ZA923980B - Hepatocyte Growth stimulation - Google Patents

Hepatocyte Growth stimulation

Info

Publication number
ZA923980B
ZA923980B ZA923980A ZA923980A ZA923980B ZA 923980 B ZA923980 B ZA 923980B ZA 923980 A ZA923980 A ZA 923980A ZA 923980 A ZA923980 A ZA 923980A ZA 923980 B ZA923980 B ZA 923980B
Authority
ZA
South Africa
Prior art keywords
hepatocyte growth
hgf
gamma
growth stimulation
ifn
Prior art date
Application number
ZA923980A
Other languages
English (en)
Inventor
Paula M Jardieu
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of ZA923980B publication Critical patent/ZA923980B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/217—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
ZA923980A 1991-06-10 1992-06-01 Hepatocyte Growth stimulation ZA923980B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/712,284 US5227158A (en) 1991-06-10 1991-06-10 Method of stimulating hepatocyte proliferation by administration of hepatocyte growth factor and gamma-interferon

Publications (1)

Publication Number Publication Date
ZA923980B true ZA923980B (en) 1993-12-01

Family

ID=24861484

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA923980A ZA923980B (en) 1991-06-10 1992-06-01 Hepatocyte Growth stimulation

Country Status (12)

Country Link
US (1) US5227158A (xx)
EP (1) EP0606210B1 (xx)
JP (1) JPH06508148A (xx)
AT (1) ATE151292T1 (xx)
AU (1) AU655653B2 (xx)
CA (1) CA2109434A1 (xx)
DE (1) DE69218956T2 (xx)
DK (1) DK0606210T3 (xx)
ES (1) ES2101849T3 (xx)
GR (1) GR3023613T3 (xx)
WO (1) WO1992022321A1 (xx)
ZA (1) ZA923980B (xx)

Families Citing this family (40)

