ZA923486B - Penetration enhancing substance - Google Patents

Penetration enhancing substance

Info

Publication number
ZA923486B
ZA923486B ZA923486A ZA923486A ZA923486B ZA 923486 B ZA923486 B ZA 923486B ZA 923486 A ZA923486 A ZA 923486A ZA 923486 A ZA923486 A ZA 923486A ZA 923486 B ZA923486 B ZA 923486B
Authority
ZA
South Africa
Prior art keywords
pct
penetration enhancing
date nov
substances
sec
Prior art date
Application number
ZA923486A
Other languages
English (en)
Inventor
Reinhard Von Dr Kleinsorgen
Von Kleinsorgen Dr Reinhard
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of ZA923486B publication Critical patent/ZA923486B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Steroid Compounds (AREA)
ZA923486A 1991-05-15 1992-05-14 Penetration enhancing substance ZA923486B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4115849A DE4115849A1 (de) 1991-05-15 1991-05-15 Penetrationsfoerdernde substanz

Publications (1)

Publication Number Publication Date
ZA923486B true ZA923486B (en) 1993-01-27

Family

ID=6431707

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA923486A ZA923486B (en) 1991-05-15 1992-05-14 Penetration enhancing substance

Country Status (24)

Country Link
US (1) US5492698A (da)
EP (1) EP0584126B1 (da)
JP (1) JP2547301B2 (da)
KR (1) KR100248365B1 (da)
AT (1) ATE151643T1 (da)
AU (1) AU658626B2 (da)
CA (1) CA2103060C (da)
CZ (1) CZ284034B6 (da)
DE (2) DE4115849A1 (da)
DK (1) DK0584126T3 (da)
ES (1) ES2103369T3 (da)
FI (1) FI107705B (da)
GR (1) GR3024015T3 (da)
HU (1) HU219225B (da)
IE (1) IE80626B1 (da)
IL (1) IL101710A (da)
MY (1) MY131090A (da)
NO (1) NO306762B1 (da)
NZ (1) NZ242722A (da)
PH (1) PH31463A (da)
SK (1) SK126093A3 (da)
WO (1) WO1992020378A1 (da)
YU (1) YU47192A (da)
ZA (1) ZA923486B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07300419A (ja) * 1993-12-06 1995-11-14 Lansinoh Lab Inc ラノリン／ラノリン酸エステル皮膚処置用組成物
ES2191834T3 (es) * 1996-10-24 2003-09-16 Alza Corp Agentes que facilitan la permeacion y destinados para composiciones, dispositivos y procedimientos de aporte transdermico de medicamentos.
US20060002959A1 (en) * 1996-11-14 2006-01-05 Government Of The United States Skin-sctive adjuvants for transcutaneous immuization
US5980898A (en) * 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US20060002949A1 (en) * 1996-11-14 2006-01-05 Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. Transcutaneous immunization without heterologous adjuvant
US20040258703A1 (en) * 1997-11-14 2004-12-23 The Government Of The Us, As Represented By The Secretary Of The Army Skin-active adjuvants for transcutaneous immunization
DE19834007C1 (de) * 1998-07-29 2000-02-24 Lohmann Therapie Syst Lts Estradiolhaltiges Pflaster zur transdermalen Applikation von Hormonen und seine Verwendung
AU4188100A (en) * 1999-04-08 2000-11-14 Gregory M. Glenn Dry formulation for transcutaneous immunization
ATE398461T1 (de) * 2001-02-13 2008-07-15 Us Gov Sec Army Impstoffe zur transkutanen immunisierung gegen reisediarrhö
EP1390383B1 (en) * 2001-05-11 2012-02-29 Isis Pharmaceuticals, Inc. Antisense permeation enhancers
EA007956B1 (ru) * 2003-11-05 2007-02-27 Алишир Вейс Оглу Мусаев Способ приготовления препарата на основе нафталановой нефти
US20060124246A1 (en) * 2004-12-14 2006-06-15 Pitney Bowes Incorporated Moistening fluids that destroy and/or inhibit the growth of biological organisms
WO2006079830A1 (en) * 2005-01-29 2006-08-03 Croda International Plc Alkoxylated lanolin derivatives and compositions therewith

