EP0634938A4 - Gegen cd33 verwandte oberflächen-antigene gerichtete immuntoxine. - Google Patents
Gegen cd33 verwandte oberflächen-antigene gerichtete immuntoxine.Info
- Publication number
- EP0634938A4 EP0634938A4 EP93912143A EP93912143A EP0634938A4 EP 0634938 A4 EP0634938 A4 EP 0634938A4 EP 93912143 A EP93912143 A EP 93912143A EP 93912143 A EP93912143 A EP 93912143A EP 0634938 A4 EP0634938 A4 EP 0634938A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- directed against
- surface antigens
- related surface
- immunotoxins directed
- immunotoxins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04017939A EP1656950A1 (de) | 1992-04-10 | 1993-04-08 | Gegen CD33-bezogene Oberflächenantigene gerichtete immunotoxine |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86669392A | 1992-04-10 | 1992-04-10 | |
US866693 | 1992-04-10 | ||
PCT/US1993/003284 WO1993020848A1 (en) | 1992-04-10 | 1993-04-08 | Immunotoxins directed against cd33 related surface antigens |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP04017939A Division EP1656950A1 (de) | 1992-04-10 | 1993-04-08 | Gegen CD33-bezogene Oberflächenantigene gerichtete immunotoxine |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0634938A1 EP0634938A1 (de) | 1995-01-25 |
EP0634938A4 true EP0634938A4 (de) | 1998-06-03 |
Family
ID=25348185
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP93912143A Ceased EP0634938A4 (de) | 1992-04-10 | 1993-04-08 | Gegen cd33 verwandte oberflächen-antigene gerichtete immuntoxine. |
EP04017939A Withdrawn EP1656950A1 (de) | 1992-04-10 | 1993-04-08 | Gegen CD33-bezogene Oberflächenantigene gerichtete immunotoxine |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP04017939A Withdrawn EP1656950A1 (de) | 1992-04-10 | 1993-04-08 | Gegen CD33-bezogene Oberflächenantigene gerichtete immunotoxine |
Country Status (13)
Country | Link |
---|---|
EP (2) | EP0634938A4 (de) |
JP (1) | JP3949158B2 (de) |
KR (1) | KR950700760A (de) |
CN (1) | CN1056084C (de) |
AU (1) | AU675226B2 (de) |
CA (1) | CA2133838C (de) |
FI (1) | FI944730A (de) |
IL (1) | IL105344A (de) |
NO (1) | NO314686B1 (de) |
NZ (1) | NZ252799A (de) |
RU (1) | RU2127122C1 (de) |
WO (1) | WO1993020848A1 (de) |
ZA (1) | ZA932523B (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6599505B1 (en) | 1992-04-10 | 2003-07-29 | Research Development Foundation | Immunotoxins directed against CD33 related surface antigens |
IL112372A (en) * | 1994-02-07 | 2001-08-26 | Res Dev Foundation | Non-viral vector for the delivery of genetic information to cells |
AUPN115095A0 (en) * | 1995-02-15 | 1995-03-09 | Butt, Henry Lawrence | Analysis of and compositions and methods for the treatment of disease |
KR101021124B1 (ko) * | 2001-05-24 | 2011-03-14 | 지모제넥틱스, 인코포레이티드 | Taci-면역글로불린 융합 단백질 |
TW200726776A (en) * | 2005-07-29 | 2007-07-16 | Friedrich Alexander University Of Erlangen Nuremberg | CD33-specific single-chain immunotoxin and methods of use |
DE102009045006A1 (de) | 2009-09-25 | 2011-04-14 | Technische Universität Dresden | Anti-CD33 Antikörper und ihre Anwendung zum Immunotargeting bei der Behandlung von CD33-assoziierten Erkrankungen |
UA112062C2 (uk) | 2010-10-04 | 2016-07-25 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | Cd33-зв'язувальний агент |
EP2777714A1 (de) | 2013-03-15 | 2014-09-17 | NBE-Therapeutics LLC | Verfahren zur Herstellung eines Immunoliganden/Nutzlastkonjugats durch ein Sequenz-spezifisches Transpeptidase Enzym |
JP7497953B2 (ja) | 2015-06-12 | 2024-06-11 | アレクトル エルエルシー | 抗cd33抗体及びその使用方法 |
CN116063499A (zh) * | 2015-06-12 | 2023-05-05 | 艾利妥 | 抗cd33抗体及其使用方法 |
WO2019028283A1 (en) | 2017-08-03 | 2019-02-07 | Alector Llc | ANTI-CD33 ANTIBODIES AND METHODS OF USE |
CN113801229A (zh) | 2018-08-31 | 2021-12-17 | 艾利妥 | 抗cd33抗体及其使用方法 |