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Publication number Priority date Publication date Assignee Title
US5362716A (en) * 1989-12-27 1994-11-08 The United States Of America As Represented By The Department Of Health And Human Services Methods for stimulating hematopoietic progenitors using hepatocyte growth factor and lymphokines
EP0642585B1 (en) * 1992-05-18 2005-12-28 Genentech, Inc. Activation of oligomerizing receptors by using fused receptor ligands
US5763584A (en) * 1992-05-18 1998-06-09 Genentech, Inc. Receptor activation with hepatocyte growth factor agonists
JPH08501314A (ja) * 1992-09-16 1996-02-13 ジェネンテク，インコーポレイテッド Ｈｇｆによる肝臓障害に対する保護
US5464815A (en) * 1993-09-08 1995-11-07 Genentech, Inc. Inhibition of heparin-binding
JP3680114B2 (ja) * 1993-09-17 2005-08-10 敏一 中村 脳神経障害治療剤
US5696086A (en) * 1994-11-03 1997-12-09 Genentech, Inc. Methods and kits using macrophage stimulating protein
US6214344B1 (en) 1995-06-02 2001-04-10 Genetech, Inc. Hepatocyte growth factor receptor antagonists and uses thereof
US5686292A (en) * 1995-06-02 1997-11-11 Genentech, Inc. Hepatocyte growth factor receptor antagonist antibodies and uses thereof
US5646036A (en) * 1995-06-02 1997-07-08 Genentech, Inc. Nucleic acids encoding hepatocyte growth factor receptor antagonist antibodies
US5855918A (en) * 1995-09-12 1999-01-05 Genentech, Inc. Cystic fibrosis therapy
WO1997012628A1 (en) * 1995-10-05 1997-04-10 Genentech, Inc. Methods and compositions for treating vascular stenosis
AU7254896A (en) * 1995-10-05 1997-04-28 Genentech Inc. Improved angiogenesis using hepatocyte growth factor
CN1055517C (zh) * 1996-03-29 2000-08-16 唐禾天 叶片转子式发动机
US6280739B1 (en) 1996-04-18 2001-08-28 Genetics Institute, Inc. Method of inhibiting angiogenesis using secreted proteins
DK0922102T3 (da) * 1996-07-03 2010-08-16 Genentech Inc Receptor-agonister af hepatocyt-vækstfaktor og anvendelser deraf
US20020136721A1 (en) * 1998-02-17 2002-09-26 Schwall Ralph H. Hepatocyte growth factor receptor antagonists and uses thereof
CN100536919C (zh) * 2001-01-09 2009-09-09 贝勒研究院 干扰素拮抗剂和Flt3L拮抗剂的用途
US20050123925A1 (en) 2002-11-15 2005-06-09 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
JP5111729B2 (ja) * 2002-06-05 2013-01-09 ジェネンテック， インコーポレイテッド 肝成長及び肝保護のための組成物と方法
TWI353991B (en) 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
EP1697415A1 (en) 2003-11-12 2006-09-06 Biogen Idec MA Inc. NEONATAL Fc RECEPTOR (FcRn)-BINDING POLYPEPTIDE VARIANTS, DIMERIC Fc BINDING PROTEINS AND METHODS RELATED THERETO
PL1718677T3 (pl) * 2003-12-19 2012-09-28 Genentech Inc Jednowartościowe fragmenty przeciwciała stosowane jako środki lecznicze
US20050244959A1 (en) * 2004-03-30 2005-11-03 Anne Corlu Methods for inducing active hepatocytes proliferation, kits using such methods and uses of said kits
DK1781698T3 (en) * 2004-07-20 2016-10-03 Genentech Inc COMPOSITIONS AND METHODS FOR THE USE OF Angiopoietin-like-4-PROTEIN
DK1773885T3 (da) * 2004-08-05 2010-08-16 Genentech Inc Humaniserede anti-c-met-antagonister
ES2408704T3 (es) 2005-01-05 2013-06-21 Biogen Idec Ma Inc. Moléculas de unión a Cripto
WO2006113767A2 (en) 2005-04-15 2006-10-26 Genentech, Inc. Hgf beta chain variants
US8236761B2 (en) * 2006-07-07 2012-08-07 Washington State University Research Foundation C-Met receptor regulation by angiotensin IV (AT4) receptor ligands
WO2008005531A2 (en) * 2006-07-07 2008-01-10 Washington State University Research Foundation C-met receptor regulation by angiotensin iv (at4) receptor ligands
AU2009221729A1 (en) * 2008-03-06 2009-09-11 Genentech, Inc. Combination therapy with c-met and HER antagonists
MX2013000301A (es) 2010-07-09 2013-05-09 Biogen Idec Hemophilia Inc Factores quimericos de coagulacion.
US20130004484A1 (en) 2011-06-30 2013-01-03 Genentech, Inc. Anti-c-met antibody formulations
US9738707B2 (en) 2011-07-15 2017-08-22 Biogen Ma Inc. Heterodimeric Fc regions, binding molecules comprising same, and methods relating thereto
HUE039033T2 (hu) 2012-01-10 2018-12-28 Biogen Ma Inc Terápiás molekulák transzportjának fokozása a vér-agy gáton keresztül
AU2014228938B2 (en) 2013-03-15 2019-05-02 Bioverativ Therapeutics Inc. Factor IX polypeptide formulations
RU2016141385A (ru) 2014-03-24 2018-04-28 Дженентек, Инк. Лечение рака антагонистами с-мет и их корреляция с экспрессией hgf
JP6772156B2 (ja) 2015-02-04 2020-10-21 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 治療用分子を選択する方法
MX2017010066A (es) 2015-02-04 2017-11-01 Hoffmann La Roche Oligomeros antisentido de tau y usos de los mismos.
RU2720451C1 (ru) * 2019-05-06 2020-04-29 Анастасия Юрьевна Лаптиёва Способ стимуляции пострезекционной пролиферации гепатоцитов путем внутрипеченочного введения цианокобаламина

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
JP2564486B2 (ja) * 1986-07-14 1996-12-18 修治 橋本 肝細胞増殖因子
EP0294160A1 (en) * 1987-06-02 1988-12-07 Schering Corporation Treatment of chronic type b hepatitis with a combination of recombinant human alpha and gamma interferons
US4973478A (en) * 1987-07-20 1990-11-27 Allelix Biopharmaceuticals, Inc. Treating inflammation with hepatocyte stimulating factor interferon β2
AU2855189A (en) * 1988-01-25 1989-07-27 Baker Cummins Dermatologicals, Inc. Method of treating fibrotic disorders

Also Published As

Publication number Publication date
CA2109434A1 (en) 1992-12-11
AU655653B2 (en) 1995-01-05
DK0606210T3 (da) 1997-05-05
ES2101849T3 (es) 1997-07-16
EP0606210B1 (en) 1997-04-09
AU2144192A (en) 1993-01-12
EP0606210A1 (en) 1994-07-20
DE69218956D1 (de) 1997-05-15
DE69218956T2 (de) 1997-07-31
ATE151292T1 (de) 1997-04-15
JPH06508148A (ja) 1994-09-14
WO1992022321A1 (en) 1992-12-23
GR3023613T3 (en) 1997-08-29
US5227158A (en) 1993-07-13

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