ZA932523B - Immunotoxins directed against cd33 related surface antigens - Google Patents

Immunotoxins directed against cd33 related surface antigens

Info

Publication number
ZA932523B
ZA932523B ZA932523A ZA932523A ZA932523B ZA 932523 B ZA932523 B ZA 932523B ZA 932523 A ZA932523 A ZA 932523A ZA 932523 A ZA932523 A ZA 932523A ZA 932523 B ZA932523 B ZA 932523B
Authority
ZA
South Africa
Prior art keywords
directed against
surface antigens
related surface
immunotoxins directed
immunotoxins
Prior art date
Application number
ZA932523A
Other languages
English (en)
Inventor
Michael G Rosenblum
Original Assignee
Res Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Dev Foundation filed Critical Res Dev Foundation
Publication of ZA932523B publication Critical patent/ZA932523B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/01Hydrolysed proteins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6425Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA932523A 1992-04-10 1993-01-01 Immunotoxins directed against cd33 related surface antigens ZA932523B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86669392A 1992-04-10 1992-04-10

Publications (1)

Publication Number Publication Date
ZA932523B true ZA932523B (en) 1994-10-08

Family

ID=25348185

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA932523A ZA932523B (en) 1992-04-10 1993-01-01 Immunotoxins directed against cd33 related surface antigens

Country Status (13)

Country Link
EP (2) EP0634938A4 (de)
JP (1) JP3949158B2 (de)
KR (1) KR950700760A (de)
CN (1) CN1056084C (de)
AU (1) AU675226B2 (de)
CA (1) CA2133838C (de)
FI (1) FI944730A (de)
IL (1) IL105344A (de)
NO (1) NO314686B1 (de)
NZ (1) NZ252799A (de)
RU (1) RU2127122C1 (de)
WO (1) WO1993020848A1 (de)
ZA (1) ZA932523B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6599505B1 (en) 1992-04-10 2003-07-29 Research Development Foundation Immunotoxins directed against CD33 related surface antigens
IL112372A (en) * 1994-02-07 2001-08-26 Res Dev Foundation Non-viral vector for the delivery of genetic information to cells
AUPN115095A0 (en) * 1995-02-15 1995-03-09 Butt, Henry Lawrence Analysis of and compositions and methods for the treatment of disease
KR101021124B1 (ko) * 2001-05-24 2011-03-14 지모제넥틱스, 인코포레이티드 Taci-면역글로불린 융합 단백질
TW200726776A (en) * 2005-07-29 2007-07-16 Friedrich Alexander University Of Erlangen Nuremberg CD33-specific single-chain immunotoxin and methods of use
DE102009045006A1 (de) 2009-09-25 2011-04-14 Technische Universität Dresden Anti-CD33 Antikörper und ihre Anwendung zum Immunotargeting bei der Behandlung von CD33-assoziierten Erkrankungen
UA112062C2 (uk) 2010-10-04 2016-07-25 Бьорінгер Інгельхайм Інтернаціональ Гмбх Cd33-зв'язувальний агент
EP2777714A1 (de) 2013-03-15 2014-09-17 NBE-Therapeutics LLC Verfahren zur Herstellung eines Immunoliganden/Nutzlastkonjugats durch ein Sequenz-spezifisches Transpeptidase Enzym
JP7497953B2 (ja) 2015-06-12 2024-06-11 アレクトル エルエルシー 抗cd33抗体及びその使用方法
CN116063499A (zh) * 2015-06-12 2023-05-05 艾利妥 抗cd33抗体及其使用方法
WO2019028283A1 (en) 2017-08-03 2019-02-07 Alector Llc ANTI-CD33 ANTIBODIES AND METHODS OF USE
CN113801229A (zh) 2018-08-31 2021-12-17 艾利妥 抗cd33抗体及其使用方法
WO2023081898A1 (en) 2021-11-08 2023-05-11 Alector Llc Soluble cd33 as a biomarker for anti-cd33 efficacy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE62463B1 (en) * 1988-07-07 1995-02-08 Res Dev Foundation Immunoconjugates for cancer diagnosis and therapy
WO1991009058A1 (en) * 1989-12-14 1991-06-27 Sloan-Kettering Institute For Cancer Research Therapeutic uses of the hypervariable region of monoclonal antibody m195 and constructs thereof

Also Published As

Publication number Publication date
JPH08501059A (ja) 1996-02-06
FI944730A0 (fi) 1994-10-07
JP3949158B2 (ja) 2007-07-25
KR950700760A (ko) 1995-02-20
EP0634938A1 (de) 1995-01-25
FI944730A (fi) 1994-10-07
AU675226B2 (en) 1997-01-30
CN1078401A (zh) 1993-11-17
IL105344A0 (en) 1993-08-18
CN1056084C (zh) 2000-09-06
WO1993020848A1 (en) 1993-10-28
KR100291377B1 (de) 2001-09-17
CA2133838C (en) 2003-07-29
NZ252799A (en) 1996-10-28
NO314686B1 (no) 2003-05-05
CA2133838A1 (en) 1993-10-28
NO943776L (no) 1994-11-25
RU2127122C1 (ru) 1999-03-10
NO943776D0 (no) 1994-10-07
IL105344A (en) 2000-06-29
EP1656950A1 (de) 2006-05-17
EP0634938A4 (de) 1998-06-03
AU4280193A (en) 1993-11-18

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