OA09478A - "Utilisation de la N-myristoyl-(S)-phénylalaine pour l'obtention de médicaments destinés au traitement des maladies faisant intervenir la myristoylation". - Google Patents

"Utilisation de la N-myristoyl-(S)-phénylalaine pour l'obtention de médicaments destinés au traitement des maladies faisant intervenir la myristoylation".

Info

Publication number
OA09478A
OA09478A OA59940A OA59940A OA09478A OA 09478 A OA09478 A OA 09478A OA 59940 A OA59940 A OA 59940A OA 59940 A OA59940 A OA 59940A OA 09478 A OA09478 A OA 09478A
Authority
OA
OAPI
Prior art keywords
myristoyl
treatment
phenylalaine
myristoylation
production
Prior art date
Application number
OA59940A
Other languages
English (en)
French (fr)
Inventor
Vincent Michel
Remond Georges
Herve Yolande
Boutin Jean-Albert
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of OA09478A publication Critical patent/OA09478A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/005—Enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
OA59940A 1990-01-25 1991-01-25 "Utilisation de la N-myristoyl-(S)-phénylalaine pour l'obtention de médicaments destinés au traitement des maladies faisant intervenir la myristoylation". OA09478A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9000834A FR2657259A1 (fr) 1990-01-25 1990-01-25 Utilisation de la n-myristoyl-(s)-phenylalanine pour l'obtention de medicaments destines au traitement des maladies faisant intervenir la myristoylation.

Publications (1)

Publication Number Publication Date
OA09478A true OA09478A (fr) 1992-11-15

Family

ID=9393082

Family Applications (1)

Application Number Title Priority Date Filing Date
OA59940A OA09478A (fr) 1990-01-25 1991-01-25 "Utilisation de la N-myristoyl-(S)-phénylalaine pour l'obtention de médicaments destinés au traitement des maladies faisant intervenir la myristoylation".

Country Status (14)

