HUP9802314A2 - Pure 3r-3'r stereoisomer of zeaxanthin for treating macular degeneration in humans - Google Patents
Pure 3r-3'r stereoisomer of zeaxanthin for treating macular degeneration in humansInfo
- Publication number
- HUP9802314A2 HUP9802314A2 HU9802314A HUP9802314A HUP9802314A2 HU P9802314 A2 HUP9802314 A2 HU P9802314A2 HU 9802314 A HU9802314 A HU 9802314A HU P9802314 A HUP9802314 A HU P9802314A HU P9802314 A2 HUP9802314 A2 HU P9802314A2
- Authority
- HU
- Hungary
- Prior art keywords
- zeaxanthin
- humans
- macular degeneration
- pure
- stereoisomer
- Prior art date
Links
- JKQXZKUSFCKOGQ-JLGXGRJMSA-N (3R,3'R)-beta,beta-carotene-3,3'-diol Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-JLGXGRJMSA-N 0.000 title abstract 3
- JKQXZKUSFCKOGQ-LQFQNGICSA-N Z-zeaxanthin Natural products C([C@H](O)CC=1C)C(C)(C)C=1C=CC(C)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C=CC1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-LQFQNGICSA-N 0.000 title abstract 3
- QOPRSMDTRDMBNK-RNUUUQFGSA-N Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCC(O)C1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C QOPRSMDTRDMBNK-RNUUUQFGSA-N 0.000 title abstract 3
- JKQXZKUSFCKOGQ-LOFNIBRQSA-N all-trans-Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C JKQXZKUSFCKOGQ-LOFNIBRQSA-N 0.000 title abstract 3
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 title abstract 3
- 229940043269 zeaxanthin Drugs 0.000 title abstract 3
- 235000010930 zeaxanthin Nutrition 0.000 title abstract 3
- 239000001775 zeaxanthin Substances 0.000 title abstract 3
- 208000002780 macular degeneration Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000015872 dietary supplement Nutrition 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 210000001525 retina Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- General Chemical & Material Sciences (AREA)
- Botany (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A találmány a zeaxantinnak nevezett karőtinőid 3R-3' Rsztereőizőmerjének tiszta főrmában való előállítására és gyógyszerkéntvagy tápanyagkiegészítőként emberben a retina kárősődását őkőzómakűláris degeneráció kezelésére történik, az alkalmazáshőz tisztítőttés részlegesen tisztítőtt zeaxantin is használható. ŕThe invention is for the production of the 3R-3' Rstereostimulatory compound called zeaxanthin in its pure form and as a medicine or nutritional supplement for the treatment of macular degeneration, which is a damage to the retina in humans, partially purified zeaxanthin can also be used. ŕ
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/551,153 US5827652A (en) | 1995-10-31 | 1995-10-31 | Zeaxanthin formulations for human ingestion |
US08/551,166 US5854015A (en) | 1995-10-31 | 1995-10-31 | Method of making pure 3R-3'R stereoisomer of zeaxanthin for human ingestion |
PCT/US1996/017563 WO1997016175A1 (en) | 1995-10-31 | 1996-10-30 | Pure 3r-3'r stereoisomer of zeaxanthin for treating macular degeneration in humans |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP9802314A2 true HUP9802314A2 (en) | 1999-04-28 |
HUP9802314A3 HUP9802314A3 (en) | 1999-05-28 |
HU223208B1 HU223208B1 (en) | 2004-03-29 |
Family
ID=27069666
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9802314A HU223208B1 (en) | 1995-10-31 | 1996-10-30 | Use of pure 3r-3'r stereoisomer of zeaxanthin for preparation of pharmaceuticals or foodstoffs for treating macular degeneration in humans |
Country Status (14)
Country | Link |
