NO932992L - Nye polyjoderte forbindelser, fremgangsmaate for deres fremstilling og kontrastmidler inneholdende dem - Google Patents

Nye polyjoderte forbindelser, fremgangsmaate for deres fremstilling og kontrastmidler inneholdende dem

Info

Publication number
NO932992L
NO932992L NO93932992A NO932992A NO932992L NO 932992 L NO932992 L NO 932992L NO 93932992 A NO93932992 A NO 93932992A NO 932992 A NO932992 A NO 932992A NO 932992 L NO932992 L NO 932992L
Authority
NO
Norway
Prior art keywords
compounds
preparation
new
polyjoded
contractors
Prior art date
Application number
NO93932992A
Other languages
English (en)
Other versions
NO932992D0 (no
Inventor
Maryse Dugast-Zrihen
Dominique Meyer
Original Assignee
Guerbet Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guerbet Sa filed Critical Guerbet Sa
Publication of NO932992D0 publication Critical patent/NO932992D0/no
Publication of NO932992L publication Critical patent/NO932992L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/16—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Pyrrole Compounds (AREA)
  • Liquid Crystal Substances (AREA)

Abstract

Nye polyjoderte forbindelser med generell formel (I) hvor R1, R2, R3, R4, R5, R6, R7, R8, R9 og R10 er like eller forskjellige og er valgt fra et jodatom, en gruppe med formelen (a) og en gruppe med formelen b) med den betingelse at minst to grupper blant R,, R2, R3, R,, R5, R6, R,, R8. R, og R10 er et jodatom. Forbindelsene kan anvendes i rontgenkontrastmidler. En fremgangsmåte for fremstilling av forbindelsene og et kon- trastmiddel inneholdende disse er også beskrevet.
NO93932992A 1991-02-25 1993-08-23 Nye polyjoderte forbindelser, fremgangsmaate for deres fremstilling og kontrastmidler inneholdende dem NO932992L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR919102226A FR2673180B1 (fr) 1991-02-25 1991-02-25 Nouveaux composes non ioniques poly-iodes, procede de preparation, produit de contraste les contenant.
PCT/FR1992/000172 WO1992014695A1 (fr) 1991-02-25 1992-02-25 Nouveaux composes poly-iodes, procede de preparation, produit de contraste les contenant

Publications (2)

Publication Number Publication Date
NO932992D0 NO932992D0 (no) 1993-08-23
NO932992L true NO932992L (no) 1993-10-25

Family

ID=9410062

Family Applications (1)

Application Number Title Priority Date Filing Date
NO93932992A NO932992L (no) 1991-02-25 1993-08-23 Nye polyjoderte forbindelser, fremgangsmaate for deres fremstilling og kontrastmidler inneholdende dem

Country Status (19)

