ZA927164B - Production of crystalline penem - Google Patents

Production of crystalline penem

Info

Publication number
ZA927164B
ZA927164B ZA927164A ZA927164A ZA927164B ZA 927164 B ZA927164 B ZA 927164B ZA 927164 A ZA927164 A ZA 927164A ZA 927164 A ZA927164 A ZA 927164A ZA 927164 B ZA927164 B ZA 927164B
Authority
ZA
South Africa
Prior art keywords
production
penem
crystalline
crystalline penem
Prior art date
Application number
ZA927164A
Other languages
English (en)
Inventor
Masayoshi Kaneko
Shigeo Yabuno
Original Assignee
Takeda Chemical Industries Ltd
Lederle Japan Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd, Lederle Japan Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ZA927164B publication Critical patent/ZA927164B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA927164A 1991-09-20 1992-09-18 Production of crystalline penem ZA927164B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24164891 1991-09-20

Publications (1)

Publication Number Publication Date
ZA927164B true ZA927164B (en) 1994-03-18

Family

ID=17077445

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA927164A ZA927164B (en) 1991-09-20 1992-09-18 Production of crystalline penem

Country Status (9)

Country Link
US (2) US5286856A (fr)
EP (1) EP0533149A1 (fr)
JP (1) JP2767171B2 (fr)
KR (1) KR930006022A (fr)
FI (1) FI924210A (fr)
IL (1) IL103218A0 (fr)
NO (2) NO923619L (fr)
TW (1) TW264475B (fr)
ZA (1) ZA927164B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW264475B (fr) * 1991-09-20 1995-12-01 Takeda Pharm Industry Co Ltd
WO1995029913A1 (fr) * 1994-05-02 1995-11-09 Shionogi & Co., Ltd. Cristal de derive de pyrrolidylthiocarbapeneme, preparation lyophilisee le contenant et son procede de production
ATE321762T1 (de) * 1998-03-02 2006-04-15 Merck & Co Inc Verfahren zur synthese von carbapenem-antibiotika
DE10300620B4 (de) * 2002-05-18 2017-04-13 Carl Zeiss Meditec Ag Trägervorrichtung für ein medizinisch-optisches Gerät
KR101013535B1 (ko) * 2004-10-21 2011-02-14 주식회사 만도 자동차의 파워 스티어링 장치용 실린더 튜브와 피드튜브의 조립 구조물
PL2559689T3 (pl) 2006-09-25 2018-04-30 Ptc Therapeutics, Inc. Sposób wytwarzania postaci krystalicznych kwasu 3-[5-(2-fluorofenylo)[1,2,4]oksadiazol-3-ilo]benzoesowego
WO2009047604A1 (fr) * 2007-10-08 2009-04-16 Orchid Chemicals & Pharmaceuticals Limited Procédé de préparation de l'antibiotique carbapénème
DE102008043318A1 (de) 2008-10-30 2010-05-12 Mvg Metallverarbeitungsgesellschaft Mbh Anhängekupplung
WO2013132422A1 (fr) * 2012-03-05 2013-09-12 Orchid Chemicals & Pharmaceuticals Ltd Procédé amélioré pour la préparation d'un antibiotique carbapenem
SI2857401T1 (sl) 2012-05-30 2020-01-31 Meiji Seika Pharma Co., Ltd. Novi inhibitor beta-laktamaze in metoda za proizvajanje le-tega
WO2014097221A1 (fr) 2012-12-21 2014-06-26 Ranbaxy Laboratories Limited Procédé pour la purification de biapenem
AR097744A1 (es) 2013-09-24 2016-04-13 Meiji Seika Pharma Co Ltd Proceso para producir derivado de diazabiciclooctano y su intermediario
