ZA91574B - Use of n-myristoyl-(s)-phenylalanine for obtaining medicinal products for the treatment of diseases involving myristoylation - Google Patents
Use of n-myristoyl-(s)-phenylalanine for obtaining medicinal products for the treatment of diseases involving myristoylationInfo
- Publication number
- ZA91574B ZA91574B ZA91574A ZA91574A ZA91574B ZA 91574 B ZA91574 B ZA 91574B ZA 91574 A ZA91574 A ZA 91574A ZA 91574 A ZA91574 A ZA 91574A ZA 91574 B ZA91574 B ZA 91574B
- Authority
- ZA
- South Africa
- Prior art keywords
- myristoyl
- phenylalanine
- treatment
- myristoylation
- diseases involving
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9000834A FR2657259A1 (fr) | 1990-01-25 | 1990-01-25 | Utilisation de la n-myristoyl-(s)-phenylalanine pour l'obtention de medicaments destines au traitement des maladies faisant intervenir la myristoylation. |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA91574B true ZA91574B (en) | 1991-11-27 |
Family
ID=9393082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA91574A ZA91574B (en) | 1990-01-25 | 1991-01-25 | Use of n-myristoyl-(s)-phenylalanine for obtaining medicinal products for the treatment of diseases involving myristoylation |
Country Status (14)
Country | Link |
---|---|
US (1) | US5164414A (xx) |
EP (1) | EP0443891B1 (xx) |
JP (1) | JPH0717503B2 (xx) |
AT (1) | ATE94387T1 (xx) |
AU (1) | AU633395B2 (xx) |
CA (1) | CA2034861A1 (xx) |
DE (1) | DE69100364T2 (xx) |
DK (1) | DK0443891T3 (xx) |
ES (1) | ES2060310T3 (xx) |
FR (1) | FR2657259A1 (xx) |
IE (1) | IE65573B1 (xx) |
OA (1) | OA09478A (xx) |
PT (1) | PT96571A (xx) |
ZA (1) | ZA91574B (xx) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2672598A1 (fr) * | 1991-02-11 | 1992-08-14 | Adir | Nouveaux inhibiteurs de n-myristoyltransferase, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
US5859052A (en) * | 1993-01-14 | 1999-01-12 | G. D. Searle & Co. | Fatty acid analogs and prodrugs |
US5599947A (en) * | 1993-01-14 | 1997-02-04 | G. D. Searle & Co. | Fatty acid analogs and prodrugs |
US6127393A (en) * | 1995-12-29 | 2000-10-03 | Novactyl, Inc. | Antiproliferative, antiinfective, antiinflammatory, autologous immunization agent and method |
US6407125B1 (en) | 1995-12-29 | 2002-06-18 | Novactyl, Inc. | Pharmacological agent and method of treatment |
US6579891B1 (en) | 1995-12-29 | 2003-06-17 | Novactyl, Inc. | Agent and method for prevention and treatment of cancer in animals |
US6743771B2 (en) | 1995-12-29 | 2004-06-01 | Novactyl, Inc. | Methods and compositions for controlling protein assembly or aggregation |
US6441009B1 (en) | 1998-08-01 | 2002-08-27 | Novactyl, Inc. | Agent and method of preventing and treating heavy metal exposure and toxicity |
EP1220669A4 (en) * | 1999-10-13 | 2004-12-08 | Marco A Chacon | THERAPEUTIC MEASURE TO IMPROVE THE EFFECT OF A CALORY RESTRICTION |
US6403618B1 (en) | 2000-02-15 | 2002-06-11 | Novactyl, Inc. | Agent and method for controlling angiogenesis |
WO2003007876A2 (en) * | 2001-06-25 | 2003-01-30 | University Of Massachusetts | N-fatty acid-amino acid conjugates and therapeutic uses |
DE10353806A1 (de) * | 2003-11-14 | 2005-07-07 | Bundesrepublik Deutschland, vertreten durch das Bundesministerium für Gesundheit, dieses vertreten durch das Robert-Koch-Institut, vertreten durch seinen Präsidenten | Verwendung von Aminosäure- und Zucker-Amphiphilen zur Inaktivierung von lipidumhüllten Viren |
US7544714B2 (en) * | 2004-07-16 | 2009-06-09 | University Of Massachusetts | Lipid-amino acid conjugates and methods of use |
IL172896A0 (en) * | 2005-12-29 | 2006-06-11 | Yeda Res & Dev | Cxcr4 inhibition |
