ZA919196B - New and useful excitatory amino acid antagonist - Google Patents

New and useful excitatory amino acid antagonist

Info

Publication number
ZA919196B
ZA919196B ZA919196A ZA919196A ZA919196B ZA 919196 B ZA919196 B ZA 919196B ZA 919196 A ZA919196 A ZA 919196A ZA 919196 A ZA919196 A ZA 919196A ZA 919196 B ZA919196 B ZA 919196B
Authority
ZA
South Africa
Prior art keywords
amino acid
excitatory amino
useful
new
acid antagonist
Prior art date
Application number
ZA919196A
Other languages
English (en)
Inventor
Greg Scott Hamilton
Scott Hamilton Greg
Original Assignee
Nova Pharm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nova Pharm Corp filed Critical Nova Pharm Corp
Publication of ZA919196B publication Critical patent/ZA919196B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/383Cycloaliphatic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4018Esters of cycloaliphatic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503Five-membered rings
    • C07F9/6506Five-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA919196A 1990-12-07 1991-11-20 New and useful excitatory amino acid antagonist ZA919196B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62416890A 1990-12-07 1990-12-07

Publications (1)

Publication Number Publication Date
ZA919196B true ZA919196B (en) 1992-09-30

Family

ID=24500939

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA919196A ZA919196B (en) 1990-12-07 1991-11-20 New and useful excitatory amino acid antagonist

Country Status (11)

Country Link
EP (1) EP0639197B1 (de)
JP (1) JP2721933B2 (de)
AT (1) ATE142220T1 (de)
CA (1) CA2097910A1 (de)
DE (1) DE69121920T2 (de)
DK (1) DK0639197T3 (de)
ES (1) ES2094338T3 (de)
GR (1) GR3021881T3 (de)
IE (1) IE75735B1 (de)
WO (1) WO1992010099A1 (de)
ZA (1) ZA919196B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6028213A (en) * 1998-04-16 2000-02-22 Eastman Chemical Company Optically active cis-1,3-cyclohexanedicarboxylic acid monoesters with high enantiomeric purity and process for their preparation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4761405A (en) * 1987-03-04 1988-08-02 Nova Pharmaceutical Corporation Antagonists of specific excitatory amino acid neurotransmitter receptors having increased potency

Also Published As

Publication number Publication date
DE69121920T2 (de) 1997-04-03
ATE142220T1 (de) 1996-09-15
EP0639197A1 (de) 1995-02-22
JPH06505966A (ja) 1994-07-07
IE914256A1 (en) 1992-06-17
DK0639197T3 (de) 1997-02-24
DE69121920D1 (de) 1996-10-10
GR3021881T3 (en) 1997-03-31
CA2097910A1 (en) 1992-06-08
EP0639197A4 (de) 1994-02-21
WO1992010099A1 (en) 1992-06-25
ES2094338T3 (es) 1997-01-16
IE75735B1 (en) 1997-09-24
JP2721933B2 (ja) 1998-03-04
EP0639197B1 (de) 1996-09-04

Similar Documents

Publication Publication Date Title
EA199700260A1 (ru) Готовая препаративная форма 2-метилтиенобензодиазепина для перорального введения и способ ее получения
LU91145I2 (fr) FIROCOXIB facultativement sous forme d'un sel pharmaceutiquement acceptable (PREVICOX).
PL288592A1 (en) Method of obtaining novel derivatives of 3-aminopiperidine
KR900012911A (ko) 흥분성 아미노산 수용기 길항질 화합물
YU104690A (sh) Supstituisani imidazo-kondenzovani 6-člani heterocikli kao antagonisti angiotenzina 2
RU93046497A (ru) Фенильные гетероциклические производные, способ их получения, фармацевтическая композиция и промежуточный продукт
UA66750C2 (en) Substituted 1-phenylpirazole 3-carboxamides, a method for the preparation thereof and intermediary compounds, pharmaceutical composition having affinity to neurotensin receptors
IT1137271B (it) Mercaptoacil derivati di varie proline 4 sostituite e relative composizioni utili per il trattamento dell'ipertensione
NO944578L (no) Eksitatoriske aminosyre reseptor antagonister
AU7166787A (en) Antagonists of specific excitatory amino acid neurotransmitter receptors
HUT55369A (en) Herbicidal compositions and process for producing sulfonylamino-carbonyl triazolinone derivatives and their intermediates used as active ingredient
MX9801890A (es) Nuevos compuestos antagonistas selectivos del receptor nk3 humano, procedimiento para su obtencion y composiciones farmaceuticas que los contienen.
PT927184E (pt) Derivados de pirido-¬4',3':4,5|-tieno-¬2,3-d|-pirimidina 3-substituidos a sua producao e a sua utilizacao
CA2087091A1 (en) Excitatory amino acid antagonists
IL94377A (en) Pyridine derivatives which antagonize the effects of excitatory amino acids upon the nmda receptor complex and pharmaceutical compositions comprising them
FI93210B (fi) Menetelmä virusvastaisen yhdisteen valmistamiseksi
DK0617616T3 (da) Potensering af NMDA-antagonister
HUT57197A (en) Process for producing iminothiazoline derivatives and their intermediates, as well as herbicidal compositions comprising iminothiazoline derivatives as active ingredient
DK0639197T3 (de)
MX9708557A (es) Nuevo uso farmacologico de los antagonistas del receptor aii.
UA41300C2 (uk) Аналоги гормонів-антагоністів lhrh і спосіб їх отримання
AU8653891A (en) Amino acid analogs as cck antagonists
ATE79540T1 (de) Pharmazeutische zusammensetzung.
DK0552712T3 (da) 8-(1-aminocycloalkyl)1,3-dialkylxanthinderivater som antagonister for adenosinreceptorer
ZA916918B (en) Amino acid analogs as CCK antagonists.