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Application filed by "Биовет" АдfiledCritical"Биовет" Ад
Priority to BG100447ApriorityCriticalpatent/BG62168B1/en
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Publication of BG62168B1publicationCriticalpatent/BG62168B1/en
Preparation Of Compounds By Using Micro-Organisms
(AREA)
Micro-Organisms Or Cultivation Processes Thereof
(AREA)
Steroid Compounds
(AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
The strain is used in the pharmaceutical industry for the preparation of hypocholesterolimic product of the group of A lactones used in medicine as an agent for the adjustment of the cholesterin content in blood. Strain Aspergillus terreus is produced by mutagenous treatment of the initial Aspergillus terreus, NBIMCC No. 3319, by treatment with UV light, selection of specific variant of the strain after resowing, natural selection and subsequent treatment with N-methyl-N'-nitro-N-nitrosoguanadine. Mutant having considerably increased productive potentials of the desired hypocholesterollimic product is produced.
BG100447A1996-03-221996-03-22Strain aspergillus terreus, producent of hypocholesterolimic product
BG62168B1
(en)
Pharmaceutical compositions containing L-carnitine or derivatives thereof in combination with resveratrol or derivatives thereof, for the prophylaxis and treatment of cardiovascular disorders, peripheral vascular diseases and peripheral diabetic neuropathy