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3527864A (en) * 1966-11-18 1970-09-08 Procter & Gamble Compositions for topical application to animal tissue and method of enhancing penetration thereof
US3472931A (en) * 1969-01-17 1969-10-14 Foster Milburn Co Percutaneous absorption with lower alkyl amides
LU62873A1 (da) * 1971-03-29 1972-12-07
FR2155777A1 (en) * 1971-10-04 1973-05-25 Innothera Lab Sa Mixt of lanolin deriv, lauryl alcohol derivs and polyethylene - glycol - for use as a cosmetic cleansing agent and pharmaceutical exc
US3891757A (en) * 1971-11-11 1975-06-24 Alza Corp Anaesthetic topical and percutaneous administration with selected promoters
US3903256A (en) * 1972-02-07 1975-09-02 Procter & Gamble Compositions for topical application of animal tissue and method of enhancing penetration thereof
US3896238A (en) * 1972-04-05 1975-07-22 Procter & Gamble Dermatological compositions
US3952099A (en) * 1973-03-13 1976-04-20 The Procter & Gamble Company Dermatological compositions
US4046886A (en) * 1975-01-17 1977-09-06 The Procter & Gamble Company Dermatological compositions
US4405616A (en) * 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
US4130667A (en) * 1976-01-12 1978-12-19 The Procter & Gamble Company Dermatological compositions
US4146649A (en) * 1976-10-14 1979-03-27 Faberge, Incorporated Skin moisturizing composition containing a polyethoxy fatty alcohol and a polyethoxy glycoside
US4335115A (en) * 1976-11-01 1982-06-15 The Procter & Gamble Company Anti-acne composition
AU520987B2 (en) * 1978-05-08 1982-03-11 Victor Alexander Garten Anti-arthritic preparation
US4299826A (en) * 1979-10-12 1981-11-10 The Procter & Gamble Company Anti-acne composition
US4379454A (en) * 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
US4343798A (en) * 1981-06-23 1982-08-10 The Procter & Gamble Company Topical antimicrobial anti-inflammatory compositions
SU1090400A1 (ru) * 1982-05-05 1984-05-07 Предприятие П/Я Г-4740 Крем дл кожи лица
GB8514090D0 (en) * 1985-06-04 1985-07-10 Sandoz Ltd Organic compounds
EP0147883A3 (en) * 1983-12-21 1986-12-30 Janssen Pharmaceutica N.V. Aqueous non-aggressive anthelmintic pour-on formulations
JPS6124517A (ja) * 1984-07-11 1986-02-03 Nichiban Co Ltd 循環器疾患用貼布治療製剤
EP0189861A3 (en) * 1985-01-26 1988-02-17 Showa Denko Kabushiki Kaisha Percutaneous absorption accelerator for ionic water-soluble medicine
US4690683A (en) * 1985-07-02 1987-09-01 Rutgers, The State University Of New Jersey Transdermal varapamil delivery device
EP0266968A3 (en) * 1986-11-03 1988-08-24 Gérard G. Cohen Gelled ointment of vasodilating agent
SU1532046A1 (ru) * 1987-08-05 1989-12-30 Научно-производственное объединение "Аэрозоль" Крем дл рук
US5057497A (en) * 1987-11-10 1991-10-15 Calam & Associates, Inc. Oral method for the maintenance of healthy gingival tissues using TRF
DE3807283A1 (de) * 1988-03-05 1989-09-14 Basf Ag Verfahren zur herstellung eines pflasters zur transdermalen anwendung pharmazeutischer wirkstoffe
ZA898331B (en) * 1988-11-22 1990-07-25 Hoffmann La Roche Pharmaceutical compositions

Also Published As

Publication number Publication date
SK126093A3 (en) 1994-09-07
CZ284034B6 (cs) 1998-07-15
HU219225B (en) 2001-03-28
KR100248365B1 (ko) 2000-04-01
IL101710A0 (en) 1992-12-30
FI935051A0 (fi) 1993-11-15
DE59208362D1 (de) 1997-05-22
PH31463A (en) 1998-11-03
HUT67321A (en) 1995-03-28
DK0584126T3 (da) 1997-10-20
IL101710A (en) 1998-03-10
AU658626B2 (en) 1995-04-27
CA2103060A1 (en) 1992-11-16
IE921538A1 (en) 1992-11-18
ATE151643T1 (de) 1997-05-15
FI935051A (fi) 1993-11-15
JP2547301B2 (ja) 1996-10-23
HU9303230D0 (en) 1994-03-28
MY131090A (en) 2007-07-31
FI107705B (fi) 2001-09-28
ES2103369T3 (es) 1997-09-16
JPH06503581A (ja) 1994-04-21
WO1992020378A1 (de) 1992-11-26
YU47192A (sh) 1997-08-22
NO934107L (no) 1993-11-12
US5492698A (en) 1996-02-20
GR3024015T3 (en) 1997-10-31
EP0584126A1 (de) 1994-03-02
CZ238093A3 (en) 1994-03-16
DE4115849A1 (de) 1992-11-19
IE80626B1 (en) 1998-10-21
AU1670992A (en) 1992-12-30
NZ242722A (en) 1994-10-26
NO306762B1 (no) 1999-12-20
CA2103060C (en) 1999-11-30
NO934107D0 (no) 1993-11-12
EP0584126B1 (de) 1997-04-16

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