ZA912588B - Novel alpha-mannosidase and fucosidase inhibitors - Google Patents
Novel alpha-mannosidase and fucosidase inhibitorsInfo
- Publication number
- ZA912588B ZA912588B ZA912588A ZA912588A ZA912588B ZA 912588 B ZA912588 B ZA 912588B ZA 912588 A ZA912588 A ZA 912588A ZA 912588 A ZA912588 A ZA 912588A ZA 912588 B ZA912588 B ZA 912588B
- Authority
- ZA
- South Africa
- Prior art keywords
- alpha
- mannosidase
- novel alpha
- fucosidase inhibitors
- fucosidase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/44—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50887590A | 1990-04-12 | 1990-04-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA912588B true ZA912588B (en) | 1992-01-29 |
Family
ID=24024437
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA912588A ZA912588B (en) | 1990-04-12 | 1991-04-08 | Novel alpha-mannosidase and fucosidase inhibitors |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0451834B1 (de) |
JP (1) | JP2955057B2 (de) |
KR (1) | KR100197382B1 (de) |
CN (1) | CN1033638C (de) |
AT (1) | ATE140692T1 (de) |
AU (1) | AU646855B2 (de) |
CA (1) | CA2040058C (de) |
DE (1) | DE69121000T2 (de) |
DK (1) | DK0451834T3 (de) |
ES (1) | ES2092520T3 (de) |
FI (1) | FI109200B (de) |
GR (1) | GR3020934T3 (de) |
HU (1) | HU213396B (de) |
IE (1) | IE75195B1 (de) |
IL (1) | IL97814A (de) |
NO (1) | NO175856C (de) |
NZ (1) | NZ237734A (de) |
PT (1) | PT97339B (de) |
ZA (1) | ZA912588B (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5773239A (en) * | 1993-10-19 | 1998-06-30 | Mount Sinai Hospital Corporation. | Mannosidase inhibitors, process for their preparation and their use as therapeutic agents |
US5650413A (en) * | 1995-06-07 | 1997-07-22 | Glycodesign Inc. | Derivatives of swainsonine, processes for their preparation and their use as therapeutic agents |
JP2001501213A (ja) * | 1996-10-01 | 2001-01-30 | グリコデザイン・インコーポレーテツド | スワインソニンの新規な3,5,および/または6置換された同族体、それらの製造方法および治療剤としてのそれらの使用 |
CA2286766A1 (en) | 1997-04-15 | 1998-10-22 | Glycodesign Inc. | Alkaloid halide salts of swainsonine and methods of use |
WO1999021858A1 (en) * | 1997-10-24 | 1999-05-06 | Glycodesign Inc. | Synthesis of swainsonine salts |
JP6170675B2 (ja) * | 2010-01-28 | 2017-07-26 | ラプトール ファーマシューティカルズ インコーポレイテッド | 受容体関連タンパク質(rap)ペプチド−フコシダーゼ阻害薬複合体による肝障害処置のための方法 |
CN101870992A (zh) * | 2010-06-21 | 2010-10-27 | 天津科技大学 | 利用基因工程菌耦合发酵合成gdp-岩藻糖的方法 |
CN102286608B (zh) * | 2011-06-08 | 2014-06-25 | 郑州安图生物工程股份有限公司 | 衣原体诊断方法和试剂盒 |
-
1991
- 1991-04-08 ZA ZA912588A patent/ZA912588B/xx unknown
- 1991-04-08 CA CA002040058A patent/CA2040058C/en not_active Expired - Fee Related
- 1991-04-08 AU AU74164/91A patent/AU646855B2/en not_active Ceased
- 1991-04-08 NZ NZ237734A patent/NZ237734A/xx unknown
- 1991-04-10 IL IL9781491A patent/IL97814A/en not_active IP Right Cessation
- 1991-04-11 HU HU911196A patent/HU213396B/hu not_active IP Right Cessation
- 1991-04-11 KR KR1019910005783A patent/KR100197382B1/ko not_active IP Right Cessation
- 1991-04-11 DK DK91105766.9T patent/DK0451834T3/da active
- 1991-04-11 CN CN91102294A patent/CN1033638C/zh not_active Expired - Fee Related
- 1991-04-11 FI FI911751A patent/FI109200B/fi not_active IP Right Cessation
- 1991-04-11 AT AT91105766T patent/ATE140692T1/de not_active IP Right Cessation
- 1991-04-11 IE IE122991A patent/IE75195B1/en not_active IP Right Cessation
- 1991-04-11 PT PT97339A patent/PT97339B/pt active IP Right Grant
- 1991-04-11 EP EP91105766A patent/EP0451834B1/de not_active Expired - Lifetime
- 1991-04-11 DE DE69121000T patent/DE69121000T2/de not_active Expired - Fee Related
- 1991-04-11 NO NO911419A patent/NO175856C/no unknown
- 1991-04-11 ES ES91105766T patent/ES2092520T3/es not_active Expired - Lifetime
- 1991-04-12 JP JP3106388A patent/JP2955057B2/ja not_active Expired - Fee Related
-
1996
- 1996-09-03 GR GR960402291T patent/GR3020934T3/el unknown
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