ZA902591B - Thiouracil derivatives,pharmaceutical compositions containing them and process for preparing same - Google Patents

Thiouracil derivatives,pharmaceutical compositions containing them and process for preparing same

Info

Publication number
ZA902591B
ZA902591B ZA902591A ZA902591A ZA902591B ZA 902591 B ZA902591 B ZA 902591B ZA 902591 A ZA902591 A ZA 902591A ZA 902591 A ZA902591 A ZA 902591A ZA 902591 B ZA902591 B ZA 902591B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical compositions
compositions containing
preparing same
thiouracil derivatives
thiouracil
Prior art date
Application number
ZA902591A
Other languages
English (en)
Inventor
Gabor Zoelyomi
Zoelyomi Gabor
Ferenc Andrasii
Andrasii Ferenc
Pal Berzsenyi
Berzsenyi Pal
Elemer Ezer
Ezer Elemer
Tibor Hasko
Hasko Tibor
Emo Koitai
Koitai Emo
Erzsebet Faiglne Birkas
Faiglne Birkas Erzsebet
Judit Matuz
Matuz Judit
Lajos Toldy
Toldy Lajos
Laszlo Sebestyen
Sebestyen Laszlo
Zsuzsanna Fittler
Fittler Zsuzsanna
Katalin Saghy
Saghy Katalin
Laszlo Szporny
Szporny Laszlo
Peter Aranyi
Aranyi Peter
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ZA902591B publication Critical patent/ZA902591B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/38—One sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA902591A 1989-04-06 1990-04-04 Thiouracil derivatives,pharmaceutical compositions containing them and process for preparing same ZA902591B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU891653A HU203736B (en) 1989-04-06 1989-04-06 Process for producing new thiouracil-derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
ZA902591B true ZA902591B (en) 1991-01-30

Family

ID=10955534

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA902591A ZA902591B (en) 1989-04-06 1990-04-04 Thiouracil derivatives,pharmaceutical compositions containing them and process for preparing same

Country Status (15)

Country Link
US (1) US5037830A (xx)
EP (1) EP0391254A3 (xx)
JP (1) JPH0327363A (xx)
KR (1) KR900016154A (xx)
CN (1) CN1046158A (xx)
AU (1) AU5256290A (xx)
CA (1) CA2013916A1 (xx)
DD (1) DD293349A5 (xx)
FI (1) FI901775A0 (xx)
HU (1) HU203736B (xx)
IL (1) IL93855A0 (xx)
NZ (1) NZ233121A (xx)
PT (1) PT93677A (xx)
RU (1) RU1777601C (xx)
ZA (1) ZA902591B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0853424A (ja) * 1994-08-11 1996-02-27 Kureha Chem Ind Co Ltd ベンズイミダゾールスルホン酸アミド誘導体
UA56992C2 (uk) * 1995-05-08 2003-06-16 Фармація Енд Апджон Компані <font face="Symbol">a</font>-ПІРИМІДИНТІОАЛКІЛЗАМІЩЕНІ ТА <font face="Symbol">a</font>-ПІРИМІДИНОКСОАЛКІЛЗАМІЩЕНІ СПОЛУКИ
EP1028955B1 (en) 1997-11-06 2003-07-16 SmithKline Beecham plc Pyrimidinone compounds and pharmaceutical compositions containing them
WO2000013688A1 (en) 1998-09-04 2000-03-16 Agouron Pharmaceuticals, Inc. Compounds useful as aicarft inhibitors
GB9910079D0 (en) * 1999-05-01 1999-06-30 Smithkline Beecham Plc Novel compounds
US7347223B2 (en) * 2003-07-21 2008-03-25 The Metraflex Company Pipe flow stabilizer
WO2010132999A1 (en) 2009-05-21 2010-11-25 Chlorion Pharma, Inc. Methyl sulfanyl pyrmidmes useful as antiinflammatories, analgesics, and antiepileptics
US11993580B1 (en) 2022-12-02 2024-05-28 Neumora Therapeutics, Inc. Methods of treating neurological disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045564A (en) * 1974-02-18 1977-08-30 Ab Hassle Benzimidazole derivatives useful as gastric acid secretion inhibitors
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
EP0124630B1 (de) * 1983-05-05 1987-01-28 LUDWIG HEUMANN &amp; CO GMBH Pyrimidin-Thioalkylpyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindung enthaltende Arzneimittel
US4542216A (en) * 1984-03-27 1985-09-17 Ciba Geigy Corporation Process for producing fluoroalkoxyaminopyrimidines
JPH07107056B2 (ja) * 1987-01-30 1995-11-15 日清製粉株式会社 ４（３ｈ）−キナゾリノン誘導体、その製造方法およびそれを有効成分とする抗潰瘍剤

Also Published As

Publication number Publication date
HU203736B (en) 1991-09-30
JPH0327363A (ja) 1991-02-05
EP0391254A3 (en) 1991-04-03
DD293349A5 (de) 1991-08-29
EP0391254A2 (en) 1990-10-10
KR900016154A (ko) 1990-11-12
FI901775A0 (fi) 1990-04-06
AU5256290A (en) 1990-10-11
HUT53620A (en) 1990-11-28
CA2013916A1 (en) 1990-10-06
IL93855A0 (en) 1990-12-23
PT93677A (pt) 1990-11-20
RU1777601C (ru) 1992-11-23
NZ233121A (en) 1992-04-28
CN1046158A (zh) 1990-10-17
US5037830A (en) 1991-08-06

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