WO2013013302A1 (en) * | 2011-07-22 | 2013-01-31 | Pacylex Pharmaceuticals Inc. | Synthetic lethality and the treatment of cancer |
JP6209588B2 (ja) | 2012-03-30 | 2017-10-04 | ジボダン エス エー | 食品フレーバー付与化合物としてのn−アシルプロリン誘導体 |
US10582715B2 (en) | 2012-03-30 | 2020-03-10 | Givaudan Sa | Powder flavour composition |
CN104244734B (zh) | 2012-03-30 | 2018-04-03 | 奇华顿股份有限公司 | 作为食品加香化合物的n‑酰化1‑氨基环烷基羧酸 |
JP6250029B2 (ja) | 2012-03-30 | 2017-12-20 | ジボダン エス エー | 食品フレーバー付与化合物としてのn−アシル−アミノ酸誘導体 |
CN104219965B (zh) | 2012-03-30 | 2018-10-12 | 奇华顿股份有限公司 | 作为食品加香化合物的γ氨基-丁酸和β丙氨酸的N-酰基衍生物 |
CN104254253B (zh) | 2012-03-30 | 2017-12-29 | 奇华顿股份有限公司 | 作为食品加香化合物的n‑酰化甲硫氨酸衍生物 |
JP6224072B2 (ja) | 2012-03-30 | 2017-11-01 | ジボダン エス エー | フレーバープロフィール食用組成物の改良のためのn−アシル−アミノ酸誘導体 |
CN110974967B (zh) * | 2012-10-30 | 2023-11-07 | 厄尔莱克斯制药公司 | 合成致死与癌症的治疗 |
WO2015048991A1 (en) | 2013-10-02 | 2015-04-09 | Givaudan Sa | Organic compounds having taste-modifying properties |
US10674755B2 (en) | 2013-10-02 | 2020-06-09 | Givaudan S.A. | Organic Compounds |
GB201317424D0 (en) | 2013-10-02 | 2013-11-13 | Givaudan Sa | Improvements in or relating to organic compounds |
WO2015050535A1 (en) | 2013-10-02 | 2015-04-09 | Givaudan S.A. | Organic compounds |
CN105636934B (zh) | 2013-10-02 | 2019-03-29 | 奇华顿股份有限公司 | N-酰化的2-氨基异丁酸化合物和包含它们的香味组合物 |
CN105636457B (zh) | 2013-10-02 | 2020-03-10 | 奇华顿股份有限公司 | 具有味道改进特性的有机化合物 |
US10834950B2 (en) | 2013-10-02 | 2020-11-17 | Givaudan S.A. | Organic compounds |
WO2015050537A1 (en) | 2013-10-02 | 2015-04-09 | Givaudan S.A. | Organic compounds |
ES2964607T3 (es) | 2015-07-17 | 2024-04-08 | Pacylex Pharmaceuticals Inc | Silenciamiento epigenético de NMT2 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4778878A (en) * | 1986-08-07 | 1988-10-18 | Washington University | Novel inhibitor peptides I |
US4778877A (en) * | 1986-08-07 | 1988-10-18 | Washington University | Novel inhibitor peptides II |
-
1990
- 1990-01-25 FR FR9000834A patent/FR2657259A1/fr active Granted
-
1991
- 1991-01-24 US US07/645,124 patent/US5164414A/en not_active Expired - Fee Related
- 1991-01-24 JP JP3007188A patent/JPH0717503B2/ja not_active Expired - Lifetime
- 1991-01-24 IE IE24291A patent/IE65573B1/en not_active IP Right Cessation
- 1991-01-24 CA CA002034861A patent/CA2034861A1/fr not_active Abandoned
- 1991-01-24 PT PT96571A patent/PT96571A/pt not_active Application Discontinuation
- 1991-01-25 ZA ZA91574A patent/ZA91574B/xx unknown
- 1991-01-25 AU AU69987/91A patent/AU633395B2/en not_active Ceased
- 1991-01-25 DE DE91400163T patent/DE69100364T2/de not_active Expired - Fee Related
- 1991-01-25 ES ES91400163T patent/ES2060310T3/es not_active Expired - Lifetime
- 1991-01-25 EP EP91400163A patent/EP0443891B1/fr not_active Expired - Lifetime
- 1991-01-25 AT AT91400163T patent/ATE94387T1/de active
- 1991-01-25 OA OA59940A patent/OA09478A/xx unknown
- 1991-01-25 DK DK91400163.1T patent/DK0443891T3/da active
Also Published As
Publication number | Publication date |
---|---|
DE69100364D1 (de) | 1993-10-21 |
FR2657259B1 (xx) | 1994-08-19 |
IE65573B1 (en) | 1995-11-01 |
US5164414A (en) | 1992-11-17 |
OA09478A (fr) | 1992-11-15 |
DK0443891T3 (da) | 1993-12-27 |
DE69100364T2 (de) | 1994-04-21 |
IE910242A1 (en) | 1991-07-31 |
AU6998791A (en) | 1991-08-01 |
JPH0717503B2 (ja) | 1995-03-01 |
ATE94387T1 (de) | 1993-10-15 |
JPH04210916A (ja) | 1992-08-03 |
ES2060310T3 (es) | 1994-11-16 |
FR2657259A1 (fr) | 1991-07-26 |
PT96571A (pt) | 1991-10-15 |
EP0443891A1 (fr) | 1991-08-28 |
AU633395B2 (en) | 1993-01-28 |
CA2034861A1 (fr) | 1991-07-26 |
EP0443891B1 (fr) | 1993-09-15 |
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