ZA90387B - New benzopyran derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

New benzopyran derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
ZA90387B
ZA90387B ZA90387A ZA90387A ZA90387B ZA 90387 B ZA90387 B ZA 90387B ZA 90387 A ZA90387 A ZA 90387A ZA 90387 A ZA90387 A ZA 90387A ZA 90387 B ZA90387 B ZA 90387B
Authority
ZA
South Africa
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
benzopyran derivatives
new benzopyran
Prior art date
Application number
ZA90387A
Other languages
English (en)
Inventor
Michel Barreau
Barreau Michel
Jean-Claude Hardy
Hardy Jean-Claude
Jean-Paul Martin
Martin Jean-Paul
Christian Renault
Renault Christian
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of ZA90387B publication Critical patent/ZA90387B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
ZA90387A 1989-01-20 1990-01-19 New benzopyran derivatives,their preparation and pharmaceutical compositions containing them ZA90387B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8900657A FR2642069B1 (fr) 1989-01-20 1989-01-20 Nouveaux derives du benzopyranne, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA90387B true ZA90387B (en) 1991-11-27

Family

ID=9377904

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA90387A ZA90387B (en) 1989-01-20 1990-01-19 New benzopyran derivatives,their preparation and pharmaceutical compositions containing them

Country Status (12)

Country Link
US (1) US5025013A (xx)
EP (1) EP0379441A1 (xx)
JP (1) JPH02233675A (xx)
KR (1) KR900011760A (xx)
AU (1) AU622265B2 (xx)
CA (1) CA2008157A1 (xx)
FI (1) FI900313A0 (xx)
FR (1) FR2642069B1 (xx)
HU (1) HUT58078A (xx)
NO (1) NO900276L (xx)
PT (1) PT92916A (xx)
ZA (1) ZA90387B (xx)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5240943A (en) * 1991-12-19 1993-08-31 G. D. Searle & Co. Benzopyran class iii antiarrhythmic agents
FR2705674B1 (fr) * 1993-05-26 1996-01-05 Smithkline Beecham Labo Pharma Nouveaux composés et leur procédé de préparation et leur utilisation en tant que médicaments.
AU6971794A (en) * 1993-05-26 1994-12-20 Smithkline Beecham Laboratoires Pharmaceutiques Novel compounds
IL136421A0 (en) * 1995-12-15 2001-06-14 Pfizer Intermediates for preparing 1-benzyl -4-((5,6- dimethoxy -1-indanon)-2-yl) methylpiperidine
DE10000739A1 (de) * 2000-01-11 2001-07-12 Merck Patent Gmbh Piperidin- und Piperazinderivate
CA2397981C (en) 2000-03-06 2010-12-21 Acadia Pharmaceuticals, Inc. Azacyclic compounds for use in the treatment of serotonin related diseases
WO2001081308A2 (en) * 2000-04-20 2001-11-01 Nps Allelix Corp. Aminopiperidines for use as glyt-1 inhibitors
WO2003057698A2 (en) * 2001-12-28 2003-07-17 Acadia Pharmaceuticals, Inc. Spiroazacyclic compounds as monoamine receptor modulators
WO2004000808A2 (en) * 2002-06-24 2003-12-31 Acadia Pharmaceuticals Inc. N-substituted piperidine derivatives as serotonin receptor agents
US7253186B2 (en) * 2002-06-24 2007-08-07 Carl-Magnus Andersson N-substituted piperidine derivatives as serotonin receptor agents
US7538222B2 (en) * 2002-06-24 2009-05-26 Acadia Pharmaceuticals, Inc. N-substituted piperidine derivatives as serotonin receptor agents
MY139563A (en) * 2002-09-04 2009-10-30 Bristol Myers Squibb Co Heterocyclic aromatic compounds useful as growth hormone secretagogues
KR101095939B1 (ko) 2003-01-16 2011-12-19 아카디아 파마슈티칼스 인코포레이티드 신경퇴행성 질환에 대한 치료제로서 선택적 세로토닌2ａ／2ｃ 리셉터 역작용제
NZ544046A (en) * 2003-06-17 2009-08-28 Pfizer N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenaline re-uptake inhibitors
US20050261278A1 (en) * 2004-05-21 2005-11-24 Weiner David M Selective serotonin receptor inverse agonists as therapeutics for disease
US7820695B2 (en) * 2004-05-21 2010-10-26 Acadia Pharmaceuticals, Inc. Selective serotonin receptor inverse agonists as therapeutics for disease
SG157378A1 (en) * 2004-09-27 2009-12-29 Acadia Pharm Inc Salts of n-(4-fluorobenzyl)-n-(1-methylpiperidin-4-yl)-næ-(4-(2- methylpropyloxy)phenylmethyl)carbamide and their preparation
US7790899B2 (en) * 2004-09-27 2010-09-07 Acadia Pharmaceuticals, Inc. Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms
DK2134330T3 (da) 2007-03-19 2013-08-05 Acadia Pharm Inc Kominationer af 5-ht2a-inverse agonister og antagonister med antipsykotika
EP2481735A1 (en) * 2007-05-09 2012-08-01 Pfizer Inc. Substituted heterocyclic derivatives and compositions and their pharmaceutical use as antibacterials
EP2200610B1 (en) * 2007-09-21 2018-01-10 Acadia Pharmaceuticals Inc. Co-administration of pimavanserin with other agents
PT3325444T (pt) 2015-07-20 2021-09-22 Acadia Pharm Inc Métodos para preparar n-(4-fluorobenzil)-n-(1-metilpiperidina-4-il)-n'-(4-(2-metilpropiloxi)fenilmetil)carbamida e o seu sal de tartarato e forma polimórfica c
US10953000B2 (en) 2016-03-25 2021-03-23 Acadia Pharmaceuticals Inc. Combination of pimavanserin and cytochrome P450 modulators
WO2017165635A1 (en) 2016-03-25 2017-09-28 Acadia Pharmaceuticals Inc. Combination of pimavanserin and cytochrome p450 modulators
EP3558311A1 (en) 2016-12-20 2019-10-30 Acadia Pharmaceuticals Inc. Pimavanserin alone or in combination for use in the treatment of alzheimer's disease psychosis
US11135211B2 (en) 2017-04-28 2021-10-05 Acadia Pharmaceuticals Inc. Pimavanserin for treating impulse control disorder
EP3675827A1 (en) 2017-08-30 2020-07-08 Acadia Pharmaceuticals Inc. Formulations of pimavanserin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3300004A1 (de) * 1983-01-03 1984-07-12 Bayer Ag, 5090 Leverkusen Substituierte 4-aminomethylenchromane bzw. -chromene, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
FR2618437B1 (fr) * 1987-07-23 1989-11-17 Rhone Poulenc Sante Nouveaux derives du benzopyranne, leur preparation et les medicaments qui les contiennent
EP0322361A3 (de) * 1987-12-23 1990-01-24 Ciba-Geigy Ag Weitere hydrierte 1-Benzooxacycloalkylpyridincarbonsäureverbindungen

