FI951555A0 - 5H,10H-imidatso[1,2-a]indeno[1,2-e]pyratsin-4-onijohdannaiset, niiden valmistus ja niitä sisältävät lääkkeet - Google Patents

5H,10H-imidatso[1,2-a]indeno[1,2-e]pyratsin-4-onijohdannaiset, niiden valmistus ja niitä sisältävät lääkkeet

Info

Publication number
FI951555A0
FI951555A0 FI951555A FI951555A FI951555A0 FI 951555 A0 FI951555 A0 FI 951555A0 FI 951555 A FI951555 A FI 951555A FI 951555 A FI951555 A FI 951555A FI 951555 A0 FI951555 A0 FI 951555A0
Authority
FI
Finland
Prior art keywords
pct
preparation
indeno
pyrazin
imidazo
Prior art date
Application number
FI951555A
Other languages
English (en)
Swedish (sv)
Other versions
FI951555A (fi
Inventor
Jean-Claude Aloup
Francois Audiau
Dominique Damour
Arielle Genevois-Borella
Patrick Jimonet
Serge Mignani
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI951555A publication Critical patent/FI951555A/fi
Publication of FI951555A0 publication Critical patent/FI951555A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
FI951555A 1992-10-02 1995-03-31 5H,10H-imidatso[1,2-a]indeno[1,2-e]pyratsin-4-onijohdannaiset, niiden valmistus ja niitä sisältävät lääkkeet FI951555A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9211674A FR2696466B1 (fr) 1992-10-02 1992-10-02 Dérivés de 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant.
PCT/FR1993/000946 WO1994007893A1 (fr) 1992-10-02 1993-09-28 DERIVES DE 5H,10H-IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZINE-4-ONE, LEUR PREPARATION ET LES MEDICAMENTS LES CONTENANT

Publications (2)

Publication Number Publication Date
FI951555A FI951555A (fi) 1995-03-31
FI951555A0 true FI951555A0 (fi) 1995-03-31

Family

ID=9434062

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951555A FI951555A0 (fi) 1992-10-02 1995-03-31 5H,10H-imidatso[1,2-a]indeno[1,2-e]pyratsin-4-onijohdannaiset, niiden valmistus ja niitä sisältävät lääkkeet

Country Status (16)