---|---|
JP (1) | JPH10512594A (en) |
KR (1) | KR100570251B1 (en) |
CN (1) | CN1104235C (en) |
AR (1) | AR004245A1 (en) |
AU (1) | AU710634B2 (en) |
BR (1) | BR9611488A (en) |
CZ (1) | CZ297575B6 (en) |
FI (1) | FI980947A (en) |
HU (1) | HU223208B1 (en) |
NO (1) | NO981698L (en) |
PL (1) | PL185465B1 (en) |
RU (1) | RU2197958C2 (en) |
WO (1) | WO1997016175A1 (en) |
ZA (1) | ZA969139B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8088363B2 (en) * | 2002-10-28 | 2012-01-03 | Zeavision Llc | Protection against sunburn and skin problems with orally-ingested high-dosage zeaxanthin |
GB0501365D0 (en) * | 2005-01-21 | 2005-03-02 | Promar As | Compositions |
WO2006086706A2 (en) * | 2005-02-11 | 2006-08-17 | Kalamazoo Holdings, Inc. | A capsicum variety exhibiting a hyper-accumulation of zeaxanthin and products derived therefrom |
US8592662B2 (en) | 2005-02-11 | 2013-11-26 | Kalamazoo Holdings, Inc. | Capsicum variety exhibiting a hyper-accumulation of zeaxanthin and products derived therefrom |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US308759A (en) * | 1884-12-02 | Curling hat-brims and machine therefor | ||
EP0534955B1 (en) * | 1989-08-30 | 1997-05-28 | Applied Food Biotechnology, Inc. | Process for the production of a zeaxanthin-containing composition using a microorganism of the species Flavobacterium multivorum |
US5310764A (en) * | 1992-05-08 | 1994-05-10 | Steven Baranowitz | Treatment of age related macular degeneration with beta-carotene |
-
1996
- 1996-10-30 BR BR9611488A patent/BR9611488A/en not_active Application Discontinuation
- 1996-10-30 PL PL96326558A patent/PL185465B1/en unknown
- 1996-10-30 AU AU70501/96A patent/AU710634B2/en not_active Ceased
- 1996-10-30 HU HU9802314A patent/HU223208B1/en not_active IP Right Cessation
- 1996-10-30 RU RU98110058/14A patent/RU2197958C2/en not_active IP Right Cessation
- 1996-10-30 CZ CZ0130998A patent/CZ297575B6/en not_active IP Right Cessation
- 1996-10-30 CN CN96198014A patent/CN1104235C/en not_active Expired - Fee Related
- 1996-10-30 ZA ZA9609139A patent/ZA969139B/en unknown
- 1996-10-30 KR KR1019980703131A patent/KR100570251B1/en not_active IP Right Cessation
- 1996-10-30 JP JP9517583A patent/JPH10512594A/en active Pending
- 1996-10-30 WO PCT/US1996/017563 patent/WO1997016175A1/en active IP Right Grant
- 1996-10-31 AR ARP960104982A patent/AR004245A1/en unknown
-
1998
- 1998-04-16 NO NO981698A patent/NO981698L/en not_active Application Discontinuation
- 1998-04-29 FI FI980947A patent/FI980947A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
MX9605248A (en) | 1998-06-30 |
AR004245A1 (en) | 1998-11-04 |
AU710634B2 (en) | 1999-09-23 |
FI980947A0 (en) | 1996-10-30 |
CZ130998A3 (en) | 1998-07-15 |
HU223208B1 (en) | 2004-03-29 |
ZA969139B (en) | 1997-09-25 |
CZ297575B6 (en) | 2007-02-07 |
KR19990067180A (en) | 1999-08-16 |
HUP9802314A3 (en) | 1999-05-28 |
JPH10512594A (en) | 1998-12-02 |
NO981698D0 (en) | 1998-04-16 |
PL326558A1 (en) | 1998-09-28 |
CN1104235C (en) | 2003-04-02 |
FI980947A (en) | 1998-04-29 |
AU7050196A (en) | 1997-05-08 |
BR9611488A (en) | 1999-01-19 |
KR100570251B1 (en) | 2006-06-21 |
NO981698L (en) | 1998-06-08 |
CN1201388A (en) | 1998-12-09 |
PL185465B1 (en) | 2003-05-30 |
RU2197958C2 (en) | 2003-02-10 |
WO1997016175A1 (en) | 1997-05-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HFG4 | Patent granted, date of granting |
Effective date: 20040216 |
|
MM4A | Lapse of definitive patent protection due to non-payment of fees |