DE69121920T2 - Antagonisten reizübertragender aminosäuren - Google Patents
Antagonisten reizübertragender aminosäurenInfo
- Publication number
- DE69121920T2 DE69121920T2 DE69121920T DE69121920T DE69121920T2 DE 69121920 T2 DE69121920 T2 DE 69121920T2 DE 69121920 T DE69121920 T DE 69121920T DE 69121920 T DE69121920 T DE 69121920T DE 69121920 T2 DE69121920 T2 DE 69121920T2
- Authority
- DE
- Germany
- Prior art keywords
- irritrating
- antagonists
- amino acids
- isomer
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 150000001413 amino acids Chemical class 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 102000018899 Glutamate Receptors Human genes 0.000 abstract 1
- 108010027915 Glutamate Receptors Proteins 0.000 abstract 1
- 239000003194 amino acid receptor blocking agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/383—Cycloaliphatic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4018—Esters of cycloaliphatic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62416890A | 1990-12-07 | 1990-12-07 | |
| PCT/US1991/008834 WO1992010099A1 (en) | 1990-12-07 | 1991-12-04 | Excitatory amino acid antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69121920D1 DE69121920D1 (de) | 1996-10-10 |
| DE69121920T2 true DE69121920T2 (de) | 1997-04-03 |
Family
ID=24500939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69121920T Expired - Fee Related DE69121920T2 (de) | 1990-12-07 | 1991-12-04 | Antagonisten reizübertragender aminosäuren |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0639197B1 (de) |
| JP (1) | JP2721933B2 (de) |
| AT (1) | ATE142220T1 (de) |
| CA (1) | CA2097910A1 (de) |
| DE (1) | DE69121920T2 (de) |
| DK (1) | DK0639197T3 (de) |
| ES (1) | ES2094338T3 (de) |
| GR (1) | GR3021881T3 (de) |
| IE (1) | IE75735B1 (de) |
| WO (1) | WO1992010099A1 (de) |
| ZA (1) | ZA919196B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6028213A (en) | 1998-04-16 | 2000-02-22 | Eastman Chemical Company | Optically active cis-1,3-cyclohexanedicarboxylic acid monoesters with high enantiomeric purity and process for their preparation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4761405A (en) * | 1987-03-04 | 1988-08-02 | Nova Pharmaceutical Corporation | Antagonists of specific excitatory amino acid neurotransmitter receptors having increased potency |
-
1991
- 1991-11-20 ZA ZA919196A patent/ZA919196B/xx unknown
- 1991-12-04 AT AT92901599T patent/ATE142220T1/de not_active IP Right Cessation
- 1991-12-04 CA CA002097910A patent/CA2097910A1/en not_active Abandoned
- 1991-12-04 ES ES92901599T patent/ES2094338T3/es not_active Expired - Lifetime
- 1991-12-04 DK DK92901599.8T patent/DK0639197T3/da active
- 1991-12-04 WO PCT/US1991/008834 patent/WO1992010099A1/en active IP Right Grant
- 1991-12-04 JP JP4502346A patent/JP2721933B2/ja not_active Expired - Lifetime
- 1991-12-04 DE DE69121920T patent/DE69121920T2/de not_active Expired - Fee Related
- 1991-12-04 EP EP92901599A patent/EP0639197B1/de not_active Expired - Lifetime
- 1991-12-06 IE IE425691A patent/IE75735B1/en not_active IP Right Cessation
-
1996
- 1996-12-04 GR GR960403296T patent/GR3021881T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69121920D1 (de) | 1996-10-10 |
| EP0639197A1 (de) | 1995-02-22 |
| CA2097910A1 (en) | 1992-06-08 |
| ATE142220T1 (de) | 1996-09-15 |
| IE914256A1 (en) | 1992-06-17 |
| DK0639197T3 (de) | 1997-02-24 |
| ZA919196B (en) | 1992-09-30 |
| JP2721933B2 (ja) | 1998-03-04 |
| ES2094338T3 (es) | 1997-01-16 |
| EP0639197A4 (de) | 1994-02-21 |
| WO1992010099A1 (en) | 1992-06-25 |
| IE75735B1 (en) | 1997-09-24 |
| GR3021881T3 (en) | 1997-03-31 |
| JPH06505966A (ja) | 1994-07-07 |
| EP0639197B1 (de) | 1996-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |