ZA932327B - Novel derivatives of 2,3-dihydro-2,2,4,6,7-pentaalkyl-5-benzofuranols - Google Patents
Novel derivatives of 2,3-dihydro-2,2,4,6,7-pentaalkyl-5-benzofuranolsInfo
- Publication number
- ZA932327B ZA932327B ZA932327A ZA932327A ZA932327B ZA 932327 B ZA932327 B ZA 932327B ZA 932327 A ZA932327 A ZA 932327A ZA 932327 A ZA932327 A ZA 932327A ZA 932327 B ZA932327 B ZA 932327B
- Authority
- ZA
- South Africa
- Prior art keywords
- dihydro
- benzofuranols
- pentaalkyl
- novel derivatives
- free radical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP92400956 | 1992-04-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA932327B true ZA932327B (en) | 1993-10-18 |
Family
ID=8211646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA932327A ZA932327B (en) | 1992-04-06 | 1993-03-31 | Novel derivatives of 2,3-dihydro-2,2,4,6,7-pentaalkyl-5-benzofuranols |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0635009B1 (OSRAM) |
| JP (1) | JP3246741B2 (OSRAM) |
| KR (1) | KR950700895A (OSRAM) |
| AT (1) | ATE158287T1 (OSRAM) |
| AU (1) | AU670433B2 (OSRAM) |
| CA (1) | CA2132829C (OSRAM) |
| DE (1) | DE69314022T2 (OSRAM) |
| DK (1) | DK0635009T3 (OSRAM) |
| ES (1) | ES2110602T3 (OSRAM) |
| FI (1) | FI944655L (OSRAM) |
| GR (1) | GR3025577T3 (OSRAM) |
| HU (1) | HUT68926A (OSRAM) |
| IL (1) | IL105318A (OSRAM) |
| MX (1) | MX9301950A (OSRAM) |
| NO (1) | NO943726L (OSRAM) |
| NZ (1) | NZ251134A (OSRAM) |
| TW (1) | TW226371B (OSRAM) |
| WO (1) | WO1993020057A1 (OSRAM) |
| ZA (1) | ZA932327B (OSRAM) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5510373A (en) * | 1992-04-06 | 1996-04-23 | Merrell Pharmaceuticals Inc. | Cardioprotective agents |
| US5545660A (en) * | 1992-04-07 | 1996-08-13 | Merrell Pharmaceuticals Inc. | Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans |
| TW393475B (en) * | 1992-10-16 | 2000-06-11 | Chugai Pharmaceutical Co Ltd | 4-alkoxyl-2,6-di-t-butyl phenol derivatives |
| IT1256264B (it) * | 1992-12-31 | 1995-11-29 | Lifegroup Spa | N-acilderivati di idrossiammine dotati di attivita' scavenger ed utilizzabili nelle patologie acute e croniche correlate a fenomeni di perossidazione ed infiammazione |
| FI973644A7 (fi) * | 1995-03-10 | 1997-09-09 | Hoechst Marion Roussel Inc Inc | Uusi menetelmä 2,3-dihydrobentsofuranolijohdannaisten valmistamiseksi |
| US6140309A (en) * | 1996-03-12 | 2000-10-31 | University Of South Florida | Vasoactive effects and free radical generation by β-amyloid peptides |
| UA79834C2 (en) * | 2002-11-01 | 2007-07-25 | Viropharma Inc | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases |
| JP4369924B2 (ja) * | 2003-04-14 | 2009-11-25 | 日本曹達株式会社 | ジアミン誘導体、製造法及び抗酸化薬 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8704572D0 (en) * | 1987-02-26 | 1987-04-01 | Lundbeck & Co As H | Organic compounds |
| JP2855340B2 (ja) * | 1988-06-10 | 1999-02-10 | 武田薬品工業株式会社 | ２―置換クマラン誘導体 |
