ZA906302B - Novel 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives,pharmaceutical compositions containing them and process for preparing same - Google Patents

Novel 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives,pharmaceutical compositions containing them and process for preparing same

Info

Publication number
ZA906302B
ZA906302B ZA906302A ZA906302A ZA906302B ZA 906302 B ZA906302 B ZA 906302B ZA 906302 A ZA906302 A ZA 906302A ZA 906302 A ZA906302 A ZA 906302A ZA 906302 B ZA906302 B ZA 906302B
Authority
ZA
South Africa
Prior art keywords
group
alkyl
halogen atoms
oxa
oxo
Prior art date
Application number
ZA906302A
Other languages
English (en)
Inventor
Edit Toth
Toth Edit
Jozsef Toerley
Toerley Jozsef
Laszlo Szporny
Szporny Laszlo
Bela Kiss
Kiss Bela
Egon Karpati
Karpati Egon
Eva Palosi
Palosi Eva
Dora Groo
Groo Dora
Istvan Laszlovszky
Laszlovszky Istvan
Zsolt Szombathelyi
Szombathelyi Zsolt
Adam Sarkadi
Sarkadi Adam
Aniko Gere
Gere Aniko
Katalin Csomor
Csomor Katalin
Mihaly Bodo
Bodo Mihaly
Judit Laszy
Laszy Judit
Zsolt Szentimay
Szentimay Zsolt
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ZA906302B publication Critical patent/ZA906302B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
ZA906302A 1989-08-10 1990-08-09 Novel 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives,pharmaceutical compositions containing them and process for preparing same ZA906302B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU894095A HU204530B (en) 1989-08-10 1989-08-10 Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
SG96294A SG96294G (en) 1989-08-10 1994-07-16 1-oxa-2-oxo-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
ZA906302B true ZA906302B (en) 1991-06-26

Family

ID=26317733

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA906302A ZA906302B (en) 1989-08-10 1990-08-09 Novel 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives,pharmaceutical compositions containing them and process for preparing same

Country Status (23)

Country Link
US (1) US5118687A (fr)
EP (1) EP0414421B1 (fr)
JP (1) JPH0749431B2 (fr)
KR (1) KR940006635B1 (fr)
AT (1) ATE103920T1 (fr)
AU (1) AU622039B2 (fr)
BG (1) BG60436B2 (fr)
DD (1) DD299429A5 (fr)
DE (1) DE69007904T2 (fr)
DK (1) DK0414421T3 (fr)
ES (1) ES2052180T3 (fr)
FI (1) FI93455C (fr)
HK (1) HK145994A (fr)
HR (1) HRP920778A2 (fr)
HU (2) HU204530B (fr)
IE (1) IE64911B1 (fr)
IL (1) IL95320A (fr)
NO (1) NO177962C (fr)
NZ (1) NZ234848A (fr)
PL (3) PL163593B1 (fr)
SG (1) SG96294G (fr)
SI (1) SI9011538A (fr)
ZA (1) ZA906302B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU150489A (sh) * 1989-08-10 1992-12-21 W.L. Gore & Co. Gmbh. Uređaj za ispitivanje odevnih predmeta na nepromočivost
EP2286847A1 (fr) * 1999-10-15 2011-02-23 Genetics Institute, LLC Formulations à base d'acide hyaluronique aux fins de l'administration de proteines osteogenes
KR20020091462A (ko) * 2001-05-30 2002-12-06 삼성광주전자 주식회사 원료 굳음 방지기능을 갖는 자동판매기 및 그 제어방법
GB201416346D0 (en) * 2014-09-16 2014-10-29 Shire Internat Gmbh Spirocyclic derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR96352E (fr) * 1967-12-29 1972-06-16 Science Union & Cie Nouveaux dérives du spiro (4,5) decane et leur procédé de préparation.
BE790675A (fr) * 1971-10-29 1973-04-27 Science Union & Cie Nouveaux derives de l'oxa-1 diaza-3,8 spiro (4,5) decane
EP0189370A3 (fr) * 1985-01-16 1988-01-27 Sandoz Ag Spiro-dioxolanes, -dithiolanes et -oxothiolanes
KR940003491B1 (ko) * 1989-08-10 1994-04-23 리히터 게데온 베기에스제티 기아르 알.티 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물
HU204529B (en) * 1989-08-10 1992-01-28 Richter Gedeon Vegyeszet Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0414421B1 (fr) 1994-04-06
DE69007904D1 (de) 1994-05-11
DK0414421T3 (da) 1994-05-16
DE69007904T2 (de) 1994-07-21
JPH0377884A (ja) 1991-04-03
PL286440A1 (en) 1992-01-27
IL95320A0 (en) 1991-06-30
ATE103920T1 (de) 1994-04-15
JPH0749431B2 (ja) 1995-05-31
IE902884A1 (en) 1991-02-27
HK145994A (en) 1994-12-30
SI9011538A (sl) 1998-08-31
BG60436B2 (bg) 1995-03-31
NO177962B (no) 1995-09-18
ES2052180T3 (es) 1994-07-01
KR940006635B1 (ko) 1994-07-23
AU6080790A (en) 1991-02-14
FI93455B (fi) 1994-12-30
FI903972A0 (fi) 1990-08-10
KR910004632A (ko) 1991-03-29
SG96294G (en) 1994-10-28
EP0414421A3 (en) 1991-07-24
IE64911B1 (en) 1995-09-20
PL163370B1 (pl) 1994-03-31
IL95320A (en) 1994-01-25
FI93455C (fi) 1995-04-10
NO903512L (no) 1991-02-11
NZ234848A (en) 1992-03-26
DD299429A5 (de) 1992-04-16
HRP920778A2 (en) 1998-02-28
HUT55786A (en) 1991-06-28
HU204530B (en) 1992-01-28
NO177962C (no) 1995-12-27
NO903512D0 (no) 1990-08-09
US5118687A (en) 1992-06-02
HU210072A9 (en) 1995-02-28
PL163593B1 (en) 1994-04-29
EP0414421A2 (fr) 1991-02-27
PL163431B1 (pl) 1994-03-31
PL291701A1 (en) 1992-05-04
PL291702A1 (en) 1992-05-04
AU622039B2 (en) 1992-03-26

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