ZA91574B - Use of n-myristoyl-(s)-phenylalanine for obtaining medicinal products for the treatment of diseases involving myristoylation - Google Patents

Use of n-myristoyl-(s)-phenylalanine for obtaining medicinal products for the treatment of diseases involving myristoylation

Info

Publication number
ZA91574B
ZA91574B ZA91574A ZA91574A ZA91574B ZA 91574 B ZA91574 B ZA 91574B ZA 91574 A ZA91574 A ZA 91574A ZA 91574 A ZA91574 A ZA 91574A ZA 91574 B ZA91574 B ZA 91574B
Authority
ZA
South Africa
Prior art keywords
myristoyl
phenylalanine
treatment
myristoylation
diseases involving
Prior art date
Application number
ZA91574A
Other languages
English (en)
Inventor
Michel Vincent
Vincent Michel
Georges Remond
Remond Georges
Yolande Herve
Herve Yolande
Jean-Albert Boutin
Boutin Jean-Albert
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA91574B publication Critical patent/ZA91574B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/005—Enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA91574A 1990-01-25 1991-01-25 Use of n-myristoyl-(s)-phenylalanine for obtaining medicinal products for the treatment of diseases involving myristoylation ZA91574B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9000834A FR2657259A1 (fr) 1990-01-25 1990-01-25 Utilisation de la n-myristoyl-(s)-phenylalanine pour l'obtention de medicaments destines au traitement des maladies faisant intervenir la myristoylation.

Publications (1)

Publication Number Publication Date
ZA91574B true ZA91574B (en) 1991-11-27

Family

ID=9393082

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA91574A ZA91574B (en) 1990-01-25 1991-01-25 Use of n-myristoyl-(s)-phenylalanine for obtaining medicinal products for the treatment of diseases involving myristoylation

Country Status (14)