Also Published As

Publication number Publication date
US5025013A (en) 1991-06-18
CA2008157A1 (fr) 1990-07-20
NO900276L (no) 1990-07-23
FR2642069A1 (fr) 1990-07-27
FI900313A0 (fi) 1990-01-19
HU900206D0 (en) 1990-03-28
KR900011760A (ko) 1990-08-02
FR2642069B1 (fr) 1991-04-12
PT92916A (pt) 1990-07-31
NO900276D0 (no) 1990-01-19
AU622265B2 (en) 1992-04-02
HUT58078A (en) 1992-01-28
JPH02233675A (ja) 1990-09-17
EP0379441A1 (fr) 1990-07-25
AU4858490A (en) 1990-07-26

Similar Documents

Publication Publication Date Title
IL96516A0 (en) Benzofuran derivatives,their preparation and pharmaceutical compositions containing them
IL86923A0 (en) Benzopyran derivatives,their preparation and pharmaceutical compositions containing them
ZA90387B (en) New benzopyran derivatives,their preparation and pharmaceutical compositions containing them
IL95045A0 (en) Thienodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL91129A0 (en) Aminomethyloxooxazolidinyl arylbenzene derivatives,their preparation and pharmaceutical compositions containing them
IL90245A0 (en) Ethenediamine derivatives,their preparation and pharmaceutical compositions containing them
IL94082A0 (en) 3-n-substituted carbamoyl-indole derivatives,their preparation and pharmaceutical compositions containing them
IL90350A0 (en) Benzopyran derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL91005A0 (en) Furan derivatives,their preparation and pharmaceutical compositions containing them
IL93105A0 (en) Imidazole derivatives,their preparation and pharmaceutical compositions containing them
IL94556A0 (en) Hydroxypropylamines,their preparation and pharmaceutical compositions containing them
IL93124A0 (en) Benzocycloalkenyldihydroxyalkanoic-acid derivatives,their preparation and pharmaceutical compositions
IL88035A0 (en) Benzopyran derivatives,their preparation and pharmaceutical compositions containing them
IL95936A0 (en) Phenethanolamine derivatives,their preparation and pharmaceutical compositions containing them
IL92710A (en) 2-iminobenzothiazoline derivatives, their preparation and pharmaceutical compositions containing them
IL89084A0 (en) Benzodioxole derivatives,their preparation and pharmaceutical compositions containing them
IL91245A0 (en) Benzopyranol derivatives,their preparation and pharmaceutical compositions containing them
IL90002A0 (en) Phosphonoalkylpurine derivatives,their preparation and pharmaceutical compositions containing them
IL90324A0 (en) 2-aminoethanol derivatives,their preparation and pharmaceutical compositions containing them
IL96252A0 (en) Pyridine derivatives,their preparation and pharmaceutical compositions containing them
IL93750A0 (en) Tetrahydronaphthalene derivatives,their preparation and pharmaceutical compositions containing them
IL74166A (en) Benzopyran derivatives,their preparation and pharmaceutical compositions containing them
IL95563A0 (en) Substituted amino-pyridines,their preparation and pharmaceutical compositions containing them
IL93676A0 (en) Anthracycline derivatives,their preparation and pharmaceutical compositions containing them
ZA90357B (en) New benzopyran derivatives,their preparation and pharmaceutical compositions containing them