ZA916098B - Oxazolidinodione derivatives - Google Patents
Oxazolidinodione derivativesInfo
- Publication number
- ZA916098B ZA916098B ZA916098A ZA916098A ZA916098B ZA 916098 B ZA916098 B ZA 916098B ZA 916098 A ZA916098 A ZA 916098A ZA 916098 A ZA916098 A ZA 916098A ZA 916098 B ZA916098 B ZA 916098B
- Authority
- ZA
- South Africa
- Prior art keywords
- oxazolidinodione
- derivatives
- oxazolidinodione derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/44—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909017218A GB9017218D0 (en) | 1990-08-06 | 1990-08-06 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA916098B true ZA916098B (en) | 1992-09-30 |
Family
ID=10680236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA916098A ZA916098B (en) | 1990-08-06 | 1991-08-02 | Oxazolidinodione derivatives |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5391565A (ja) |
| EP (1) | EP0542816A1 (ja) |
| JP (1) | JPH06500538A (ja) |
| KR (1) | KR930701434A (ja) |
| AU (1) | AU646491B2 (ja) |
| CA (1) | CA2093146A1 (ja) |
| GB (1) | GB9017218D0 (ja) |
| IE (1) | IE912772A1 (ja) |
| MX (1) | MX9100529A (ja) |
| NZ (1) | NZ239265A (ja) |
| PT (1) | PT98577A (ja) |
| TW (1) | TW199156B (ja) |
| WO (1) | WO1992002520A1 (ja) |
| ZA (1) | ZA916098B (ja) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993021166A1 (en) * | 1992-04-10 | 1993-10-28 | Smithkline Beecham Plc | Heterocyclic compounds and their use in the treatment of type ii-diabetes |
| US5589492A (en) * | 1992-04-10 | 1996-12-31 | Smithkline Beecham Plc | Heterocyclic compounds and their use in the treatment of Type-II diabetes |
| JPH07508747A (ja) * | 1992-07-03 | 1995-09-28 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | 医薬用複素環化合物 |
| GB9225386D0 (en) * | 1992-12-04 | 1993-01-27 | Smithkline Beecham Plc | Novel compounds |
| TW268952B (ja) * | 1993-02-26 | 1996-01-21 | Takeda Pharm Industry Co Ltd | |
| GB9311661D0 (en) * | 1993-06-05 | 1993-07-21 | Smithkline Beecham Plc | Novel compounds |
| GB9311644D0 (en) * | 1993-06-05 | 1993-07-21 | Smithkline Beecham Plc | Novel compounds |
| GB9315148D0 (en) * | 1993-07-22 | 1993-09-08 | Smithkline Beecham Plc | Novel compounds |
| US5614544A (en) * | 1993-09-14 | 1997-03-25 | Takeda Chemical Industries, Ltd. | Oxazolidinedione derivatives and their use |
| US5457109A (en) * | 1993-09-15 | 1995-10-10 | Warner-Lambert Company | Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of disease states at risk for progressing to noninsulin-dependent diabetes mellitus |
| US6046222A (en) * | 1993-09-15 | 2000-04-04 | Warner-Lambert Company | Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus |
| GB9326171D0 (en) * | 1993-12-22 | 1994-02-23 | Smithkline Beecham Plc | Novel compounds |
| US5728720A (en) * | 1993-12-27 | 1998-03-17 | Japan Tobacco Inc. | Isoxazolidinedione compounds and use thereof |
| NO303782B1 (no) * | 1994-03-23 | 1998-08-31 | Sankyo Co | Tiazolidin- og oksazolidinderivater og farmas°ytiske preparater inneholdende slike, samt deres anvendelse til fremstilling av medikamenter |
| NO305987B1 (no) * | 1994-04-11 | 1999-08-30 | Sankyo Co | Heterosykliske forbindelser med antidiabetisk aktivitet, deres anvendelse og farmasoeytisk preparat inneholdende disse |
| CZ261095A3 (en) * | 1994-10-07 | 1996-04-17 | Sankyo Co | Oxime derivatives, process of their preparation, pharmaceutical composition containing thereof and their use |
