ZA925093B - 6-oxo-azepinoindol compounds as well as a process and intermediate products for the production thereof,and drugs that contain these compounds - Google Patents

6-oxo-azepinoindol compounds as well as a process and intermediate products for the production thereof,and drugs that contain these compounds

Info

Publication number
ZA925093B
ZA925093B ZA925093A ZA925093A ZA925093B ZA 925093 B ZA925093 B ZA 925093B ZA 925093 A ZA925093 A ZA 925093A ZA 925093 A ZA925093 A ZA 925093A ZA 925093 B ZA925093 B ZA 925093B
Authority
ZA
South Africa
Prior art keywords
lower alkyl
compounds
cycloalkyl
alkyl group
optionally substituted
Prior art date
Application number
ZA925093A
Other languages
English (en)
Inventor
Werner Benson
Benson Werner
Karin Van Charldorp
Van Charldorp Karin
Peter Colin Gregory
Colin Gregory Peter
Klaus-Ullrich Wolf
Wolf Klaus-Ullrich
Ulf Preuschoff
Preuschoff Ulf
Martin Tulp
Tulp Martin
Ton Hulkenberg
Hulkenberg Ton
Ineke Van Wijngaarden
Van Wijngaarden Ineke
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of ZA925093B publication Critical patent/ZA925093B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
ZA925093A 1991-07-31 1992-07-08 6-oxo-azepinoindol compounds as well as a process and intermediate products for the production thereof,and drugs that contain these compounds ZA925093B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4125292A DE4125292A1 (de) 1991-07-31 1991-07-31 6-oxo-azepinoindol-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ZA925093B true ZA925093B (en) 1993-04-28

Family

ID=6437366

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA925093A ZA925093B (en) 1991-07-31 1992-07-08 6-oxo-azepinoindol compounds as well as a process and intermediate products for the production thereof,and drugs that contain these compounds

Country Status (21)

Country Link
US (1) US5272143A (fr)
EP (1) EP0525584B1 (fr)
JP (1) JP3174158B2 (fr)
KR (1) KR930002353A (fr)
CN (2) CN1069733A (fr)
AT (1) ATE161012T1 (fr)
AU (1) AU649153B2 (fr)
CA (1) CA2075102A1 (fr)
CZ (1) CZ239392A3 (fr)
DE (2) DE4125292A1 (fr)
ES (1) ES2110454T3 (fr)
FI (1) FI923440A (fr)
HU (2) HU211105B (fr)
IE (1) IE922310A1 (fr)
IL (1) IL102503A (fr)
MX (1) MX9204457A (fr)
NO (1) NO300375B1 (fr)
NZ (1) NZ243715A (fr)
RU (1) RU2078765C1 (fr)
TW (1) TW207541B (fr)
ZA (1) ZA925093B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5414130A (en) * 1993-12-23 1995-05-09 The Dow Chemical Company Process for the preparation of diaminoresorcinol
JP4093448B2 (ja) * 1999-01-11 2008-06-04 アグロン・ファーマシューティカルズ・インコーポレーテッド ポリ（ａｄｐ−リボース）ポリメラーゼの三環系阻害剤
ECSP003637A (es) 1999-08-31 2002-03-25 Agouron Pharma Inhibidores triciclicos de poli (adp-ribosa) polimerasas
US8124600B2 (en) 2008-05-29 2012-02-28 Albany Molecular Research, Inc. 5-HT3 receptor modulators, methods of making, and use thereof
RS55487B1 (sr) * 2010-02-12 2017-04-28 Pfizer Soli i polimorfi 8-fluoro-2-{4-[(metilamino}metil]fenil}-1,3,4,5-tetrahidro-6h-azepino[5,4,3-cd]indol-6-ona
US10513515B2 (en) 2017-08-25 2019-12-24 Biotheryx, Inc. Ether compounds and uses thereof
CA3106239A1 (fr) 2018-07-27 2020-01-30 Biotheryx, Inc. Composes bifonctionnels agissant par agonisme sur des cdk
WO2021222150A2 (fr) 2020-04-28 2021-11-04 Anwita Biosciences, Inc. Polypeptides d'interleukine-2 et protéines de fusion de ceux-ci, ainsi que leurs compositions pharmaceutiques et leurs applications thérapeutiques

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4910193A (en) * 1985-12-16 1990-03-20 Sandoz Ltd. Treatment of gastrointestinal disorders

Also Published As

Publication number Publication date
TW207541B (fr) 1993-06-11
HU210217A9 (en) 1995-02-28
HU211105B (en) 1995-10-30
HUT65453A (en) 1994-06-28
AU649153B2 (en) 1994-05-12
EP0525584B1 (fr) 1997-12-10
EP0525584A1 (fr) 1993-02-03
KR930002353A (ko) 1993-02-23
IL102503A (en) 1995-12-31
NO300375B1 (no) 1997-05-20
NO923004L (no) 1993-02-01
IL102503A0 (en) 1993-01-14
JPH05202052A (ja) 1993-08-10
IE922310A1 (en) 1993-02-10
DE59209055D1 (de) 1998-01-22
HU9202430D0 (en) 1992-10-28
ES2110454T3 (es) 1998-02-16
CA2075102A1 (fr) 1993-02-01
US5272143A (en) 1993-12-21
FI923440A0 (fi) 1992-07-30
MX9204457A (es) 1993-05-01
ATE161012T1 (de) 1997-12-15
FI923440A (fi) 1993-02-01
AU2067792A (en) 1993-02-04
JP3174158B2 (ja) 2001-06-11
CN1141773A (zh) 1997-02-05
NO923004D0 (no) 1992-07-30
NZ243715A (en) 1995-03-28
RU2078765C1 (ru) 1997-05-10
CN1069733A (zh) 1993-03-10
DE4125292A1 (de) 1993-02-04
CZ239392A3 (en) 1993-04-14

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