ZA909852B - Diazine derivatives - Google Patents

Diazine derivatives

Info

Publication number
ZA909852B
ZA909852B ZA909852A ZA909852A ZA909852B ZA 909852 B ZA909852 B ZA 909852B ZA 909852 A ZA909852 A ZA 909852A ZA 909852 A ZA909852 A ZA 909852A ZA 909852 B ZA909852 B ZA 909852B
Authority
ZA
South Africa
Prior art keywords
alkyl
phenyl
formula
substituents
hydrogen
Prior art date
Application number
ZA909852A
Other languages
English (en)
Inventor
Rodney Brian Hargreaves
Brian Hargreaves Rodney
Bernard Joseph Mcloughlin
Joseph Mcloughlin Bernard
Stuart Dennett Mills
Dennett Mills Stuart
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of ZA909852B publication Critical patent/ZA909852B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Organic Insulating Materials (AREA)
  • Vibration Prevention Devices (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA909852A 1989-12-22 1990-12-07 Diazine derivatives ZA909852B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898929022A GB8929022D0 (en) 1989-12-22 1989-12-22 Diazine derivatives

Publications (1)

Publication Number Publication Date
ZA909852B true ZA909852B (en) 1991-10-30

Family

ID=10668392

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA909852A ZA909852B (en) 1989-12-22 1990-12-07 Diazine derivatives

Country Status (21)

Country Link
US (1) US5252567A (it)
EP (1) EP0434341B1 (it)
JP (1) JPH03291277A (it)
KR (1) KR910011838A (it)
AT (1) ATE122672T1 (it)
AU (1) AU641960B2 (it)
CA (1) CA2032743A1 (it)
DE (1) DE69019489T2 (it)
DK (1) DK0434341T3 (it)
ES (1) ES2072993T3 (it)
FI (1) FI906306A (it)
GB (2) GB8929022D0 (it)
HU (1) HU207511B (it)
IE (1) IE904391A1 (it)
IL (1) IL96609A0 (it)
NO (1) NO905378L (it)
NZ (1) NZ236417A (it)
PT (1) PT96315B (it)
TW (1) TW215088B (it)
ZA (1) ZA909852B (it)
ZW (1) ZW19290A1 (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9022644D0 (en) * 1990-10-18 1990-11-28 Ici Plc Heterocyclic compounds
CA2534975A1 (en) * 2003-08-07 2005-02-17 Pharmacia & Upjohn Company Llc Anthelmintic and insecticide pyrimidine derivatives
US7741976B2 (en) * 2005-12-16 2010-06-22 Hunt Power, L.P. Server and method for processing meter data into a common format
RU2719422C2 (ru) 2014-08-04 2020-04-17 Нуэволюшон А/С Необязательно конденсированные гетероциклил-замещенные производные пиримидина, пригодные для лечения воспалительных, метаболических, онкологических и аутоиммунных заболеваний
WO2021124277A1 (en) 2019-12-20 2021-06-24 Nuevolution A/S Compounds active towards nuclear receptors
WO2021198956A1 (en) 2020-03-31 2021-10-07 Nuevolution A/S Compounds active towards nuclear receptors
US11780843B2 (en) 2020-03-31 2023-10-10 Nuevolution A/S Compounds active towards nuclear receptors

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB815833A (en) * 1956-09-26 1959-07-01 Boots Pure Drug Co Ltd Phenanthridine compounds
BE492034A (it) * 1948-11-05
DE1445740A1 (de) * 1963-09-04 1968-11-28 Bayer Ag Verfahren zur Herstellung von Bispyrimidinium-Verbindungen
US4339453A (en) * 1979-07-23 1982-07-13 Merck & Co., Inc. Antimicrobial aminopyrimidinium salts
US4287338A (en) * 1980-03-10 1981-09-01 The Upjohn Company Sulfooxy-pyrimidinium, -pyridinium, and -triazinium hydroxide inner salts
FR2524467A1 (fr) * 1982-03-30 1983-10-07 Adir Polymethylene-imines disubstituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
US4503050A (en) * 1983-06-02 1985-03-05 Riker Laboratories, Inc. Substituted imidazo[1,2-c]pyrimidines
US4725600A (en) * 1984-07-13 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent
WO1987001706A2 (en) * 1985-09-12 1987-03-26 The Upjohn Company C20 through c26 amino steroids
DE3703633A1 (de) * 1986-02-14 1987-08-20 Sandoz Ag Purin-derivate, ihre herstellung und sie enthaltende arzneimittel
US4729995A (en) * 1986-04-21 1988-03-08 Toyo Boseki Kabushiki Kaisha Pyrimidine 2,4-dioxamate compounds and pharmaceutical compositions
DE3629563A1 (de) * 1986-08-02 1988-02-04 Mildenberger & Willing Verpack Tragbarer verpackungsbeutel aus kunststoffolie und verfahren zu dessen herstellung
DE3639563A1 (de) * 1986-11-20 1988-06-01 Basf Ag N-arylsulfonyl-n'-pyrimidyl(triazinyl) -harnstoffe
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
FI906306A0 (fi) 1990-12-20
ATE122672T1 (de) 1995-06-15
PT96315A (pt) 1991-09-30
GB8929022D0 (en) 1990-02-28
GB9025810D0 (en) 1991-01-09
EP0434341B1 (en) 1995-05-17
EP0434341A1 (en) 1991-06-26
NO905378D0 (no) 1990-12-12
PT96315B (pt) 1998-06-30
HUT56087A (en) 1991-07-29
NO905378L (no) 1991-06-24
DE69019489T2 (de) 1995-09-21
IE904391A1 (en) 1991-07-03
HU207511B (en) 1993-04-28
CA2032743A1 (en) 1991-06-23
IL96609A0 (en) 1991-09-16
ZW19290A1 (en) 1991-09-18
DK0434341T3 (da) 1995-10-09
AU641960B2 (en) 1993-10-07
JPH03291277A (ja) 1991-12-20
US5252567A (en) 1993-10-12
HU908115D0 (en) 1991-06-28
NZ236417A (en) 1994-04-27
AU6791490A (en) 1991-06-27
DE69019489D1 (de) 1995-06-22
ES2072993T3 (es) 1995-08-01
FI906306A (fi) 1991-06-23
KR910011838A (ko) 1991-08-07
TW215088B (it) 1993-10-21

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