ZA913393B - 9-substituted compounds of 3alpha,11alpha-epoxy-3,4,5,5alpha,6,7,8,8a,9,11,11a-undecahydro-3beta,6alpha,9-trimethylfurano(3,4-j)(1,2)-benzodioxepin,process for their preparation and their use as antiprotozoal and antiviral agents - Google Patents

9-substituted compounds of 3alpha,11alpha-epoxy-3,4,5,5alpha,6,7,8,8a,9,11,11a-undecahydro-3beta,6alpha,9-trimethylfurano(3,4-j)(1,2)-benzodioxepin,process for their preparation and their use as antiprotozoal and antiviral agents

Info

Publication number
ZA913393B
ZA913393B ZA913393A ZA913393A ZA913393B ZA 913393 B ZA913393 B ZA 913393B ZA 913393 A ZA913393 A ZA 913393A ZA 913393 A ZA913393 A ZA 913393A ZA 913393 B ZA913393 B ZA 913393B
Authority
ZA
South Africa
Prior art keywords
trimethylfurano
undecahydro
11alpha
6alpha
3alpha
Prior art date
Application number
ZA913393A
Other languages
English (en)
Inventor
Bindumadhavan Venugopalan
Venugopalan Bindumadhavan
Chintamani Prabhakar Bapat
Prabhakar Bapat Chintamani
Pravin Jayant Kornik
Jayant Kornik Pravin
Bansi Lal
Lal Bansi
Dipak Kumar Chatterjee
Kumar Chatterjee Dipak
Subramani Nalrajan Iyer
Nalrajan Iyer Subramani
Juergen Blumbach
Blumbach Juergen
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA913393B publication Critical patent/ZA913393B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA913393A 1990-05-07 1991-05-06 9-substituted compounds of 3alpha,11alpha-epoxy-3,4,5,5alpha,6,7,8,8a,9,11,11a-undecahydro-3beta,6alpha,9-trimethylfurano(3,4-j)(1,2)-benzodioxepin,process for their preparation and their use as antiprotozoal and antiviral agents ZA913393B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90108580 1990-05-07

Publications (1)

Publication Number Publication Date
ZA913393B true ZA913393B (en) 1992-02-26

Family

ID=8203955

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA913393A ZA913393B (en) 1990-05-07 1991-05-06 9-substituted compounds of 3alpha,11alpha-epoxy-3,4,5,5alpha,6,7,8,8a,9,11,11a-undecahydro-3beta,6alpha,9-trimethylfurano(3,4-j)(1,2)-benzodioxepin,process for their preparation and their use as antiprotozoal and antiviral agents

Country Status (11)

Country Link
US (1) US5246930A (sh)
EP (1) EP0456149A1 (sh)
JP (1) JPH04225983A (sh)
KR (1) KR920005722A (sh)
AU (1) AU639095B2 (sh)
BR (1) BR9101822A (sh)
IE (1) IE911529A1 (sh)
IL (1) IL98071A0 (sh)
PT (1) PT97577A (sh)
TW (1) TW198722B (sh)
ZA (1) ZA913393B (sh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993008195A1 (en) * 1991-10-14 1993-04-29 The University Of Sydney Cyclic peroxyacetal compounds
CA2337119A1 (en) 1998-07-14 2000-01-27 Richard K. Haynes Antiparasitic artemisinin derivatives (endoperoxides)
IN191696B (sh) * 1999-02-12 2003-12-20 Council Scient Ind Res
US7842719B2 (en) 2002-10-31 2010-11-30 Kemin Foods, L.C. Use of endoperoxides for the treatment of infections caused by flaviviridae, including hepatitis C, bovine viral diarrhea and classical swine fever virus
US20110206636A1 (en) * 2003-09-16 2011-08-25 Kemin Foods, LLC Use of Endoperoxides for the Treatment of Infections Caused by Flaviviridae, Including Hepatitis C, Bovine Viral Diarrhea and Classical Swine Fever Virus
CN1311832C (zh) * 2005-01-12 2007-04-25 四川科伦药业股份有限公司 溴代二氢青蒿素的医药用途
CN103159777A (zh) * 2013-03-05 2013-06-19 华东师范大学 一种卤代青蒿素衍生物的合成方法
CN104086560A (zh) * 2014-07-03 2014-10-08 唐心建 卤代青蒿素母核、卤代青蒿素衍生物、卤代双氢青蒿素、卤代脱羰青蒿素以及医药用途
CN107011356A (zh) * 2017-06-08 2017-08-04 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 一种脱水双氢青蒿素的合成方法
CN110981887B (zh) * 2019-09-12 2022-05-17 延边大学 一类二氢青蒿素类化合物及其制备方法和医用用途
KR102266875B1 (ko) * 2019-12-12 2021-06-18 대한민국 감자 바이러스 y 방제용 화합물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0346356A1 (en) * 1986-12-18 1989-12-20 Sri International Synthesis process and oxygen-containing heterocyclic products thereof
US4963683A (en) * 1986-12-18 1990-10-16 Sri International Process for preparing polyoxa tetracyclic compounds
GB8804372D0 (en) * 1988-02-25 1988-03-23 World Health Org Synthesis of dihydroqinghaosu derivatives
EP0362730A1 (en) * 1988-10-04 1990-04-11 Hoechst Aktiengesellschaft Artemisinin derivatives, processes for their preparation and their use as antiprotozoal agents

Also Published As

Publication number Publication date
BR9101822A (pt) 1991-12-17
EP0456149A1 (en) 1991-11-13
IE911529A1 (en) 1991-11-20
IL98071A0 (en) 1992-06-21
AU7618591A (en) 1991-11-07
KR920005722A (ko) 1992-04-03
AU639095B2 (en) 1993-07-15
TW198722B (sh) 1993-01-21
US5246930A (en) 1993-09-21
PT97577A (pt) 1992-01-31
JPH04225983A (ja) 1992-08-14

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