JPS57200372A - Novel 5-substituted-2-((n-morpholino)-n-nitrosoamino- methyl)oxadiazole derivative and preventing agent for thrombosis containing the same as principal constituent - Google Patents

Novel 5-substituted-2-((n-morpholino)-n-nitrosoamino- methyl)oxadiazole derivative and preventing agent for thrombosis containing the same as principal constituent

Info

Publication number
JPS57200372A
JPS57200372A JP8500081A JP8500081A JPS57200372A JP S57200372 A JPS57200372 A JP S57200372A JP 8500081 A JP8500081 A JP 8500081A JP 8500081 A JP8500081 A JP 8500081A JP S57200372 A JPS57200372 A JP S57200372A
Authority
JP
Japan
Prior art keywords
methyl
nitrosoamino
morpholino
substituted
preventing agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8500081A
Other languages
Japanese (ja)
Other versions
JPH0160027B2 (en
Inventor
Hiroyoshi Hidaka
Masatoshi Ban
Yasuaki Kondo
Tomoo Suzuki
Eiichi Suenaga
Akiji Kuwayama
Hiromoto Asai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanwa Kagaku Kenkyusho Co Ltd
Original Assignee
Sanwa Kagaku Kenkyusho Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanwa Kagaku Kenkyusho Co Ltd filed Critical Sanwa Kagaku Kenkyusho Co Ltd
Priority to JP8500081A priority Critical patent/JPS57200372A/en
Publication of JPS57200372A publication Critical patent/JPS57200372A/en
Publication of JPH0160027B2 publication Critical patent/JPH0160027B2/ja
Granted legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

NEW MATERIAL:A 5-substituted-2-[( N-morpholino )-N-nitrosoamino-methyl]-1,3, 4-oxadiazole derivative expressed by formulaI(R is 1W3C alkyl, phenyl or p- dimethylaminophenyl).
EXAMPLE: 5-Methyl-2-[(N-morpholino)-N-nitrosoamino-methyl]-1,3,4-oxadiazole.
USE: A preventing agent for thrombosis.
PROCESS: A 5-substituted-2-[(N-morpholinoamino)-methyl]oxadiazole expressed by formula II is nitrosated with NaNO2 to give the compound expressed by formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP8500081A 1981-06-04 1981-06-04 Novel 5-substituted-2-((n-morpholino)-n-nitrosoamino- methyl)oxadiazole derivative and preventing agent for thrombosis containing the same as principal constituent Granted JPS57200372A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8500081A JPS57200372A (en) 1981-06-04 1981-06-04 Novel 5-substituted-2-((n-morpholino)-n-nitrosoamino- methyl)oxadiazole derivative and preventing agent for thrombosis containing the same as principal constituent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8500081A JPS57200372A (en) 1981-06-04 1981-06-04 Novel 5-substituted-2-((n-morpholino)-n-nitrosoamino- methyl)oxadiazole derivative and preventing agent for thrombosis containing the same as principal constituent

Publications (2)

Publication Number Publication Date
JPS57200372A true JPS57200372A (en) 1982-12-08
JPH0160027B2 JPH0160027B2 (en) 1989-12-20

Family

ID=13846370

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8500081A Granted JPS57200372A (en) 1981-06-04 1981-06-04 Novel 5-substituted-2-((n-morpholino)-n-nitrosoamino- methyl)oxadiazole derivative and preventing agent for thrombosis containing the same as principal constituent

Country Status (1)

Country Link
JP (1) JPS57200372A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0495776A1 (en) * 1989-02-28 1992-07-29 Us Health Stabilized nitric oxide-primary amine complexes useful as cardiovascular agents.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0495776A1 (en) * 1989-02-28 1992-07-29 Us Health Stabilized nitric oxide-primary amine complexes useful as cardiovascular agents.

Also Published As

Publication number Publication date
JPH0160027B2 (en) 1989-12-20

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