| TW403748B (en) | 1994-11-02 | 2000-09-01 | Takeda Chemical Industries Ltd | An oxazolidinedione derivative, its production and a pharmaceutical composition for lowering blood sugar and lipid in blood comprising the same |
| US5827865A (en) * | 1995-03-09 | 1998-10-27 | Smithkline Beecham P.L.C. | Heterocyclic compounds as pharmaceutical |
| US5708012A (en) * | 1995-04-28 | 1998-01-13 | Sankyo Company, Limited | Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of insulin resistant subjects with normal glucose tolerance in order to prevent or delay the onset of noninsulin-dependent mellitus |
| IL118474A (en) * | 1995-06-01 | 2001-08-08 | Sankyo Co | Benzimideol derivatives and pharmaceutical preparations containing them |
| US5798375A (en) * | 1995-07-03 | 1998-08-25 | Sankyo Company, Limited | Treatment of arteriosclerosis and xanthoma |
| CA2257284C (en) * | 1996-05-31 | 2005-10-04 | Sankyo Company Limited | Remedy for autoimmune diseases |
| DE69838789T2 (de) | 1997-03-12 | 2008-10-30 | Suzanne Cambridge de la Monte | Verfahren zur behandlung oder prävention der alzheimerischen krankheit |
| ES2221203T3 (es) | 1997-10-08 | 2004-12-16 | Sankyo Company Limited | Compuesto heterociclico fusionado sustituido. |
| HUP9902721A2 (hu) | 1997-11-25 | 1999-12-28 | The Procter & Gamble Co. | Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület |
| AU6331199A (en) * | 1998-09-30 | 2000-04-17 | Roche Diagnostics Gmbh | Oxazolidine derivatives for the treatment and prevention of metabolic bone disorders |
| BR9914438A (pt) * | 1998-10-29 | 2001-06-26 | Reddy Research Foundation | Processo aperfeiçoado para a preparação de novos agentes anti-diabéticos |
| US6191154B1 (en) | 1998-11-27 | 2001-02-20 | Case Western Reserve University | Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases |
| WO2000078312A1 (en) | 1999-06-18 | 2000-12-28 | Merck & Co., Inc. | Arylthiazolidinedione and aryloxazolidinedione derivatives |
| CA2377246A1 (en) | 1999-06-18 | 2000-12-28 | Ranjit C. Desai | Arylthiazolidinedione and aryloxazolidinedione derivatives |
| JP2001072592A (ja) | 1999-07-01 | 2001-03-21 | Kyowa Hakko Kogyo Co Ltd | テロメラーゼ阻害剤 |
| US20080108825A1 (en) * | 1999-11-08 | 2008-05-08 | Theracos, Inc. | Compounds for treatment of inflammation, diabetes and related disorders |
| US7323496B2 (en) * | 1999-11-08 | 2008-01-29 | Theracos, Inc. | Compounds for treatment of inflammation, diabetes and related disorders |
| US20080103302A1 (en) * | 2000-02-04 | 2008-05-01 | Theracos, Inc. | Compounds for treatment of inflammation, diabetes and related disorders |
| US6784199B2 (en) | 2000-09-21 | 2004-08-31 | Aryx Therapeutics | Isoxazolidine compounds useful in the treatment of diabetes, hyperlipidemia, and atherosclerosis in mammals |
| US6958355B2 (en) | 2000-04-24 | 2005-10-25 | Aryx Therapeutics, Inc. | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
| US6680387B2 (en) | 2000-04-24 | 2004-01-20 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
| US6452014B1 (en) | 2000-12-22 | 2002-09-17 | Geron Corporation | Telomerase inhibitors and methods of their use |
| ES2668310T3 (es) | 2012-11-05 | 2018-05-17 | Commissariat à l'énergie atomique et aux énergies alternatives | Combinación de un agente anticanceroso tal como un inhibidor de la tirosina cinasa y un antagonista STAT5, preferiblemente una tiazolidindiona, para eliminar las células madre de cáncer hematológico in vivo y para prevenir la recidiva de cáncer hematológico |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4367234A (en) * | 1980-07-28 | 1983-01-04 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