Country Link
US (1) US5677306A (fi)
EP (1) EP0662971B1 (fi)
JP (1) JPH08501786A (fi)
AT (1) ATE166055T1 (fi)
AU (1) AU672817B2 (fi)
CA (1) CA2146152A1 (fi)
DE (1) DE69318563T2 (fi)
DK (1) DK0662971T3 (fi)
ES (1) ES2116467T3 (fi)
FI (1) FI951555A0 (fi)
FR (1) FR2696466B1 (fi)
HU (1) HUT72501A (fi)
NZ (1) NZ256055A (fi)
PL (1) PL308232A1 (fi)
WO (1) WO1994007893A1 (fi)
ZA (1) ZA937241B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707643B1 (fr) * 1993-07-16 1995-08-11 Rhone Poulenc Rorer Sa Dérivés d'imidazo[1,2-a]pyrazine-4-one, leur préparation et les médicaments les contenant.
FR2711993B1 (fr) * 1993-11-05 1995-12-01 Rhone Poulenc Rorer Sa Médicaments contenant des dérivés de 7H-imidazol[1,2-a]pyrazine-8-one, les nouveaux composés et leur préparation.
FR2717813B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Dérivés d'imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant .
FR2717814B1 (fr) * 1994-03-28 1996-04-26 Rhone Poulenc Rorer Sa Dérivés de 1,2,4-triazolo(4,3-a)pyrazine-4-one, leur préparation et les médicaments les contenant.
FR2717811B1 (fr) * 1994-03-28 1996-04-26 Rhone Poulenc Rorer Sa Dérivés d'imidazo[1,2-a]pyrazine-4-one, leur préparation et les médicaments les contenant.
FR2717805B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Dérivés de 5H-indeno[1,2-b]pyrazine-2,3-dione, leur préparation et les médicaments les contenant .
FR2717812B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Indeno[1,2-e]pyrazine-4-ones, leur préparation et les médicaments les contenant.
FR2722789B1 (fr) * 1994-07-20 1996-08-23 Rhone Poulenc Rorer Sa Derives d'acide imidazo (1,2-a)indeno(1,2-e) pyrazine-2-carboxylique, leur preparation et les medicaments les contenant
FR2726275B1 (fr) * 1994-11-02 1996-12-06 Rhone Poulenc Rorer Sa Spiro heterocycle-imidazo(1,2-a)indeno(1,2-e)pyrazine)-4'- ones, leur preparation et les medicaments les contenants
FR2732681B1 (fr) * 1995-04-05 1997-07-04 Rhone Poulenc Rorer Sa Derives de 10h-imidazo(1,2-a)indeno(1,2-e)pyrazin-4-one, leur preparation et les medicaments les contenant
FR2743363A1 (fr) * 1996-01-10 1997-07-11 Rhone Poulenc Rorer Sa 5h,10h-imidazo(1,2-a)indeno(1,2-e)pyrazine-a-ones substituees en position 2, leur preparation et les medicaments les contenant
ES2260300T3 (es) 2000-10-03 2006-11-01 Bristol-Myers Squibb Company Compuestos tetraciclicos sustituidos con amino utiles como agentes antiinflamatorios y composiciones farmaceuticas que comprenden los mismos.
US6869956B2 (en) 2000-10-03 2005-03-22 Bristol-Myers Squibb Company Methods of treating inflammatory and immune diseases using inhibitors of IκB kinase (IKK)
US6956129B2 (en) * 2001-02-16 2005-10-18 Bayer Aktiengesellschaft Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242344A (en) * 1979-01-22 1980-12-30 Merck & Co., Inc. Piperazinyl-imidazo[1,2-a]pyrazines
DE3061283D1 (en) * 1979-01-22 1983-01-20 Merck & Co Inc Piperazinyl-imidazo(1,2-a)pyrazine derivatives, process for their preparation and pharmaceutical compositions containing them
US4354027A (en) * 1980-05-19 1982-10-12 Usv Pharmaceutical Corporation Triazoloquinoxalin-4-ones
FI823156L (fi) * 1981-09-16 1983-03-17 Ciba Geigy Ag Foerfarande foer framstaellning av nya polycykliska polyazaheterocykler
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK626288D0 (da) * 1988-11-10 1988-11-10 Ferrosan As Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processen
DK69790D0 (da) * 1990-03-16 1990-03-16 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling af anvendelse
DK101290D0 (da) * 1990-04-24 1990-04-24 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
JPH04178385A (ja) * 1990-11-09 1992-06-25 Yamanouchi Pharmaceut Co Ltd ジケトピリドピラジン誘導体
GB9109972D0 (en) * 1991-05-09 1991-07-03 Ici Plc Therapeutic compounds
US5306819A (en) * 1992-08-27 1994-04-26 Neurogen Corporation Certain aryl a cycloalkyl fused imidazopyrazinols; and new class of GABA brain receptor ligands

Also Published As

Publication number Publication date
WO1994007893A1 (fr) 1994-04-14
DE69318563T2 (de) 1998-11-26
HU9500959D0 (en) 1995-05-29
AU672817B2 (en) 1996-10-17
FR2696466B1 (fr) 1994-11-25
JPH08501786A (ja) 1996-02-27
ATE166055T1 (de) 1998-05-15
EP0662971B1 (fr) 1998-05-13
ES2116467T3 (es) 1998-07-16
NZ256055A (en) 1996-09-25
CA2146152A1 (fr) 1994-04-14
US5677306A (en) 1997-10-14
FI951555A (fi) 1995-03-31
HUT72501A (en) 1996-05-28
DE69318563D1 (de) 1998-06-18
EP0662971A1 (fr) 1995-07-19
FR2696466A1 (fr) 1994-04-08
AU4824293A (en) 1994-04-26
DK0662971T3 (da) 1998-10-07
PL308232A1 (en) 1995-07-24
ZA937241B (en) 1994-04-19

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