NZ719568A (en) 2013-10-08 2018-06-29 Meiji Seika Pharma Co Ltd Crystals of diazabicyclooctane derivative and production method for crystals of diazabicyclooctane derivative
ES2821826T3 (es) 2014-12-05 2021-04-27 Meiji Seika Pharma Co Ltd Método para producir cristales de derivado de diazabiciclooctano y preparación liofilizada estable
CN114349772B (zh) * 2020-10-13 2022-11-25 珠海联邦制药股份有限公司 一种比阿培南粗品的精制方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029655A (en) * 1975-04-11 1977-06-14 Eli Lilly And Company Method of preparing stable sterile crystalline cephalosporins for parenteral administration
IL53427A0 (en) * 1976-11-24 1978-01-31 Lilly Co Eli Method of preparing a rapidly dissolving powder of sterile crystalline cefozolin sodium for parenteral administration
JPS6024080B2 (ja) * 1977-06-01 1985-06-11 武田薬品工業株式会社 結晶の製造法
GB1589317A (en) * 1977-11-24 1981-05-13 Lilly Co Eli Freeze drying cephalothin sodium
JPS56120615A (en) * 1980-02-27 1981-09-22 Nippon Chemiphar Co Ltd Preparation of lyophilized powder of cephalothin
US4713451A (en) * 1984-04-09 1987-12-15 Merck & Co., Inc. Crystalline dimethyliminothienamycin
IE60588B1 (en) * 1986-07-30 1994-07-27 Sumitomo Pharma Carbapenem compound in crystalline form, and its production and use
US4866171A (en) * 1987-04-11 1989-09-12 Lederle (Japan), Ltd. (1R,5S,6S)-2-[(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazolium-6-yl)]thio-6-[R-1-hydroxyethyl]-1-methyl-carbapenum-3-carboxylate
JPS6425779A (en) * 1987-04-11 1989-01-27 Lederle Japan Ltd (1r,5s,6s)-2-substituted-thio-6-((r)-1-hydroxyethyl)-1-methyl -carbapenem-3-carboxylic acid derivative
DK168047B1 (da) * 1987-12-07 1994-01-24 Lederle Japan Ltd (1r,5s,6s)-2-substitueret thio-6-oe(r)-1-hydroxyethylaa-1-methyl-carbapenem-3-carboxylsyrederivater, fremgangsmaade til remstilling deraf, midler og praeparater indeholdende den krystallinske forbindelse samt dens anvendelse.
US5082661A (en) * 1990-09-26 1992-01-21 Elizabeth Arden Co., Division Of Conopco, Inc. Odorless cosmetic compositions in gelatin capsules
GB9021061D0 (en) * 1990-09-27 1990-11-07 Unilever Plc Encapsulating method and products containing encapsulated material
TW264475B (fr) * 1991-09-20 1995-12-01 Takeda Pharm Industry Co Ltd
RU2127275C1 (ru) * 1993-01-29 1999-03-10 Агурон Фармасьютикалз, Инк. 2-[4-[2-(2-амино-4-оксо-4,6,7,8-тетрагидро-3h-пиримидо[5,4-b] [1,4]тиазин-6- ил)этил] бензоил(или тиенилкарбонил)амино]пентандиовая кислота или ее низший алкиловый эфир, способ ингибирования роста и пролиферации клеток и способ ингибирования фермента

Also Published As

Publication number Publication date
TW264475B (fr) 1995-12-01
NO923619L (no) 1993-03-22
US5286856A (en) 1994-02-15
FI924210A (fi) 1993-03-21
IL103218A0 (en) 1993-02-21
JPH05271241A (ja) 1993-10-19
NO923619D0 (no) 1992-09-17
JP2767171B2 (ja) 1998-06-18
AU2459792A (en) 1993-03-25
KR930006022A (ko) 1993-04-20
US5424069A (en) 1995-06-13
EP0533149A1 (fr) 1993-03-24
NO971332L (no) 1993-03-22
FI924210A0 (fi) 1992-09-18
AU645442B2 (en) 1994-01-13
NO971332D0 (no) 1997-03-21

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