Country Link
US (1) US5616798A (no)
EP (1) EP0501875B1 (no)
JP (1) JPH06505267A (no)
AT (1) ATE106864T1 (no)
AU (1) AU654341B2 (no)
CA (1) CA2104786A1 (no)
CZ (1) CZ173693A3 (no)
DE (1) DE69200168T2 (no)
DK (1) DK0501875T3 (no)
ES (1) ES2055637T3 (no)
FR (1) FR2673180B1 (no)
IE (1) IE66594B1 (no)
IL (1) IL101064A0 (no)
MX (1) MX9200790A (no)
NO (1) NO932992L (no)
NZ (1) NZ241725A (no)
SK (1) SK89393A3 (no)
WO (1) WO1992014695A1 (no)
ZA (1) ZA921369B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE172449T1 (de) * 1993-12-03 1998-11-15 Bracco Spa Biphenyl jodierte derivate und ihre verwendung als diagnostikum
JPH10505851A (ja) * 1994-09-22 1998-06-09 ゲルベ・ソシエテ・アノニム ポリヨウ素化化合物、その製法、およびｘ線放射線医学におけるその使用
GB9419206D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
GB9419203D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
US6310243B1 (en) * 1994-09-23 2001-10-30 Nycomed Imaging As Iodinated x-ray contrast media
IT1271134B (it) * 1994-12-01 1997-05-26 Bracco Spa Derivati iodurati del bifenile e loro impiego diagnostico
US5575905A (en) * 1995-05-24 1996-11-19 Nycomed Imaging As Iodination process
US6265610B1 (en) 1999-01-12 2001-07-24 The University Of North Carolina At Chapel Hill Contrast media for angiography
JP4582918B2 (ja) * 1999-04-30 2010-11-17 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
US6981817B2 (en) * 2003-07-17 2006-01-03 Braverman Josef J Base unit for road delineating devices
DE102007058220A1 (de) 2007-12-03 2009-06-04 Bayer Schering Pharma Aktiengesellschaft Dimere macrocyclisch substituierte Benzolderivate
EP2093206A1 (en) 2008-02-20 2009-08-26 BRACCO IMAGING S.p.A. Process for the iodination of aromatic compounds
EP2243767A1 (en) 2009-04-21 2010-10-27 Bracco Imaging S.p.A Process for the iodination of aromatic compounds
EP2445868B1 (en) * 2009-06-22 2013-12-18 F.Hoffmann-La Roche Ag Biphenyl amides useful as p2x3 and/or p2x2/3 receptors modulators
CA2763405C (en) 2009-07-07 2013-09-10 Bracco Imaging Spa Process for the preparation of a iodinating agent
EP2394984A1 (en) 2010-06-10 2011-12-14 Bracco Imaging S.p.A Process for the iodination of phenolic derivatives
US8895769B2 (en) 2011-04-20 2014-11-25 Kemphys Ltd. Silicon-containing carboxylic acid derivative
WO2017165841A1 (en) 2016-03-25 2017-09-28 Nanoprobes, Inc. Iodine-based particles

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4102924A (en) * 1973-10-25 1978-07-25 Bayer Aktiengesellschaft Process for the preparation of diaryl compounds
IT1207226B (it) * 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
FR2541676A1 (fr) * 1983-02-25 1984-08-31 Guerbet Sa Composes non-ioniques a structures benzenique iodee ou bromee et produits opacifiants en contenant
DE3429949A1 (de) * 1984-08-10 1986-02-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue nicht -ionische 2,4,6-trijod-isophthalsaeure-bis-amide, verfahren zu ihrer herstellung und ihre verwendung als roentgenkontrastmittel
DE3731542A1 (de) * 1987-09-17 1989-03-30 Schering Ag Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
IL90326A (en) * 1988-06-02 1993-05-13 Guerbet Sa Non-ionic triiodobenzene compounds and contrast media containing them
US5232685A (en) * 1989-11-03 1993-08-03 Schering Aktiengesellschaft Nonionic x-ray contrast medium with high iodine content

Also Published As

Publication number Publication date
ES2055637T3 (es) 1994-08-16
IE920585A1 (en) 1992-08-26
FR2673180A1 (fr) 1992-08-28
US5616798A (en) 1997-04-01
NO932992D0 (no) 1993-08-23
DE69200168D1 (de) 1994-07-14
IE66594B1 (en) 1996-01-24
CZ173693A3 (en) 1994-02-16
AU1413592A (en) 1992-09-15
NZ241725A (en) 1994-10-26
WO1992014695A1 (fr) 1992-09-03
FR2673180B1 (fr) 1994-03-04
ATE106864T1 (de) 1994-06-15
DE69200168T2 (de) 1994-10-20
MX9200790A (es) 1992-08-01
AU654341B2 (en) 1994-11-03
SK89393A3 (en) 1994-04-06
CA2104786A1 (fr) 1992-08-26
JPH06505267A (ja) 1994-06-16
EP0501875B1 (fr) 1994-06-08
DK0501875T3 (da) 1994-10-10
IL101064A0 (en) 1992-11-15
EP0501875A1 (fr) 1992-09-02
ZA921369B (en) 1993-08-25

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