JPS57200372A - Novel 5-substituted-2-((n-morpholino)-n-nitrosoamino- methyl)oxadiazole derivative and preventing agent for thrombosis containing the same as principal constituent - Google Patents
Novel 5-substituted-2-((n-morpholino)-n-nitrosoamino- methyl)oxadiazole derivative and preventing agent for thrombosis containing the same as principal constituentInfo
- Publication number
- JPS57200372A JPS57200372A JP8500081A JP8500081A JPS57200372A JP S57200372 A JPS57200372 A JP S57200372A JP 8500081 A JP8500081 A JP 8500081A JP 8500081 A JP8500081 A JP 8500081A JP S57200372 A JPS57200372 A JP S57200372A
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- nitrosoamino
- morpholino
- substituted
- preventing agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
NEW MATERIAL:A 5-substituted-2-[( N-morpholino )-N-nitrosoamino-methyl]-1,3, 4-oxadiazole derivative expressed by formulaI(R is 1W3C alkyl, phenyl or p- dimethylaminophenyl).
EXAMPLE: 5-Methyl-2-[(N-morpholino)-N-nitrosoamino-methyl]-1,3,4-oxadiazole.
USE: A preventing agent for thrombosis.
PROCESS: A 5-substituted-2-[(N-morpholinoamino)-methyl]oxadiazole expressed by formula II is nitrosated with NaNO2 to give the compound expressed by formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8500081A JPS57200372A (en) | 1981-06-04 | 1981-06-04 | Novel 5-substituted-2-((n-morpholino)-n-nitrosoamino- methyl)oxadiazole derivative and preventing agent for thrombosis containing the same as principal constituent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8500081A JPS57200372A (en) | 1981-06-04 | 1981-06-04 | Novel 5-substituted-2-((n-morpholino)-n-nitrosoamino- methyl)oxadiazole derivative and preventing agent for thrombosis containing the same as principal constituent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57200372A true JPS57200372A (en) | 1982-12-08 |
JPH0160027B2 JPH0160027B2 (en) | 1989-12-20 |
Family
ID=13846370
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8500081A Granted JPS57200372A (en) | 1981-06-04 | 1981-06-04 | Novel 5-substituted-2-((n-morpholino)-n-nitrosoamino- methyl)oxadiazole derivative and preventing agent for thrombosis containing the same as principal constituent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57200372A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0495776A1 (en) * | 1989-02-28 | 1992-07-29 | Us Health | Stabilized nitric oxide-primary amine complexes useful as cardiovascular agents. |
-
1981
- 1981-06-04 JP JP8500081A patent/JPS57200372A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0495776A1 (en) * | 1989-02-28 | 1992-07-29 | Us Health | Stabilized nitric oxide-primary amine complexes useful as cardiovascular agents. |
Also Published As
Publication number | Publication date |
---|---|
JPH0160027B2 (en) | 1989-12-20 |
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