ZA903225B - Tetrahydroisoquino(2,1-c)(1,3)benzodiazepines,a process for their preparation and their use as medicaments - Google Patents

Tetrahydroisoquino(2,1-c)(1,3)benzodiazepines,a process for their preparation and their use as medicaments

Info

Publication number
ZA903225B
ZA903225B ZA903225A ZA903225A ZA903225B ZA 903225 B ZA903225 B ZA 903225B ZA 903225 A ZA903225 A ZA 903225A ZA 903225 A ZA903225 A ZA 903225A ZA 903225 B ZA903225 B ZA 903225B
Authority
ZA
South Africa
Prior art keywords
tetrahydroisoquino
benzodiazepines
medicaments
preparation
Prior art date
Application number
ZA903225A
Other languages
English (en)
Inventor
Lawrence Leo Martin
Leo Martin Lawrence
Richard C Allen
C Allen Richard
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of ZA903225B publication Critical patent/ZA903225B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA903225A 1989-04-28 1990-04-27 Tetrahydroisoquino(2,1-c)(1,3)benzodiazepines,a process for their preparation and their use as medicaments ZA903225B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/344,799 US4908361A (en) 1989-04-28 1989-04-28 Tetrahydroisoquino(2,1-C)(1,3)benzodiazepines

Publications (1)

Publication Number Publication Date
ZA903225B true ZA903225B (en) 1991-02-27

Family

ID=23352091

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA903225A ZA903225B (en) 1989-04-28 1990-04-27 Tetrahydroisoquino(2,1-c)(1,3)benzodiazepines,a process for their preparation and their use as medicaments

Country Status (13)

Country Link
US (1) US4908361A (xx)
EP (1) EP0395065A1 (xx)
JP (1) JPH032182A (xx)
KR (1) KR900016209A (xx)
AU (1) AU619977B2 (xx)
CA (1) CA2015579A1 (xx)
FI (1) FI902119A0 (xx)
HU (2) HU206115B (xx)
IL (1) IL94221A0 (xx)
NO (1) NO901892L (xx)
NZ (1) NZ233440A (xx)
PT (1) PT93898A (xx)
ZA (1) ZA903225B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5919794A (en) * 1998-05-11 1999-07-06 Virginia Commonwealth University Methods of using pharmaceutical tetrahydroisoquinolines
CN115260094B (zh) * 2022-06-16 2024-04-05 珠海润都制药股份有限公司 一种新的盐酸去甲乌药碱的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3435038A (en) * 1965-06-01 1969-03-25 Sandoz Ag 5,6,7,9,10,14b-hexahydroisoquinolo (2,1-d) benzo (1,4) diazepines
US4309424A (en) * 1978-10-05 1982-01-05 Hoechst-Roussel Pharmaceuticals Incorporated 4-Phenyl-1,3-benzodiazepines
US4459230A (en) * 1979-11-05 1984-07-10 Hoechst-Roussel Pharmaceuticals, Incorporated Process for preparing 4-phenyl-1,3-benzodiazepines
US4459231A (en) * 1979-11-05 1984-07-10 Hoechst-Roussel Pharmaceuticals, Incorporated Process for preparing 4-phenyl-1,3-benzodiazepines

Also Published As

Publication number Publication date
NO901892D0 (no) 1990-04-27
NO901892L (no) 1990-10-29
EP0395065A1 (en) 1990-10-31
JPH032182A (ja) 1991-01-08
IL94221A0 (en) 1991-01-31
FI902119A0 (fi) 1990-04-26
US4908361A (en) 1990-03-13
HUT61528A (en) 1993-01-28
HU9200388D0 (en) 1992-04-28
KR900016209A (ko) 1990-11-12
AU619977B2 (en) 1992-02-06
AU5390790A (en) 1990-11-01
PT93898A (pt) 1990-11-20
CA2015579A1 (en) 1990-10-28
HU902605D0 (en) 1990-09-28
HU206115B (en) 1992-08-28
NZ233440A (en) 1992-07-28

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