ZA905306B - Topically administrable pharmaceutical preparations - Google Patents

Topically administrable pharmaceutical preparations

Info

Publication number
ZA905306B
ZA905306B ZA905306A ZA905306A ZA905306B ZA 905306 B ZA905306 B ZA 905306B ZA 905306 A ZA905306 A ZA 905306A ZA 905306 A ZA905306 A ZA 905306A ZA 905306 B ZA905306 B ZA 905306B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical preparations
topically administrable
administrable pharmaceutical
topically
preparations
Prior art date
Application number
ZA905306A
Other languages
English (en)
Inventor
Pier Giorgio Ferrini
Giorgio Ferrini Pier
Peter Heinrich Stahl
Heinrich Stahl Peter
Carlo Voellmy
Voellmy Carlo
Jonathan Green
Green Jonathan
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of ZA905306B publication Critical patent/ZA905306B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
ZA905306A 1989-07-07 1990-07-06 Topically administrable pharmaceutical preparations ZA905306B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH253289 1989-07-07

Publications (1)

Publication Number Publication Date
ZA905306B true ZA905306B (en) 1991-02-27

Family

ID=4235919

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA905306A ZA905306B (en) 1989-07-07 1990-07-06 Topically administrable pharmaceutical preparations

Country Status (15)