| US4430337A (en) * | 1982-06-23 | 1984-02-07 | Pfizer Inc. | Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity |
| ATE186724T1 (de) * | 1987-09-04 | 1999-12-15 | Beecham Group Plc | Substituierte thiazolidindionderivate |
| US5037842A (en) * | 1990-06-05 | 1991-08-06 | Pfizer Inc. | Oxa- and thiazolidinedione hypoglycemic and hypocholesterolemic agents |
-
1990
- 1990-08-06 GB GB909017218A patent/GB9017218D0/en active Pending
-
1991
- 1991-08-02 IE IE277291A patent/IE912772A1/en unknown
- 1991-08-02 ZA ZA916098A patent/ZA916098B/xx unknown
- 1991-08-05 MX MX9100529A patent/MX9100529A/es unknown
- 1991-08-05 WO PCT/GB1991/001337 patent/WO1992002520A1/en not_active Application Discontinuation
- 1991-08-05 PT PT98577A patent/PT98577A/pt not_active Application Discontinuation
- 1991-08-05 NZ NZ239265A patent/NZ239265A/en unknown
- 1991-08-05 AU AU83178/91A patent/AU646491B2/en not_active Ceased
- 1991-08-05 US US07/978,706 patent/US5391565A/en not_active Expired - Fee Related
- 1991-08-05 CA CA002093146A patent/CA2093146A1/en not_active Abandoned
- 1991-08-05 EP EP91914215A patent/EP0542816A1/en not_active Withdrawn
- 1991-08-05 KR KR1019930700345A patent/KR930701434A/ko not_active Application Discontinuation
- 1991-08-05 JP JP3513232A patent/JPH06500538A/ja active Pending
- 1991-08-06 TW TW080106151A patent/TW199156B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2093146A1 (en) | 1992-02-07 |
| JPH06500538A (ja) | 1994-01-20 |
| PT98577A (pt) | 1992-06-30 |
| GB9017218D0 (en) | 1990-09-19 |
| WO1992002520A1 (en) | 1992-02-20 |
| IE912772A1 (en) | 1992-02-12 |
| US5391565A (en) | 1995-02-21 |
| AU646491B2 (en) | 1994-02-24 |
| KR930701434A (ko) | 1993-06-11 |
| NZ239265A (en) | 1994-02-25 |
| EP0542816A1 (en) | 1993-05-26 |
| TW199156B (ja) | 1993-02-01 |
| MX9100529A (es) | 1992-04-01 |
| AU8317891A (en) | 1992-03-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0440950A3 (en) | Halogenallyl-azolyl derivatives | |
| HU912356D0 (en) | Rapacmycine derivatives | |
| ZA916098B (en) | Oxazolidinodione derivatives | |
| EP0470466A3 (en) | Halogenalkyl-azolyl derivatives | |
| GR3023621T3 (en) | 3-Hydroxy-4-aryl-5-oxo-pyrazolin derivatives | |
| ZA914484B (en) | Azolyl-propanol derivatives | |
| IL96819A0 (en) | Azaoxindole derivatives | |
| LTIP848A (en) | Hiv-inhibiting benzene-acetamide derivatives | |
| IL99576A0 (en) | Triazacyclohexane derivatives | |
| EP0438690A3 (en) | Substituted pyrazolin derivatives | |
| ZA916254B (en) | Halogenoalkyl-azolyl derivatives | |
| EP0485984A3 (en) | Diarylmethoxypiperidine derivatives | |
| ZA914204B (en) | Pyridinylpiperazine derivatives | |
| OA09670A (en) | Carbo-nucleoside derivatives | |
| EP0440949A3 (en) | Halogenallyl-azolyl derivatives | |
| ZA914675B (en) | 5-isothiazolamine derivatives | |
| IL98897A0 (en) | Carboxymethylcyclopropane derivatives | |
| EP0453883A3 (en) | 2-amino-4-trichloropyridine derivatives | |
| GB2249094B (en) | Hetero-imidazodiazepine derivatives | |
| EP0449346A3 (en) | 4-piperidinyl-ergoline derivatives | |
| EG19474A (en) | Nitroenamine derivatives | |
| EG19362A (en) | Azoaxindole derivatives | |
| IE901338L (en) | Carbamoyl-indole derivatives | |
| ZA914804B (en) | Antimigrine alkoxypyrimidine derivatives | |
| NZ240842A (en) | 4-phenoxy- and 4-pyridoxy-benzaldehyde derivatives |