987-11-10 | 1996-10-30 | Novo Nordisk As | Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser |
DK626288D0 (da) * | 1988-11-10 | 1988-11-10 | Ferrosan As | Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processen |
DK69790D0 (da) * | 1990-03-16 | 1990-03-16 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling af anvendelse |
DK101290D0 (da) * | 1990-04-24 | 1990-04-24 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
JPH04178385A (ja) * | 1990-11-09 | 1992-06-25 | Yamanouchi Pharmaceut Co Ltd | ジケトピリドピラジン誘導体 |
GB9109972D0 (en) * | 1991-05-09 | 1991-07-03 | Ici Plc | Therapeutic compounds |
US5306819A (en) * | 1992-08-27 | 1994-04-26 | Neurogen Corporation | Certain aryl a cycloalkyl fused imidazopyrazinols; and new class of GABA brain receptor ligands |
-
1992
- 1992-10-02 FR FR9211674A patent/FR2696466B1/fr not_active Expired - Fee Related
-
1993
- 1993-09-28 AU AU48242/93A patent/AU672817B2/en not_active Ceased
- 1993-09-28 US US08/406,982 patent/US5677306A/en not_active Expired - Fee Related
- 1993-09-28 PL PL93308232A patent/PL308232A1/xx unknown
- 1993-09-28 CA CA002146152A patent/CA2146152A1/fr not_active Abandoned
- 1993-09-28 HU HU9500959A patent/HUT72501A/hu unknown
- 1993-09-28 ES ES93920940T patent/ES2116467T3/es not_active Expired - Lifetime
- 1993-09-28 DK DK93920940T patent/DK0662971T3/da active
- 1993-09-28 EP EP93920940A patent/EP0662971B1/fr not_active Expired - Lifetime
- 1993-09-28 NZ NZ256055A patent/NZ256055A/en unknown
- 1993-09-28 DE DE69318563T patent/DE69318563T2/de not_active Expired - Fee Related
- 1993-09-28 AT AT93920940T patent/ATE166055T1/de not_active IP Right Cessation
- 1993-09-28 WO PCT/FR1993/000946 patent/WO1994007893A1/fr active IP Right Grant
- 1993-09-28 JP JP6508775A patent/JPH08501786A/ja active Pending
- 1993-09-29 ZA ZA937241A patent/ZA937241B/xx unknown
-
1995
- 1995-03-31 FI FI951555A patent/FI951555A0/fi unknown
Also Published As
Publication number | Publication date |
---|---|
EP0662971B1 (fr) | 1998-05-13 |
FR2696466B1 (fr) | 1994-11-25 |
US5677306A (en) | 1997-10-14 |
FR2696466A1 (fr) | 1994-04-08 |
EP0662971A1 (fr) | 1995-07-19 |
AU672817B2 (en) | 1996-10-17 |
AU4824293A (en) | 1994-04-26 |
DK0662971T3 (da) | 1998-10-07 |
ES2116467T3 (es) | 1998-07-16 |
CA2146152A1 (fr) | 1994-04-14 |
JPH08501786A (ja) | 1996-02-27 |
PL308232A1 (en) | 1995-07-24 |
HU9500959D0 (en) | 1995-05-29 |
FI951555A (fi) | 1995-03-31 |
HUT72501A (en) | 1996-05-28 |
DE69318563T2 (de) | 1998-11-26 |
ATE166055T1 (de) | 1998-05-15 |
WO1994007893A1 (fr) | 1994-04-14 |
DE69318563D1 (de) | 1998-06-18 |
NZ256055A (en) | 1996-09-25 |
FI951555A0 (fi) | 1995-03-31 |
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