ZA926434B - N-substituted aminomethanediphosphonic acids - Google Patents

N-substituted aminomethanediphosphonic acids

Info

Publication number
ZA926434B
ZA926434B ZA926434A ZA926434A ZA926434B ZA 926434 B ZA926434 B ZA 926434B ZA 926434 A ZA926434 A ZA 926434A ZA 926434 A ZA926434 A ZA 926434A ZA 926434 B ZA926434 B ZA 926434B
Authority
ZA
South Africa
Prior art keywords
acids
substituted
substituted aminomethanediphosphonic
aminomethanediphosphonic acids
alk1
Prior art date
Application number
ZA926434A
Other languages
English (en)
Inventor
Knut Alfred Jaeggi
Alfred Jaeggi Knut
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of ZA926434B publication Critical patent/ZA926434B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Dental Preparations (AREA)
ZA926434A 1991-08-27 1992-08-26 N-substituted aminomethanediphosphonic acids ZA926434B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91810682 1991-08-27

Publications (1)

Publication Number Publication Date
ZA926434B true ZA926434B (en) 1993-04-28

Family

ID=8208873

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA926434A ZA926434B (en) 1991-08-27 1992-08-26 N-substituted aminomethanediphosphonic acids

Country Status (19)

Country Link
US (1) US5281748A (fr)
EP (1) EP0531253B1 (fr)
JP (1) JPH05222074A (fr)
KR (1) KR930004317A (fr)
AT (1) ATE147396T1 (fr)
AU (1) AU657983B2 (fr)
CA (1) CA2076801A1 (fr)
DE (1) DE69216514T2 (fr)
DK (1) DK0531253T3 (fr)
ES (1) ES2096061T3 (fr)
FI (1) FI923797A (fr)
GR (1) GR3022243T3 (fr)
HU (1) HUT62303A (fr)
IL (1) IL102959A (fr)
MX (1) MX9204905A (fr)
NO (1) NO923331L (fr)
NZ (1) NZ244078A (fr)
TW (1) TW207543B (fr)
ZA (1) ZA926434B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0541037A3 (en) * 1991-11-06 1997-02-26 Takeda Chemical Industries Ltd Squalene synthetase inhibitory composition and use thereof
TW258729B (fr) * 1992-06-22 1995-10-01 Ciba Geigy
DE4223940A1 (de) * 1992-07-21 1994-01-27 Boehringer Mannheim Gmbh Neue acyclische Amidingruppen-haltige Diphosphonsäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
GB9300641D0 (en) * 1993-01-14 1993-03-03 Zeneca Ltd Process
DE19719680A1 (de) * 1997-05-09 1998-11-19 Boehringer Mannheim Gmbh Verwendung von Diphosphonsäuren zur präventiven Behandlung von Spätfolgen bei Harnblasenerweiterung oder Harnblasenersatz
IT1303672B1 (it) 1998-07-28 2001-02-23 Nicox Sa Sali nitrati di farmaci attivi nei disordini ossei

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2316396C3 (de) * 1973-04-02 1975-09-18 Joh. A. Benckiser Gmbh, 6700 Ludwigshafen N(1,1-Di-phosphono-äthyl)acetamidin, seine Herste lung und Verwendung zur Steinverhütung
DE3208600A1 (de) * 1982-03-10 1983-09-22 Henkel KGaA, 4000 Düsseldorf Amidinodiphosphonsaeuren
US4761406A (en) * 1985-06-06 1988-08-02 The Procter & Gamble Company Regimen for treating osteoporosis
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US4963681A (en) * 1987-07-06 1990-10-16 Norwich Eaton Pharmaceuticals, Inc. Process for synthesis of aminomethylene phosphonoalkylphosphinates
PH26923A (en) * 1989-03-08 1992-12-03 Ciba Geigy N-substituted amino alkanediphosphonic acids
IE912115A1 (en) * 1990-06-25 1992-01-01 Takeda Chemical Industries Ltd Bisphosphonic acid derivatives, their production and use
US5043099A (en) * 1990-07-13 1991-08-27 Kreh Robert P Mono- and di-substituted (diphosphonoalkylamino methyl)-4-hydroxybenzenesulfonic acid
CA2058012A1 (fr) * 1990-12-19 1992-06-20 Takashi Sohda Derives de l'acide bisphophonique; preparation et utilisation

Also Published As

Publication number Publication date
NO923331L (no) 1993-03-01
DK0531253T3 (da) 1997-01-27
ATE147396T1 (de) 1997-01-15
IL102959A0 (en) 1993-01-31
DE69216514D1 (de) 1997-02-20
TW207543B (fr) 1993-06-11
EP0531253A1 (fr) 1993-03-10
CA2076801A1 (fr) 1993-02-28
IL102959A (en) 1998-01-04
JPH05222074A (ja) 1993-08-31
NZ244078A (en) 1994-12-22
AU2128892A (en) 1993-03-04
NO923331D0 (no) 1992-08-26
FI923797A0 (fi) 1992-08-24
DE69216514T2 (de) 1997-07-31
AU657983B2 (en) 1995-03-30
US5281748A (en) 1994-01-25
KR930004317A (ko) 1993-03-22
ES2096061T3 (es) 1997-03-01
HU9202754D0 (en) 1992-12-28
MX9204905A (es) 1993-04-01
FI923797A (fi) 1993-02-28
EP0531253B1 (fr) 1997-01-08
GR3022243T3 (en) 1997-04-30
HUT62303A (en) 1993-04-28

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