Country Link
US (1) US5133972A (fr)
EP (1) EP0407344A3 (fr)
JP (1) JPH0344328A (fr)
KR (1) KR910002432A (fr)
AU (1) AU633598B2 (fr)
CA (1) CA2020557A1 (fr)
DD (1) DD296418A5 (fr)
FI (1) FI903382A0 (fr)
HU (1) HUT54502A (fr)
IE (1) IE902481A1 (fr)
IL (1) IL94926A (fr)
MX (1) MX21452A (fr)
NZ (1) NZ234377A (fr)
PT (1) PT94611B (fr)
ZA (1) ZA905306B (fr)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0522576A3 (en) * 1991-07-12 1993-07-14 Hoechst Aktiengesellschaft Aminoethane-1,1-bisphosphonic acids and aminoethane-1,1-alkylphospinic/phosphonic acids, process of their preparation and their use
US5328696A (en) * 1991-07-22 1994-07-12 Dow Corning Corporation Devices using silicone pressure sensitive adhesives containing organic wax
DE69212254T2 (de) * 1991-08-14 1996-12-19 Kao Corp Haarpflegemittel
ES2114946T3 (es) * 1991-09-05 1998-06-16 Toray Industries Derivado de acido metanodifosfonico, su produccion y uso medicinal.
US6096342A (en) * 1997-03-12 2000-08-01 The Procter & Gamble Company Dosage forms of risedronate
CA2122479C (fr) * 1991-11-22 1998-08-25 Richard John Dansereau Compositions de risedronate a liberation retardee
TW237386B (fr) * 1992-04-15 1995-01-01 Ciba Geigy
US5283057A (en) * 1992-04-24 1994-02-01 The Procter & Gamble Company Risedronate in oral compositions
GB9215433D0 (en) * 1992-07-21 1992-09-02 Cmb Foodcan Plc Apparatus for stripping a drawn article from a punch
AU670337B2 (en) 1992-11-30 1996-07-11 Novartis Ag Use of certain methanebisphosphonic acid derivatives in fracture healing
DE69330388T2 (de) * 1992-12-31 2002-01-03 Sunkyong Ind Ltd Pharmazeutische zusammensetzungen mit verbesserter perkutaner absorption für piroxicam
DE4308649C2 (de) * 1993-03-18 1995-11-16 Lohmann Gmbh & Co Kg Medizinisches Pflastermaterial sowie Verfahren zu seiner Herstellung und dessen Verwendung
US5728650A (en) * 1993-10-07 1998-03-17 Zeneca Limited Herbicidal aza bisphosphonic acids and compositions containing the same
CZ288725B6 (cs) * 1994-11-09 2001-08-15 The Procter & Gamble Company Čisticí prostředek napuštěný emulzí vody v lipidu a způsob jeho výroby
US5948540A (en) * 1995-04-27 1999-09-07 The Procter & Gamble Company Carrier substrate treated with high internal phase inverse emulsions made with an organopolysiloxane-polyoxyalkylene emulsifier
HUP9801443A3 (en) * 1995-04-27 2001-11-28 Procter & Gamble Carrier substrate treated with high internal water phase inverse emulsion made with an organopolysiloxane-polyoxyalkylene emulsifier
US5763332A (en) * 1996-04-30 1998-06-09 The Procter & Gamble Company Cleaning articles comprising a polarphobic region and a high internal phase inverse emulsion
US5980922A (en) * 1996-04-30 1999-11-09 Procter & Gamble Company Cleaning articles treated with a high internal phase inverse emulsion
US5908707A (en) * 1996-12-05 1999-06-01 The Procter & Gamble Company Cleaning articles comprising a high internal phase inverse emulsion and a carrier with controlled absorbency
US6018679A (en) * 1997-01-29 2000-01-25 Novartis Finance Corp. Iontophoretic transdermal delivery and control of adverse side-effects
US6133166A (en) * 1997-07-01 2000-10-17 The Procter & Gamble Company Cleaning articles comprising a cellulosic fibrous structure having discrete basis weight regions treated with a high internal phase inverse emulsion
BR9811718A (pt) * 1997-07-31 2000-08-15 Procter & Gamble Artigo de limpeza com carga úmida
SE9703691D0 (sv) * 1997-10-10 1997-10-10 Astra Ab Pharmaceutical compositions
DK1112275T3 (da) 1998-09-09 2003-11-24 Metabasis Therapeutics Inc Hidtil ukendte heteroaromatiske inhibitorer for fructose-1,6-bisphosphatase
US6495229B1 (en) * 1999-09-17 2002-12-17 Avery Dennison Corporation Pattern coated adhesive article
IL149887A0 (en) * 1999-12-22 2002-11-10 Metabasis Therapeutics Inc Novel bisamidate phosphonate prodrugs
PE20011061A1 (es) 2000-02-01 2001-11-20 Procter & Gamble Cristalizacion selectiva del acido 3-piridil-1-hidroxi-etiliden-1,1-bisfosfonico sodio como el hemipentahidrato o el monohidrato
US7563774B2 (en) * 2000-06-29 2009-07-21 Metabasis Therapeutics, Inc. Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes
WO2002000289A1 (fr) * 2000-06-30 2002-01-03 Phillip Roy Caskey Amelioration apportees a des methodes et a des appareils destines a l'application de miel sur des plaies
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
US6613347B2 (en) * 2001-02-21 2003-09-02 Tolland Development Company, Llc PVA sponge with low durometer skin silicone
EP1435970A4 (fr) * 2001-10-18 2005-05-04 Ilex Products Inc Methode de traitement de la peau avec des derives de diphosphonate
US20030124174A1 (en) * 2001-10-25 2003-07-03 Endo Pharmaceuticals, Inc Method for treating non-neuropathic pain
JP4546704B2 (ja) * 2002-02-14 2010-09-15 救急薬品工業株式会社 経皮投与製剤
TW200306847A (en) * 2002-02-14 2003-12-01 Yamanouchi Pharma Co Ltd Percutaneous preparations
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
WO2004037225A2 (fr) 2002-10-25 2004-05-06 Foamix Ltd. Mousse cosmetique et pharmaceutique
US9211259B2 (en) * 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
DK1589973T4 (da) * 2003-01-23 2013-04-08 Shire Biopharmaceuticals Holdings Ireland Ltd Formulering og fremgangsmåder til behandling af thrombocytæmi
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US20050112183A1 (en) * 2003-11-25 2005-05-26 Galer Bradley S. Compositions and methods for treating neuropathic sensory loss
US20060030574A1 (en) * 2004-08-04 2006-02-09 Shire Holdings Ag Quinazoline derivatives useful for the treatment of peripheral arterial disease and as phosphodiesterase inhibitors
US7700608B2 (en) * 2004-08-04 2010-04-20 Shire Holdings Ag Quinazoline derivatives and their use in the treatment of thrombocythemia
