ZA921369B - Novel poly-iodinated compounds, process for their preparation, contrast medium containing them. - Google Patents

Novel poly-iodinated compounds, process for their preparation, contrast medium containing them.

Info

Publication number
ZA921369B
ZA921369B ZA921369A ZA921369A ZA921369B ZA 921369 B ZA921369 B ZA 921369B ZA 921369 A ZA921369 A ZA 921369A ZA 921369 A ZA921369 A ZA 921369A ZA 921369 B ZA921369 B ZA 921369B
Authority
ZA
South Africa
Prior art keywords
preparation
medium containing
contrast medium
novel poly
iodinated compounds
Prior art date
Application number
ZA921369A
Other languages
English (en)
Inventor
Maryse Dugast-Zrihen
Dominique Meyer
Original Assignee
Guerbet Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guerbet Sa filed Critical Guerbet Sa
Publication of ZA921369B publication Critical patent/ZA921369B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/16—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Liquid Crystal Substances (AREA)
ZA921369A 1991-02-25 1992-02-25 Novel poly-iodinated compounds, process for their preparation, contrast medium containing them. ZA921369B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR919102226A FR2673180B1 (fr) 1991-02-25 1991-02-25 Nouveaux composes non ioniques poly-iodes, procede de preparation, produit de contraste les contenant.

Publications (1)

Publication Number Publication Date
ZA921369B true ZA921369B (en) 1993-08-25

Family

ID=9410062

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA921369A ZA921369B (en) 1991-02-25 1992-02-25 Novel poly-iodinated compounds, process for their preparation, contrast medium containing them.

Country Status (19)

Country Link
US (1) US5616798A (da)
EP (1) EP0501875B1 (da)
JP (1) JPH06505267A (da)
AT (1) ATE106864T1 (da)
AU (1) AU654341B2 (da)
CA (1) CA2104786A1 (da)
CZ (1) CZ173693A3 (da)
DE (1) DE69200168T2 (da)
DK (1) DK0501875T3 (da)
ES (1) ES2055637T3 (da)
FR (1) FR2673180B1 (da)
IE (1) IE66594B1 (da)
IL (1) IL101064A0 (da)
MX (1) MX9200790A (da)
NO (1) NO932992L (da)
NZ (1) NZ241725A (da)
SK (1) SK89393A3 (da)
WO (1) WO1992014695A1 (da)
ZA (1) ZA921369B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0731786B1 (en) * 1993-12-03 1998-10-21 BRACCO S.p.A. Biphenyl iodinated derivatives and their diagnostic use
DE69510460T2 (de) * 1994-09-22 2000-01-13 Guerbet, Villepinte Iodo-verbindungen, ihre herstellung und verwendung als kontrastmittel für röntgen-radiologie
US6310243B1 (en) * 1994-09-23 2001-10-30 Nycomed Imaging As Iodinated x-ray contrast media
GB9419203D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
GB9419206D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
IT1271134B (it) * 1994-12-01 1997-05-26 Bracco Spa Derivati iodurati del bifenile e loro impiego diagnostico
US5575905A (en) * 1995-05-24 1996-11-19 Nycomed Imaging As Iodination process
US6265610B1 (en) 1999-01-12 2001-07-24 The University Of North Carolina At Chapel Hill Contrast media for angiography
ATE298320T1 (de) * 1999-04-30 2005-07-15 Amersham Health As Kontrastmittel
US6981817B2 (en) * 2003-07-17 2006-01-03 Braverman Josef J Base unit for road delineating devices
DE102007058220A1 (de) 2007-12-03 2009-06-04 Bayer Schering Pharma Aktiengesellschaft Dimere macrocyclisch substituierte Benzolderivate
EP2093206A1 (en) 2008-02-20 2009-08-26 BRACCO IMAGING S.p.A. Process for the iodination of aromatic compounds
EP2243767A1 (en) 2009-04-21 2010-10-27 Bracco Imaging S.p.A Process for the iodination of aromatic compounds
SG177308A1 (en) * 2009-06-22 2012-02-28 Hoffmann La Roche Novel biphenyl and phenyl-pyridine amides
DK2451994T3 (da) 2009-07-07 2014-01-20 Bracco Imaging Spa Fremgangsmåde til fremstilling af et ioderende middel
EP2394984A1 (en) 2010-06-10 2011-12-14 Bracco Imaging S.p.A Process for the iodination of phenolic derivatives
EP2700645A4 (en) 2011-04-20 2014-09-24 Kemphys Ltd SILICONE-CONTAINING CARBOXYLENE DERIVATIVE
US10918742B2 (en) 2016-03-25 2021-02-16 Nanoprobes, Inc. Iodine-based particles