| IT1229482B (it) * | 1988-08-01 | 1991-09-03 | Foscama Biomed Chim Farma | Acidi (rs) 2 (2,3 diidro 5 idrossi 4,6,7 trimetilbenzofuranil) acetico e 2 (2,3 diidro 5 acilossi 4,6,7 trimetilbenzofuranil) acetici e loro esteri, utili come farmaci mucoregolatori ed antiischemici. |
| IT1231341B (it) * | 1989-08-18 | 1991-11-28 | Foscama Biomed Chim Farma | 2,3 diidro 5 ossi 4,6,7 trimetilbenzofurani 2 (rs) sostituiti, utili come farmaci antiossidanti con proprieta' mucoregolatrici e antiischemiche. |
| US4975457A (en) * | 1989-09-25 | 1990-12-04 | Merck & Co., Inc. | Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis |
| IE68675B1 (en) * | 1990-11-01 | 1996-07-10 | Takeda Chemical Industries Ltd | Aminocoumaran derivatives their production and use |
-
1993
- 1993-03-10 NZ NZ251134A patent/NZ251134A/en unknown
- 1993-03-10 ES ES93907336T patent/ES2110602T3/es not_active Expired - Lifetime
- 1993-03-10 HU HU9402864A patent/HUT68926A/hu unknown
- 1993-03-10 WO PCT/US1993/002107 patent/WO1993020057A1/en not_active Ceased
- 1993-03-10 DE DE69314022T patent/DE69314022T2/de not_active Expired - Fee Related
- 1993-03-10 CA CA002132829A patent/CA2132829C/en not_active Expired - Fee Related
- 1993-03-10 AT AT93907336T patent/ATE158287T1/de not_active IP Right Cessation
- 1993-03-10 FI FI944655A patent/FI944655L/fi unknown
- 1993-03-10 EP EP93907336A patent/EP0635009B1/en not_active Expired - Lifetime
- 1993-03-10 AU AU37976/93A patent/AU670433B2/en not_active Ceased
- 1993-03-10 DK DK93907336.7T patent/DK0635009T3/da active
- 1993-03-10 JP JP51745293A patent/JP3246741B2/ja not_active Expired - Fee Related
- 1993-03-31 ZA ZA932327A patent/ZA932327B/xx unknown
- 1993-04-01 TW TW082102444A patent/TW226371B/zh active
- 1993-04-05 MX MX9301950A patent/MX9301950A/es unknown
- 1993-04-05 IL IL105318A patent/IL105318A/en not_active IP Right Cessation
-
1994
- 1994-10-05 KR KR1019940703513A patent/KR950700895A/ko not_active Withdrawn
- 1994-10-05 NO NO943726A patent/NO943726L/no unknown
-
1997
- 1997-12-03 GR GR970403227T patent/GR3025577T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE158287T1 (de) | 1997-10-15 |
| IL105318A (en) | 1998-04-05 |
| EP0635009B1 (en) | 1997-09-17 |
| CA2132829C (en) | 1999-01-26 |
| NO943726L (no) | 1994-12-06 |
| ES2110602T3 (es) | 1998-02-16 |
| KR950700895A (ko) | 1995-02-20 |
| NO943726D0 (no) | 1994-10-05 |
| FI944655A0 (fi) | 1994-10-05 |
| DK0635009T3 (da) | 1997-10-06 |
| FI944655A7 (fi) | 1994-10-05 |
| GR3025577T3 (en) | 1998-03-31 |
| JPH08503922A (ja) | 1996-04-30 |
| IL105318A0 (en) | 1993-08-18 |
| DE69314022T2 (de) | 1998-02-12 |
| HUT68926A (en) | 1995-08-28 |
| NZ251134A (en) | 1997-06-24 |
| AU670433B2 (en) | 1996-07-18 |
| JP3246741B2 (ja) | 2002-01-15 |
| CA2132829A1 (en) | 1993-10-14 |
| FI944655L (fi) | 1994-10-05 |
| WO1993020057A1 (en) | 1993-10-14 |
| AU3797693A (en) | 1993-11-08 |
| EP0635009A1 (en) | 1995-01-25 |
| TW226371B (OSRAM) | 1994-07-11 |
| MX9301950A (es) | 1993-10-01 |
| DE69314022D1 (de) | 1997-10-23 |
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