WO2023081898A1 (en) | 2021-11-08 | 2023-05-11 | Alector Llc | Soluble cd33 as a biomarker for anti-cd33 efficacy |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0350230A2 (de) * | 1988-07-07 | 1990-01-10 | RESEARCH DEVELOPMENT FOUNDATION (a Nevada corporation) | Immunokonjugate für Krebsdiagnostik und -therapie |
WO1991009058A1 (en) * | 1989-12-14 | 1991-06-27 | Sloan-Kettering Institute For Cancer Research | Therapeutic uses of the hypervariable region of monoclonal antibody m195 and constructs thereof |
-
1993
- 1993-01-01 ZA ZA932523A patent/ZA932523B/xx unknown
- 1993-04-08 IL IL10534493A patent/IL105344A/xx not_active IP Right Cessation
- 1993-04-08 AU AU42801/93A patent/AU675226B2/en not_active Ceased
- 1993-04-08 EP EP93912143A patent/EP0634938A4/de not_active Ceased
- 1993-04-08 NZ NZ252799A patent/NZ252799A/en not_active IP Right Cessation
- 1993-04-08 CA CA002133838A patent/CA2133838C/en not_active Expired - Fee Related
- 1993-04-08 WO PCT/US1993/003284 patent/WO1993020848A1/en not_active Application Discontinuation
- 1993-04-08 JP JP51845793A patent/JP3949158B2/ja not_active Expired - Fee Related
- 1993-04-08 EP EP04017939A patent/EP1656950A1/de not_active Withdrawn
- 1993-04-08 RU RU94045984A patent/RU2127122C1/ru not_active IP Right Cessation
- 1993-04-09 CN CN93104200A patent/CN1056084C/zh not_active Expired - Fee Related
-
1994
- 1994-10-07 FI FI944730A patent/FI944730A/fi not_active Application Discontinuation
- 1994-10-07 NO NO19943776A patent/NO314686B1/no unknown
- 1994-10-07 KR KR1019940703547A patent/KR950700760A/ko not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0350230A2 (de) * | 1988-07-07 | 1990-01-10 | RESEARCH DEVELOPMENT FOUNDATION (a Nevada corporation) | Immunokonjugate für Krebsdiagnostik und -therapie |
WO1991009058A1 (en) * | 1989-12-14 | 1991-06-27 | Sloan-Kettering Institute For Cancer Research | Therapeutic uses of the hypervariable region of monoclonal antibody m195 and constructs thereof |
Non-Patent Citations (4)
Title |
---|
MAN SUNG CO: "CHIMERIC AND HUMANIZED ANTIBODIES WITH SPECIFICITY FOR THE CD33 ANTIGEN1", JOURNAL OF IMMUNOLOGY, vol. 148, no. 4, 15 February 1992 (1992-02-15), pages 1149 - 1154, XP000368716 * |
SCHEINBERG D A ET AL: "A PHASE I TRIAL OF MONOCLONAL ANTIBODY M195 IN ACUTE MYELOGENOUS LEUKEMIA: SPECIFIC BONE MARROW TERGETING AND INTERNALIZATION OF RADIONUCLIDE", JOURNAL OF CLINICAL ONCOLOGY, vol. 9, no. 3, 1 March 1991 (1991-03-01), pages 478 - 490, XP000564602 * |
SCHEINBERG ET AL.: "Humanized and Mouse Anti-CD33-Gelonin Immunotoxins for Myeloid Leukemias", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, vol. 33, March 1992 (1992-03-01), pages 346, XP002061680 * |
See also references of WO9320848A1 * |
Also Published As
Publication number | Publication date |
---|---|
JPH08501059A (ja) | 1996-02-06 |
FI944730A0 (fi) | 1994-10-07 |
JP3949158B2 (ja) | 2007-07-25 |
KR950700760A (ko) | 1995-02-20 |
EP0634938A1 (de) | 1995-01-25 |
FI944730A (fi) | 1994-10-07 |
AU675226B2 (en) | 1997-01-30 |
CN1078401A (zh) | 1993-11-17 |
IL105344A0 (en) | 1993-08-18 |
CN1056084C (zh) | 2000-09-06 |
WO1993020848A1 (en) | 1993-10-28 |
KR100291377B1 (de) | 2001-09-17 |
CA2133838C (en) | 2003-07-29 |
NZ252799A (en) | 1996-10-28 |
NO314686B1 (no) | 2003-05-05 |
CA2133838A1 (en) | 1993-10-28 |
ZA932523B (en) | 1994-10-08 |
NO943776L (no) | 1994-11-25 |
RU2127122C1 (ru) | 1999-03-10 |
NO943776D0 (no) | 1994-10-07 |
IL105344A (en) | 2000-06-29 |
EP1656950A1 (de) | 2006-05-17 |
AU4280193A (en) | 1993-11-18 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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17P | Request for examination filed |
Effective date: 19941010 |
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AK | Designated contracting states |
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