ZA904583B - Leukotriene antagonists - Google Patents
Leukotriene antagonistsInfo
- Publication number
- ZA904583B ZA904583B ZA904583A ZA904583A ZA904583B ZA 904583 B ZA904583 B ZA 904583B ZA 904583 A ZA904583 A ZA 904583A ZA 904583 A ZA904583 A ZA 904583A ZA 904583 B ZA904583 B ZA 904583B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkoxy
- alkyl
- cor3
- trifluoromethylthio
- tetrazolyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/02—Monothiocarboxylic acids
- C07C327/04—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C327/08—Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton containing rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36604689A | 1989-06-14 | 1989-06-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA904583B true ZA904583B (en) | 1992-05-27 |
Family
ID=23441449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA904583A ZA904583B (en) | 1989-06-14 | 1990-06-13 | Leukotriene antagonists |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0403249B1 (fr) |
JP (1) | JPH0324050A (fr) |
KR (1) | KR910000632A (fr) |
AT (1) | ATE104955T1 (fr) |
AU (1) | AU645253B2 (fr) |
CA (1) | CA2018437A1 (fr) |
DE (1) | DE69008428T2 (fr) |
DK (1) | DK0403249T3 (fr) |
ES (1) | ES2063271T3 (fr) |
IE (1) | IE902141A1 (fr) |
MX (1) | MX21139A (fr) |
NZ (1) | NZ234009A (fr) |
PT (1) | PT94373A (fr) |
ZA (1) | ZA904583B (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5214201A (en) * | 1991-12-12 | 1993-05-25 | Smithkline Beecham Corporation | Crystallization of optical isomers of leukotriene antagonists |
WO1993017709A1 (fr) * | 1992-03-12 | 1993-09-16 | Ono Pharmaceutical Co., Ltd. | Agent antiprurigineux |
CN1100092A (zh) * | 1992-12-23 | 1995-03-15 | 史密丝克莱恩比彻姆公司 | 砜的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES8700647A1 (es) * | 1984-10-11 | 1986-11-16 | Raychem Corp | Procedimiento para la preparacion de un compuesto carbonilo aromatico |
CA1334200C (fr) * | 1987-06-24 | 1995-01-31 | James Simpson Frazee | Antagonistes du leucotriene |
AU610528B2 (en) * | 1987-10-29 | 1991-05-23 | Smithkline Beckman Corporation | Leukotriene antagonists |
JPH01153658A (ja) * | 1987-12-08 | 1989-06-15 | E R Squibb & Sons Inc | ヘテロ含有置換基を有するフェニルヒドロキサム酸類 |
US4954513A (en) * | 1988-12-23 | 1990-09-04 | Smithkline Beecham Corporation | Leukotriene antagonists |
-
1990
- 1990-06-07 CA CA002018437A patent/CA2018437A1/fr not_active Abandoned
- 1990-06-08 AU AU56902/90A patent/AU645253B2/en not_active Ceased
- 1990-06-11 NZ NZ234009A patent/NZ234009A/xx unknown
- 1990-06-12 PT PT94373A patent/PT94373A/pt not_active Application Discontinuation
- 1990-06-13 MX MX2113990A patent/MX21139A/es unknown
- 1990-06-13 DE DE69008428T patent/DE69008428T2/de not_active Expired - Fee Related
- 1990-06-13 IE IE214190A patent/IE902141A1/en unknown
- 1990-06-13 DK DK90306438.4T patent/DK0403249T3/da active
- 1990-06-13 AT AT9090306438T patent/ATE104955T1/de not_active IP Right Cessation
- 1990-06-13 JP JP2154990A patent/JPH0324050A/ja active Pending
- 1990-06-13 ZA ZA904583A patent/ZA904583B/xx unknown
- 1990-06-13 ES ES90306438T patent/ES2063271T3/es not_active Expired - Lifetime
- 1990-06-13 EP EP90306438A patent/EP0403249B1/fr not_active Expired - Lifetime
- 1990-06-14 KR KR1019900008738A patent/KR910000632A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ES2063271T3 (es) | 1995-01-01 |
CA2018437A1 (fr) | 1990-12-14 |
IE902141A1 (en) | 1991-01-02 |
DE69008428D1 (de) | 1994-06-01 |
DE69008428T2 (de) | 1994-11-24 |
EP0403249B1 (fr) | 1994-04-27 |
MX21139A (es) | 1993-12-01 |
AU5690290A (en) | 1990-12-20 |
KR910000632A (ko) | 1991-01-29 |
ATE104955T1 (de) | 1994-05-15 |
EP0403249A1 (fr) | 1990-12-19 |
IE902141L (en) | 1990-12-14 |
JPH0324050A (ja) | 1991-02-01 |
AU645253B2 (en) | 1994-01-13 |
PT94373A (pt) | 1991-02-08 |
NZ234009A (en) | 1993-02-25 |
DK0403249T3 (da) | 1994-05-24 |
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