ZA925324B - Decahydro-8h-isoquino Ú2,1-g¾ Ú1,6¾naphthyridine and decahydrobenzo Úa¾pyrrolo Ú2,3-e¾quinolizine derivatives - Google Patents

Decahydro-8h-isoquino Ú2,1-g¾ Ú1,6¾naphthyridine and decahydrobenzo Úa¾pyrrolo Ú2,3-e¾quinolizine derivatives

Info

Publication number
ZA925324B
ZA925324B ZA925324A ZA925324A ZA925324B ZA 925324 B ZA925324 B ZA 925324B ZA 925324 A ZA925324 A ZA 925324A ZA 925324 A ZA925324 A ZA 925324A ZA 925324 B ZA925324 B ZA 925324B
Authority
ZA
South Africa
Prior art keywords
decahydrobenzo
isoquino
decahydro
derivatives
Prior art date
Application number
ZA925324A
Other languages
English (en)
Inventor
Robin D Clark
Michael Spedding
William Salisbury Redfern
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of ZA925324B publication Critical patent/ZA925324B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA925324A 1991-07-17 1992-07-16 Decahydro-8h-isoquino Ú2,1-g¾ Ú1,6¾naphthyridine and decahydrobenzo Úa¾pyrrolo Ú2,3-e¾quinolizine derivatives ZA925324B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73169191A 1991-07-17 1991-07-17

Publications (1)

Publication Number Publication Date
ZA925324B true ZA925324B (en) 1994-07-17

Family

ID=24940584

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA925324A ZA925324B (en) 1991-07-17 1992-07-16 Decahydro-8h-isoquino Ú2,1-g¾ Ú1,6¾naphthyridine and decahydrobenzo Úa¾pyrrolo Ú2,3-e¾quinolizine derivatives

Country Status (14)

Country Link
EP (1) EP0524004A1 (he)
JP (1) JPH0665242A (he)
KR (1) KR930002346A (he)
AU (1) AU655998B2 (he)
CA (1) CA2074038A1 (he)
FI (1) FI923267A (he)
HU (2) HUT61550A (he)
IE (1) IE922314A1 (he)
IL (1) IL102521A (he)
IT (1) IT1256880B (he)
NO (1) NO922812L (he)
NZ (1) NZ243586A (he)
TW (1) TW209219B (he)
ZA (1) ZA925324B (he)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2327740T3 (es) 2003-06-20 2009-11-03 F. Hoffmann-La Roche Ag Hexahidropiridoisoquinolinas como inhibidoras de la dpp-iv.
CN103387583B (zh) * 2012-05-09 2018-04-13 中国科学院上海药物研究所 二芳基并[a,g]喹嗪类化合物、其制备方法、药物组合物及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791108A (en) * 1987-04-13 1988-12-13 Syntex (U.S.A.) Inc. Sulfonyl-decahydro-8H-isoquino[2,1-G][1,6]-naphthyridines and related compounds useful as α2 -blockers

Also Published As

Publication number Publication date
AU2031392A (en) 1993-01-21
FI923267A (fi) 1993-01-18
TW209219B (he) 1993-07-11
JPH0665242A (ja) 1994-03-08
IE922314A1 (en) 1993-01-27
NO922812L (no) 1993-01-18
HU210711A9 (en) 1995-06-28
NO922812D0 (no) 1992-07-16
HU9202333D0 (en) 1992-10-28
IT1256880B (it) 1995-12-27
ITTO920606A0 (it) 1992-07-16
AU655998B2 (en) 1995-01-19
IL102521A (he) 1996-05-14
ITTO920606A1 (it) 1994-01-16
NZ243586A (en) 1995-03-28
HUT61550A (en) 1993-01-28
FI923267A0 (fi) 1992-07-16
KR930002346A (ko) 1993-02-23
EP0524004A1 (en) 1993-01-20
CA2074038A1 (en) 1993-01-18

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