ZA934584B - Imidazolyl-substituted phenylpropionic and cinnamic acid derivatives - Google Patents

Imidazolyl-substituted phenylpropionic and cinnamic acid derivatives

Info

Publication number
ZA934584B
ZA934584B ZA934584A ZA934584A ZA934584B ZA 934584 B ZA934584 B ZA 934584B ZA 934584 A ZA934584 A ZA 934584A ZA 934584 A ZA934584 A ZA 934584A ZA 934584 B ZA934584 B ZA 934584B
Authority
ZA
South Africa
Prior art keywords
imidazolyl
acid derivatives
cinnamic acid
substituted phenylpropionic
phenylpropionic
Prior art date
Application number
ZA934584A
Other languages
English (en)
Inventor
Ulrich E Mueller
Juergen Dressel
Peter Fey
Rudolf H Hanko
Walter Huebsch
Thomas Kramer
Matthias Mueller-Gliemann
Martin Beuck
Stanislav Kazda
Andreas Knorr
Johannes-Peter Stasch
Stefan Wohlfeil
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA934584B publication Critical patent/ZA934584B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
ZA934584A 1992-06-26 1993-06-25 Imidazolyl-substituted phenylpropionic and cinnamic acid derivatives ZA934584B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4220983A DE4220983A1 (de) 1992-06-26 1992-06-26 Imidazolyl-substituierte Phenylpropion- und -zimtsäurederivate

Publications (1)

Publication Number Publication Date
ZA934584B true ZA934584B (en) 1994-02-01

Family

ID=6461888

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA934584A ZA934584B (en) 1992-06-26 1993-06-25 Imidazolyl-substituted phenylpropionic and cinnamic acid derivatives

Country Status (17)

Country Link
US (1) US5414008A (xx)
EP (1) EP0578002A1 (xx)
JP (1) JPH0665209A (xx)
KR (1) KR940000434A (xx)
CN (1) CN1082041A (xx)
AU (1) AU4006393A (xx)
CA (1) CA2099068A1 (xx)
CZ (1) CZ117493A3 (xx)
DE (1) DE4220983A1 (xx)
FI (1) FI932953A (xx)
HU (1) HUT65190A (xx)
IL (1) IL106108A0 (xx)
MX (1) MX9303600A (xx)
NO (1) NO932132L (xx)
SK (1) SK66793A3 (xx)
TW (1) TW239132B (xx)
ZA (1) ZA934584B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69739181D1 (de) * 1996-08-12 2009-02-05 Celgene Corp Neue immunotherapeutische Mittel und deren Verwendung in der Reduzierung von Cytokinenspiegel
US7165676B2 (en) * 2002-04-19 2007-01-23 Smurfit-Stone Container Enterprises, Inc. Heat seal blister package having improved moisture vapor transmission barrier and method for forming same
US7470723B2 (en) * 2003-03-05 2008-12-30 Celgene Corporation Diphenylethylene compounds and uses thereof
CN101053558A (zh) * 2003-03-05 2007-10-17 细胞基因公司 二苯基乙烯化合物及其用途
WO2006028963A2 (en) * 2004-09-03 2006-03-16 Celgene Corporation Substituted heterocyclic compounds and uses thereof
JP2010502706A (ja) * 2006-09-07 2010-01-28 ミレニアム・ファーマシューティカルズ・インコーポレイテッド キナーゼ阻害活性を有するフェネチルアミド誘導体
PT3307739T (pt) * 2015-06-15 2021-01-04 Glaxosmithkline Ip Dev Ltd Reguladores de nrf2
CN115557898A (zh) * 2021-07-01 2023-01-03 诸葛国琴 一种咪唑类化合物、其中间体及应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55313A (en) * 1978-06-13 1980-01-05 Kissei Pharmaceut Co Ltd Imidazole derivative
JPS5671074A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative
DE3130254A1 (de) * 1981-07-31 1983-02-17 A. Nattermann & Cie GmbH, 5000 Köln (omega)-(4-((omega)'-(1-imidazolyl)-alkyl)-phenyl)-(omega)-oxo-alkancarbonsaeuren und deren derivae, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3424944A1 (de) * 1984-07-06 1986-02-06 Hoechst Ag, 6230 Frankfurt Neue imidazolyverbindungen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
DE3800785A1 (de) * 1988-01-09 1989-07-20 Hoechst Ag Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
US5183810A (en) * 1990-02-13 1993-02-02 Merck & Co., Inc. Imidazole angiotensin II antagonists incorporating a substituted benzyl element
JP2626167B2 (ja) * 1990-05-18 1997-07-02 日産自動車株式会社 四輪駆動車のトランスファー装置

Also Published As

Publication number Publication date
CZ117493A3 (en) 1994-01-19
CA2099068A1 (en) 1993-12-27
DE4220983A1 (de) 1994-01-05
IL106108A0 (en) 1993-10-20
AU4006393A (en) 1994-01-06
NO932132D0 (no) 1993-06-10
MX9303600A (es) 1993-12-01
HUT65190A (en) 1994-05-02
FI932953A0 (fi) 1993-06-24
NO932132L (no) 1993-12-27
KR940000434A (ko) 1994-01-03
EP0578002A1 (de) 1994-01-12
HU9301871D0 (en) 1993-09-28
TW239132B (xx) 1995-01-21
CN1082041A (zh) 1994-02-16
SK66793A3 (en) 1994-02-02
FI932953A (fi) 1993-12-27
US5414008A (en) 1995-05-09
JPH0665209A (ja) 1994-03-08

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