Country Link
US (1) US5164414A (enExample)
EP (1) EP0443891B1 (enExample)
JP (1) JPH0717503B2 (enExample)
AT (1) ATE94387T1 (enExample)
AU (1) AU633395B2 (enExample)
CA (1) CA2034861A1 (enExample)
DE (1) DE69100364T2 (enExample)
DK (1) DK0443891T3 (enExample)
ES (1) ES2060310T3 (enExample)
FR (1) FR2657259A1 (enExample)
IE (1) IE65573B1 (enExample)
OA (1) OA09478A (enExample)
PT (1) PT96571A (enExample)
ZA (1) ZA91574B (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2672598A1 (fr) * 1991-02-11 1992-08-14 Adir Nouveaux inhibiteurs de n-myristoyltransferase, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5599947A (en) * 1993-01-14 1997-02-04 G. D. Searle & Co. Fatty acid analogs and prodrugs
US5859052A (en) * 1993-01-14 1999-01-12 G. D. Searle & Co. Fatty acid analogs and prodrugs
US6407125B1 (en) 1995-12-29 2002-06-18 Novactyl, Inc. Pharmacological agent and method of treatment
US6579891B1 (en) 1995-12-29 2003-06-17 Novactyl, Inc. Agent and method for prevention and treatment of cancer in animals
US6127393A (en) 1995-12-29 2000-10-03 Novactyl, Inc. Antiproliferative, antiinfective, antiinflammatory, autologous immunization agent and method
US6743771B2 (en) 1995-12-29 2004-06-01 Novactyl, Inc. Methods and compositions for controlling protein assembly or aggregation
US6441009B1 (en) 1998-08-01 2002-08-27 Novactyl, Inc. Agent and method of preventing and treating heavy metal exposure and toxicity
AU784123B2 (en) * 1999-10-13 2006-02-09 Marco A. Chacon Therapeutic intervention to mimic the effect of caloric restriction
US6403618B1 (en) 2000-02-15 2002-06-11 Novactyl, Inc. Agent and method for controlling angiogenesis
WO2003007876A2 (en) * 2001-06-25 2003-01-30 University Of Massachusetts N-fatty acid-amino acid conjugates and therapeutic uses
DE10353806A1 (de) * 2003-11-14 2005-07-07 Bundesrepublik Deutschland, vertreten durch das Bundesministerium für Gesundheit, dieses vertreten durch das Robert-Koch-Institut, vertreten durch seinen Präsidenten Verwendung von Aminosäure- und Zucker-Amphiphilen zur Inaktivierung von lipidumhüllten Viren
US7544714B2 (en) * 2004-07-16 2009-06-09 University Of Massachusetts Lipid-amino acid conjugates and methods of use
IL172896A0 (en) * 2005-12-29 2006-06-11 Yeda Res & Dev Cxcr4 inhibition
KR102164964B1 (ko) * 2011-07-22 2020-10-14 페이실렉스 파마슈티컬스 인코포레이티드 암의 합성치사 및 치료
KR102045592B1 (ko) 2012-03-30 2019-11-15 지보당 에스아 식품 향미 화합물로서의 n-아실 프롤린 유도체
EP2830438B1 (en) 2012-03-30 2019-09-04 Givaudan SA N-acyl derivatives of gamma amino-butyric acid as food flavouring compounds, powder compositions containing them
BR112014023016B1 (pt) 2012-03-30 2020-10-27 Givaudan Sa composição de sabor e composição comestível
SG11201405295WA (en) 2012-03-30 2014-11-27 Givaudan Sa N-acyl-amino acid derivatives for improvement of the flavour profile edible|compositions
JP6248091B2 (ja) 2012-03-30 2017-12-13 ジボダン エス エー 食品フレーバー付与化合物としてのガンマアミノ酪酸およびベータアラニンのｎ−アシル誘導体
SG11201405340XA (en) 2012-03-30 2014-10-30 Givaudan Sa N-acylated methionine derivatives as food flavouring compounds
KR102045590B1 (ko) 2012-03-30 2019-11-15 지보당 에스아 식품 향미 화합물로서의 n-아실화된 1-아미노사이클로알킬 카복실산
AU2013337569A1 (en) * 2012-10-30 2015-05-07 Pacylex Pharmaceuticals Inc. Synthetic lethality and the treatment of cancer
EP3052472B1 (en) 2013-10-02 2019-02-27 Givaudan S.A. N-acylated 2-aminoisobutyric acid compounds and flavour compositions containing them
US10834943B2 (en) 2013-10-02 2020-11-17 Givaudan S.A. Organic compounds having taste-modifying properties
EP3057444B1 (en) 2013-10-02 2017-12-06 Givaudan SA Organic compounds having taste-modifying properties
WO2015050538A1 (en) * 2013-10-02 2015-04-09 Givaudan S.A. Organic compounds
EP3057446B1 (en) 2013-10-02 2017-12-06 Givaudan S.A. Organic compounds having taste-modifying properties
WO2015050535A1 (en) 2013-10-02 2015-04-09 Givaudan S.A. Organic compounds
CN105636459A (zh) 2013-10-02 2016-06-01 奇华顿股份有限公司 有机化合物
GB201317424D0 (en) 2013-10-02 2013-11-13 Givaudan Sa Improvements in or relating to organic compounds
PL3325662T3 (pl) 2015-07-17 2024-02-26 Pacylex Pharmaceuticals Inc. Wyciszenie epigenetyczne nmt2

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4778878A (en) * 1986-08-07 1988-10-18 Washington University Novel inhibitor peptides I
US4778877A (en) * 1986-08-07 1988-10-18 Washington University Novel inhibitor peptides II

Also Published As

Publication number Publication date
PT96571A (pt) 1991-10-15
EP0443891B1 (fr) 1993-09-15
DK0443891T3 (da) 1993-12-27
JPH04210916A (ja) 1992-08-03
ATE94387T1 (de) 1993-10-15
AU6998791A (en) 1991-08-01
CA2034861A1 (fr) 1991-07-26
ZA91574B (en) 1991-11-27
EP0443891A1 (fr) 1991-08-28
FR2657259A1 (fr) 1991-07-26
FR2657259B1 (enExample) 1994-08-19
ES2060310T3 (es) 1994-11-16
IE910242A1 (en) 1991-07-31
DE69100364T2 (de) 1994-04-21
US5164414A (en) 1992-11-17
IE65573B1 (en) 1995-11-01
AU633395B2 (en) 1993-01-28
DE69100364D1 (de) 1993-10-21
JPH0717503B2 (ja) 1995-03-01

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