ZA917003B - Novel thiazolidine derivatives - Google Patents

Novel thiazolidine derivatives

Info

Publication number
ZA917003B
ZA917003B ZA917003A ZA917003A ZA917003B ZA 917003 B ZA917003 B ZA 917003B ZA 917003 A ZA917003 A ZA 917003A ZA 917003 A ZA917003 A ZA 917003A ZA 917003 B ZA917003 B ZA 917003B
Authority
ZA
South Africa
Prior art keywords
thiazolidine derivatives
novel thiazolidine
novel
derivatives
thiazolidine
Prior art date
Application number
ZA917003A
Other languages
English (en)
Inventor
Jan Bron
Bron Jan
Geert Jan Sterk
Jan Sterk Geert
Jan Fetze Van Der Werf
Fetze Van Der Werf Jan
Hendrik Timmerman
Timmerman Hendrik
Original Assignee
Cedona Pharm Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cedona Pharm Bv filed Critical Cedona Pharm Bv
Publication of ZA917003B publication Critical patent/ZA917003B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA917003A 1990-09-05 1991-09-04 Novel thiazolidine derivatives ZA917003B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL9001955A NL9001955A (nl) 1990-09-05 1990-09-05 Nieuwe thiazolidinederivaten.

Publications (1)

Publication Number Publication Date
ZA917003B true ZA917003B (en) 1993-04-28

Family

ID=19857632

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA917003A ZA917003B (en) 1990-09-05 1991-09-04 Novel thiazolidine derivatives

Country Status (12)