BRPI0514372A (pt) * 2004-08-18 2008-06-10 Metabasis Therapeutics Inc inibidores de tiazol de frutose 1, 6-bisfosfatase
EP2062584A1 (fr) 2006-09-11 2009-05-27 Kyukyu Pharmaceutical Co., Ltd. Préparation adhésive
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
JP2010510195A (ja) * 2006-11-17 2010-04-02 ベシンズ・ヘルスケアー ビスホスホネート化合物を含む液体薬剤組成物
US7910597B2 (en) * 2006-11-28 2011-03-22 Shire Llc Substituted quinazolines
US8304420B2 (en) 2006-11-28 2012-11-06 Shire Llc Substituted quinazolines for reducing platelet count
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (fr) 2007-11-30 2009-06-04 Foamix Ltd. Peroxyde de benzoyle contenant de la mousse
WO2009090495A2 (fr) 2007-12-07 2009-07-23 Foamix Ltd. Vecteurs moussants siliconés à base d'huile et de liquide, et formulations
WO2010041141A2 (fr) 2008-10-07 2010-04-15 Foamix Ltd. Support expansible à base d’huile et préparations
FR2926081B1 (fr) * 2008-01-03 2010-02-19 Univ Nantes Derives d'acide hydroxy-bisphosphonique comme vecteur ciblant le tissu osseux
CA2712120A1 (fr) 2008-01-14 2009-07-23 Foamix Ltd. Compositions pharmaceutiques pouvant mousser de poloxamere avec des agents actifs et/ou des cellules therapeutiques, et utilisations
US8323687B2 (en) 2008-03-18 2012-12-04 Aleksander Vladimirovich Dikovskiy Pharmaceutical composition for the prevention and treatment of bone tissue resorption of various etiology
WO2010125470A2 (fr) 2009-04-28 2010-11-04 Foamix Ltd. Véhicule moussant et compositions pharmaceutiques comportant des solvants polaires aprotiques et leurs utilisations
WO2011013009A2 (fr) 2009-07-29 2011-02-03 Foamix Ltd. Compositions hydro-alcooliques moussantes non tensioactives, mousses légères, et leurs utilisations
CA2769677A1 (fr) 2009-07-29 2011-02-03 Foamix Ltd. Compositions hydro-alcooliques moussantes a base d'agents non tensioactifs non polymeres, mousses legeres, et leurs utilisations
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
WO2011064631A1 (fr) 2009-10-02 2011-06-03 Foamix Ltd. Compositions moussantes dépourvues d'agent tensioactif et d'eau et mousses cassables et leurs utilisations
EP2766446A1 (fr) * 2011-10-12 2014-08-20 Dow Corning Corporation Compositions adhésives de gel de silicone de viscosité élevée
US10398641B2 (en) 2016-09-08 2019-09-03 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3683080A (en) * 1970-08-28 1972-08-08 Procter & Gamble Compositions for inhibiting anomalous deposition and mobilization of calcium phosphate in animal tissue
DE2405254C2 (de) * 1974-02-04 1982-05-27 Henkel KGaA, 4000 Düsseldorf Verwendung von 3-Amino-1-Hydroxypropan-1, 1-diphosphonsäure oder ihrer wasserlöslichen Salze bei der Beeinflußung von Calciumstoffwechselstörungen im menschlichen oder tierischen Körper
US4134969A (en) * 1974-02-04 1979-01-16 Henkel Kommanditgesellschaft Auf Aktien (Henkel Kgaa) Method of treatment of calcium disorders using aminoalkane-diphosphonic acids
DE2534391C2 (de) * 1975-08-01 1983-01-13 Henkel KGaA, 4000 Düsseldorf 1-Hydroxy-3-aminoalkan-1,1-diphosphonsäuren
DK506476A (da) * 1975-12-01 1977-06-02 Henkel & Cie Gmbh Farmaceutiske preparater til behandling af calciumstofs skifteforstyrrelser
AU2649977A (en) * 1976-07-15 1979-01-04 Procter & Gamble Pharmaceutical composition
DE2813121A1 (de) * 1977-03-29 1978-10-12 Procter & Gamble Verwendung von dichlormethan-diphosphonatverbindungen bei der bekaempfung von collagen-erkrankungen und zur wundheilung
DE2943498C2 (de) * 1979-10-27 1983-01-27 Henkel KGaA, 4000 Düsseldorf Verfahren zur Herstellung von 3-Amino-1-hydroxypropan-1,1-diphosphonsäure
BE890453A (fr) * 1980-10-07 1982-03-22 Procter & Gamble Procede d'inhibition des metastases de cellules tumorales
US4634691A (en) * 1980-10-07 1987-01-06 The Procter & Gamble Company Method for inhibiting tumor metastasis
US4304734A (en) * 1980-10-16 1981-12-08 Vysoka Skola Chemicko-Technologicka 6-Amino-1-hydroxyhexylidene diphosphonic acid, salts and a process for production thereof
DK154260C (da) * 1981-02-20 1989-05-22 Mundipharma Gmbh Fremgangsmaade til fremstilling af et knogleimplantat af braendt tricalciumphosphat, specielt til udfyldning af hulrum eller til sammensaetning af knogledele efter fraktur.
CA1248450A (fr) * 1984-04-05 1989-01-10 Kazuo Kigasawa Piece molle
DE3428524A1 (de) * 1984-08-02 1986-02-13 Boehringer Mannheim Gmbh, 6800 Mannheim Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
IL77243A (en) * 1984-12-21 1996-11-14 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds
US4687768A (en) * 1984-12-21 1987-08-18 The Procter & Gamble Company Certain hexahydroindan-2,2-diphosphonic acids useful in treating diseases associated with abnormal calcium and phosphate metabolism
US4597961A (en) * 1985-01-23 1986-07-01 Etscorn Frank T Transcutaneous application of nicotine
DE3512536A1 (de) * 1985-04-06 1986-10-16 Boehringer Mannheim Gmbh, 6800 Mannheim Neue diphosphonsaeure-derivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US4761406A (en) * 1985-06-06 1988-08-02 The Procter & Gamble Company Regimen for treating osteoporosis
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
GB8618259D0 (en) * 1986-07-25 1986-09-03 Leo Pharm Prod Ltd Pharmaceutical compositions
DE3626058A1 (de) * 1986-08-01 1988-02-11 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE10199052I1 (de) * 1986-11-21 2002-01-10 Novartis Ag Neue substituierte Alkandiphosphonsaeuren
EP0272208B1 (fr) * 1986-11-21 1991-06-12 Ciba-Geigy Ag Acides azacycloalkylalcanediphosphoniques substitués aromatiquement
DE3640938A1 (de) * 1986-11-29 1988-06-01 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindung enthaltende arzneimittel
EP0317505A1 (fr) * 1987-11-13 1989-05-24 Ciba-Geigy Ag Acides azacycloalkylalcanediphosphoniques
US4877618A (en) * 1988-03-18 1989-10-31 Reed Jr Fred D Transdermal drug delivery device