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4102924A (en) * 1973-10-25 1978-07-25 Bayer Aktiengesellschaft Process for the preparation of diaryl compounds
IT1207226B (it) * 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
FR2541676A1 (fr) * 1983-02-25 1984-08-31 Guerbet Sa Composes non-ioniques a structures benzenique iodee ou bromee et produits opacifiants en contenant
DE3429949A1 (de) * 1984-08-10 1986-02-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue nicht -ionische 2,4,6-trijod-isophthalsaeure-bis-amide, verfahren zu ihrer herstellung und ihre verwendung als roentgenkontrastmittel
DE3731542A1 (de) * 1987-09-17 1989-03-30 Schering Ag Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
IL90326A (en) * 1988-06-02 1993-05-13 Guerbet Sa Non-ionic triiodobenzene compounds and contrast media containing them
US5232685A (en) * 1989-11-03 1993-08-03 Schering Aktiengesellschaft Nonionic x-ray contrast medium with high iodine content

Also Published As

Publication number Publication date
NO932992L (no) 1993-10-25
IL101064A0 (en) 1992-11-15
FR2673180A1 (fr) 1992-08-28
EP0501875B1 (fr) 1994-06-08
NO932992D0 (no) 1993-08-23
CZ173693A3 (en) 1994-02-16
AU654341B2 (en) 1994-11-03
DE69200168T2 (de) 1994-10-20
US5616798A (en) 1997-04-01
WO1992014695A1 (fr) 1992-09-03
FR2673180B1 (fr) 1994-03-04
AU1413592A (en) 1992-09-15
IE920585A1 (en) 1992-08-26
IE66594B1 (en) 1996-01-24
DK0501875T3 (da) 1994-10-10
CA2104786A1 (fr) 1992-08-26
DE69200168D1 (de) 1994-07-14
ATE106864T1 (de) 1994-06-15
JPH06505267A (ja) 1994-06-16
MX9200790A (es) 1992-08-01
ES2055637T3 (es) 1994-08-16
NZ241725A (en) 1994-10-26
SK89393A3 (en) 1994-04-06
EP0501875A1 (fr) 1992-09-02

Similar Documents

Publication Publication Date Title
ZA921369B (en) Novel poly-iodinated compounds, process for their preparation, contrast medium containing them.
PH18301A (en) Novel triiodinated isophthalic acid diamides as nonionic x-ray contrast media
IL99775A0 (en) Antimicrobial agents containing substituted 2-cyclohexan-1-yl-amino derivatives,certain such novel compounds and their preparation
IL104814A0 (en) Polyiodinated nonionic compounds,their preparation and their use as contrast agents for radiography
DE69020208D1 (de) Kontrastmittel.
GR3023934T3 (en) New naphthalene amides and sulfonamides, process for their preparation and pharmaceutical compositions containing them
JPS6419066A (en) Dihydropyridineamides
ATE37533T1 (de) Derivate der 4-phenyl-4-oxo-buten-2-saeure, verfahren zu ihrer herstellung, medikamente und mischungen mit diesen derivaten.
FI885295A0 (fi) Substituoituja dikarboksyylihappo-bis(3,5-dikarbamoyyli-2,4,6-trijodianilideja) menetelmä niiden valmistamiseksi sekä niiden käyttö röntgenvarjoaineiden valmistamiseksi
GR3015576T3 (en) Use of 2-n-alkyl-1,2-benzisothiazolin-3-ones as technical microbiocides.
IL108856A0 (en) Hydroxymethyl-furazancarboxylic acid derivatives, their preparation and pharmaceutical compositions containing them
FI102745B1 (fi) Uusia jodattuja ei-ionisia trijodibentseeniyhdisteitä ja niitä sisältäviä varjoaineita
DK0437144T3 (da) Ikke-ionisk iodholdige sammensætninger, fremgangsmåde til deres fremstilling og kontrastmidler indeholdende dem
ATE19244T1 (de) 2-piperazinyl-4-phenyl-quinazolin-derivate mit antidepressiven eigenschaften, verfahren zu deren herstellung und diese enthaltende arzneimitteln.
ES2123739T3 (es) Nuevos analogos del eburnano, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
DK0552631T3 (da) Alfa-Aryl-alfa-hydroxy-beta-imidazolinyl-propionsyreamider
ES8504688A1 (es) Procedimiento para la obtencion de esteres del acido halogenoalquilcarbamico
GR3006202T3 (da)