Country Link
US (1) US5385922A (fr)
EP (1) EP0547104A1 (fr)
JP (1) JPH06500318A (fr)
AU (1) AU656146B2 (fr)
CA (1) CA2089256A1 (fr)
FI (1) FI94754C (fr)
IE (1) IE913103A1 (fr)
IL (1) IL99393A0 (fr)
NL (1) NL9001955A (fr)
NZ (1) NZ239649A (fr)
WO (1) WO1992004337A1 (fr)
ZA (1) ZA917003B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2680173A1 (fr) * 1991-08-07 1993-02-12 Hoechst Lab Nitrates organiques, leurs procedes de preparation et leur utilisation dans le traitement de maladies cardiovasculaires .
WO1994021248A1 (fr) * 1993-03-15 1994-09-29 Byk Nederland Bv Utilisation de nitrates d'alkyle substitues pour le traitement d'un accroissement pathologique de la pression intra-oculaire
WO1995013811A1 (fr) * 1993-11-17 1995-05-26 Byk Nederland Bv Utilisation de derives de thiazolidine substitues pour le traitement de l'elevation de la pression intra-oculaire
BR9506549A (pt) * 1994-01-19 1997-10-14 Byk Nederland Bv Derivados de benzilamina contendo grupos nitróxi e sua aplicação para o tratamento de enfermidades cardiovasculares bem como de pressão interna dos olhos elevada
US5925658A (en) * 1995-03-02 1999-07-20 Sankyo Company, Limited Optically active thiazolidinone derivative
WO1997031896A1 (fr) * 1996-03-01 1997-09-04 Sankyo Company, Limited Derives de thiazolidine
US6083966A (en) * 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
WO2000016763A2 (fr) * 1998-09-21 2000-03-30 University Of Florida Research Foundation, Inc. Agents antipaludeens
ES2142773B1 (es) * 1998-10-07 2001-01-01 Lacer Sa Derivados de mononitrato de isosorbida y su empleo como agentes vasodilatadores con tolerancia desminuida.
WO2005034949A1 (fr) * 2003-09-09 2005-04-21 University Of Florida Derives de desferrithiocine et leur utilisation en tant que chelateurs du fer
CA2603385C (fr) 2005-04-04 2014-07-15 University Of Florida Research Foundation, Inc. Analogues de polyether desferrithiocine et leurs utilisations dans le traitement de conditions telles que la surcharge metallique, la fatigue oxydative et les conditions neoplasiques et pre-neoplasiques
CN104003955A (zh) 2007-03-15 2014-08-27 佛罗里达大学研究基金公司 去铁硫辛聚醚类似物
EP2149576A1 (fr) 2008-07-22 2010-02-03 Lacer, S.A. Nitrates d'isosorbide ayant une activité vasodilatatrice
CN102146062B (zh) * 2011-01-19 2013-04-24 山东大学 噻唑烷类神经氨酸酶抑制剂及其应用
US9061962B2 (en) 2011-10-24 2015-06-23 Nicox Science Ireland Quinone based nitric oxide donating compounds
CN104114170B (zh) 2011-12-16 2021-07-06 佛罗里达大学研究基金会 4′-去铁硫素类似物的用途
RU2526619C2 (ru) * 2012-12-12 2014-08-27 Федеральное государственное бюджетное учреждение науки Институт высокомолекулярных соединений Российской академии наук Способ получения (2r,4r)-2-алкил-3-(2-меркаптобензоил)-1,3-тиазолидин-4-карбоновых кислот
EP2968346B1 (fr) * 2013-03-15 2024-02-07 Cancer Research Technology, LLC Procédés et compositions pour une modulation de cycle gamma-glutamyle
WO2014169976A1 (fr) 2013-04-18 2014-10-23 Nicox Science Ireland Composés donneurs d'oxyde nitrique à base de quinone
EP3071201A4 (fr) 2013-11-22 2017-04-26 University of Florida Research Foundation, Inc. Analogues de la desferrithiocine et leurs utilisations
WO2016176343A1 (fr) 2015-04-27 2016-11-03 University Of Florida Research Foundation, Incorporated Agents chélateurs métalliques programmés métaboliquement et leurs utilisations
CN109516933B (zh) * 2018-10-29 2021-03-02 安徽省庆云医药股份有限公司 一种西洛多辛中间体的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58109461A (ja) * 1981-12-24 1983-06-29 Kowa Co 新規ベンズアミド誘導体
DE3248548A1 (de) * 1982-12-29 1984-07-05 Heinrich Mack Nachf., 7918 Illertissen Acylderivate von 1,4:3,6-dianhydro-hexiten, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3427241A1 (de) * 1984-07-24 1986-02-06 Boehringer Mannheim Gmbh, 6800 Mannheim Amino-propanol-derivate, verwendung derselben und diese enthaltende arzneimittel
DE3433383A1 (de) * 1984-09-12 1986-03-20 Boehringer Mannheim Gmbh, 6800 Mannheim Neue phenyl-acetonitril-derivate
ES8708211A1 (es) * 1985-06-14 1987-10-01 Sankyo Co Un procedimiento para la preparacion de nuevos derivados de 4-(fenil sustituido)-1,4-dihidropiridina.
IT1223565B (it) * 1987-12-21 1990-09-19 Zambon Spa Derivati dell'acido tiazolidin 4 carbossilico ad attivita' farmaceutica
US5025001A (en) * 1988-06-15 1991-06-18 Brigham And Women's Hospital S-nitroso derivatives of ACE inhibitors and the use thereof
JP2628756B2 (ja) * 1988-09-15 1997-07-09 シュバルツファルマ アクチェンゲゼルシャフト 新規有機ニトレート及びそれらの製造方法
NL8802276A (nl) * 1988-09-15 1990-04-02 Cedona Pharm Bv Geneesmiddel met relaxerende werking, dat als aktieve stof een nitraatester bevat.

Also Published As

Publication number Publication date
CA2089256A1 (fr) 1992-03-06
FI930723A (fi) 1993-02-18
JPH06500318A (ja) 1994-01-13
AU8400691A (en) 1992-03-30
EP0547104A1 (fr) 1993-06-23
NL9001955A (nl) 1992-04-01
FI94754B (fi) 1995-07-14
AU656146B2 (en) 1995-01-27
WO1992004337A1 (fr) 1992-03-19
US5385922A (en) 1995-01-31
FI930723A0 (fi) 1993-02-18
NZ239649A (en) 1994-04-27
IE913103A1 (en) 1992-03-11
IL99393A0 (en) 1992-08-18
FI94754C (fi) 1995-10-25

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