Also Published As

Publication number Publication date
PT94611A (pt) 1991-04-18
AU633598B2 (en) 1993-02-04
DD296418A5 (de) 1991-12-05
NZ234377A (en) 1992-12-23
US5133972A (en) 1992-07-28
HUT54502A (en) 1991-03-28
EP0407344A2 (fr) 1991-01-09
IE902481A1 (en) 1991-02-13
PT94611B (pt) 1997-02-28
IL94926A (en) 1994-10-21
KR910002432A (ko) 1991-02-25
FI903382A0 (fi) 1990-07-04
JPH0344328A (ja) 1991-02-26
EP0407344A3 (en) 1991-06-12
CA2020557A1 (fr) 1991-01-08
HU904122D0 (en) 1990-12-28
AU5869890A (en) 1991-01-10
MX21452A (es) 1994-01-31

Similar Documents

Publication Publication Date Title
ZA905306B (en) Topically administrable pharmaceutical preparations
CS419991A3 (en) Pharmaceutical preparations
GB8421706D0 (en) Pharmaceutical preparations
EP0207451A3 (en) Pharmaceutical preparations
GB8607749D0 (en) Compounds & pharmaceutical preparations
GB8520189D0 (en) Pharmaceutical preparations
ZA852279B (en) Pharmaceutical preparations
GB8719375D0 (en) Pharmaceutical preparations
GR871678B (en) Analgesic preparations
ZA906186B (en) Pharmaceutical preparations
GB8906129D0 (en) Pharmaceutical preparations
GB8506388D0 (en) Pharmaceutical preparations
ZA875281B (en) Zylometzoline-containing pharmaceutical preparations
IE890944L (en) Pharmaceutical preparations
IE890022L (en) Pharmaceutical preparations
GB8914612D0 (en) Pharmaceutical preparations
GB8914610D0 (en) Pharmaceutical preparations
GB8914611D0 (en) Pharmaceutical preparations
GB8914613D0 (en) Pharmaceutical preparations
IE890776L (en) Topical preparations
GB8316087D0 (en) Topical pharmaceutical preparations
IE892741L (en) Pharmaceutical combination preparations
IE871199L (en) Pharmaceutical preparations
GB8701271D0 (en) Pharmaceutical preparations
IE873302L (en) Pharmaceutical preparations