Country Link
US (1) US5164414A (enExample)
EP (1) EP0443891B1 (enExample)
JP (1) JPH0717503B2 (enExample)
AT (1) ATE94387T1 (enExample)
AU (1) AU633395B2 (enExample)
CA (1) CA2034861A1 (enExample)
DE (1) DE69100364T2 (enExample)
DK (1) DK0443891T3 (enExample)
ES (1) ES2060310T3 (enExample)
FR (1) FR2657259A1 (enExample)
IE (1) IE65573B1 (enExample)
OA (1) OA09478A (enExample)
PT (1) PT96571A (enExample)
ZA (1) ZA91574B (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2672598A1 (fr) * 1991-02-11 1992-08-14 Adir Nouveaux inhibiteurs de n-myristoyltransferase, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5599947A (en) * 1993-01-14 1997-02-04 G. D. Searle & Co. Fatty acid analogs and prodrugs
US5859052A (en) * 1993-01-14 1999-01-12 G. D. Searle & Co. Fatty acid analogs and prodrugs
US6407125B1 (en) 1995-12-29 2002-06-18 Novactyl, Inc. Pharmacological agent and method of treatment
US6743771B2 (en) 1995-12-29 2004-06-01 Novactyl, Inc. Methods and compositions for controlling protein assembly or aggregation
US6127393A (en) 1995-12-29 2000-10-03 Novactyl, Inc. Antiproliferative, antiinfective, antiinflammatory, autologous immunization agent and method
US6579891B1 (en) 1995-12-29 2003-06-17 Novactyl, Inc. Agent and method for prevention and treatment of cancer in animals
US6441009B1 (en) 1998-08-01 2002-08-27 Novactyl, Inc. Agent and method of preventing and treating heavy metal exposure and toxicity
CA2704975A1 (en) * 1999-10-13 2001-05-31 Marco A. Chacon Therapeutic intervention to mimic the effect of caloric restriction
US6403618B1 (en) 2000-02-15 2002-06-11 Novactyl, Inc. Agent and method for controlling angiogenesis
WO2003007876A2 (en) * 2001-06-25 2003-01-30 University Of Massachusetts N-fatty acid-amino acid conjugates and therapeutic uses
DE10353806A1 (de) * 2003-11-14 2005-07-07 Bundesrepublik Deutschland, vertreten durch das Bundesministerium für Gesundheit, dieses vertreten durch das Robert-Koch-Institut, vertreten durch seinen Präsidenten Verwendung von Aminosäure- und Zucker-Amphiphilen zur Inaktivierung von lipidumhüllten Viren
US7544714B2 (en) * 2004-07-16 2009-06-09 University Of Massachusetts Lipid-amino acid conjugates and methods of use
IL172896A0 (en) * 2005-12-29 2006-06-11 Yeda Res & Dev Cxcr4 inhibition
WO2013013302A1 (en) * 2011-07-22 2013-01-31 Pacylex Pharmaceuticals Inc. Synthetic lethality and the treatment of cancer
KR102045589B1 (ko) 2012-03-30 2019-11-15 지보당 에스아 식품 향미 화합물로서의 n-아실-아미노산 유도체
EP2830441B1 (en) 2012-03-30 2019-11-13 Givaudan SA N-acyl derivatives of gamma amino-butyric acid as food flavouring compounds
EP2830438B1 (en) 2012-03-30 2019-09-04 Givaudan SA N-acyl derivatives of gamma amino-butyric acid as food flavouring compounds, powder compositions containing them
WO2013149022A1 (en) 2012-03-30 2013-10-03 Givaudan S.A. N-acyl proline derivatives as food flavouring compounds
SG11201405295WA (en) 2012-03-30 2014-11-27 Givaudan Sa N-acyl-amino acid derivatives for improvement of the flavour profile edible|compositions
CN104244734B (zh) 2012-03-30 2018-04-03 奇华顿股份有限公司 作为食品加香化合物的n‑酰化1‑氨基环烷基羧酸
SG11201405340XA (en) 2012-03-30 2014-10-30 Givaudan Sa N-acylated methionine derivatives as food flavouring compounds
SG10201703505VA (en) * 2012-10-30 2017-06-29 Pacylex Pharmaceuticals Inc Synthetic lethality and the treatment of cancer
GB201317424D0 (en) 2013-10-02 2013-11-13 Givaudan Sa Improvements in or relating to organic compounds
WO2015050534A1 (en) 2013-10-02 2015-04-09 Givaudan S.A. Organic compounds
US20160227825A1 (en) 2013-10-02 2016-08-11 Givaudan Sa Organic Compounds having Taste-Modifying Properties
WO2015048990A1 (en) 2013-10-02 2015-04-09 Givaudan Sa Organic compounds having taste-modifying properties
WO2015050535A1 (en) 2013-10-02 2015-04-09 Givaudan S.A. Organic compounds
CN105592719B (zh) * 2013-10-02 2020-03-10 奇华顿股份有限公司 有机化合物
WO2015050537A1 (en) 2013-10-02 2015-04-09 Givaudan S.A. Organic compounds
WO2015050536A1 (en) 2013-10-02 2015-04-09 Givaudan S.A. N-acylated 2-aminoisobutyric acid compounds and flavour compositions containing them
WO2017011907A1 (en) 2015-07-17 2017-01-26 Pacylex Pharmaceuticals Inc. Epigenetic silencing of nmt2

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4778878A (en) * 1986-08-07 1988-10-18 Washington University Novel inhibitor peptides I
US4778877A (en) * 1986-08-07 1988-10-18 Washington University Novel inhibitor peptides II

Also Published As

Publication number Publication date
IE910242A1 (en) 1991-07-31
PT96571A (pt) 1991-10-15
OA09478A (fr) 1992-11-15
JPH04210916A (ja) 1992-08-03
AU6998791A (en) 1991-08-01
AU633395B2 (en) 1993-01-28
US5164414A (en) 1992-11-17
CA2034861A1 (fr) 1991-07-26
EP0443891A1 (fr) 1991-08-28
DE69100364D1 (de) 1993-10-21
DK0443891T3 (da) 1993-12-27
ES2060310T3 (es) 1994-11-16
DE69100364T2 (de) 1994-04-21
IE65573B1 (en) 1995-11-01
JPH0717503B2 (ja) 1995-03-01
EP0443891B1 (fr) 1993-09-15
FR2657259A1 (fr) 1991-07-26
FR2657259B1 (enExample) 1994-08-19
ATE94387T1 (de) 1993-10-15

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