ZA902378B - Cephalos porins and their homologues process for their preparation and pharmaceutical compositions - Google Patents

Cephalos porins and their homologues process for their preparation and pharmaceutical compositions

Info

Publication number
ZA902378B
ZA902378B ZA902378A ZA902378A ZA902378B ZA 902378 B ZA902378 B ZA 902378B ZA 902378 A ZA902378 A ZA 902378A ZA 902378 A ZA902378 A ZA 902378A ZA 902378 B ZA902378 B ZA 902378B
Authority
ZA
South Africa
Prior art keywords
preparation
cephalos
porins
homologues
pharmaceutical compositions
Prior art date
Application number
ZA902378A
Other languages
English (en)
Inventor
John Hargreaves Bateson
Hargreaves Bateson John
George Burton
Burton George
Stephen Christopher Marti Fell
Christopher Martin Fel Stephen
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898907171A external-priority patent/GB8907171D0/en
Priority claimed from GB898920791A external-priority patent/GB8920791D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of ZA902378B publication Critical patent/ZA902378B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA902378A 1989-03-30 1990-03-28 Cephalos porins and their homologues process for their preparation and pharmaceutical compositions ZA902378B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898907171A GB8907171D0 (en) 1989-03-30 1989-03-30 Novel compounds
GB898920791A GB8920791D0 (en) 1989-09-14 1989-09-14 Novel compounds

Publications (1)

Publication Number Publication Date
ZA902378B true ZA902378B (en) 1991-06-26

Family

ID=26295148

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA902378A ZA902378B (en) 1989-03-30 1990-03-28 Cephalos porins and their homologues process for their preparation and pharmaceutical compositions

Country Status (12)

Country Link
US (1) US5246926A (fr)
EP (1) EP0395219B1 (fr)
JP (1) JP2979235B2 (fr)
KR (1) KR900014403A (fr)
AT (1) ATE171705T1 (fr)
AU (1) AU625844B2 (fr)
CA (1) CA2013391A1 (fr)
DE (1) DE69032681T2 (fr)
DK (1) DK0395219T3 (fr)
ES (1) ES2121745T3 (fr)
PT (1) PT93602A (fr)
ZA (1) ZA902378B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332731A (en) * 1989-12-07 1994-07-26 Meiji Seika Kaisha, Ltd. Cephalosporin derivatives
MY106399A (en) * 1990-07-24 1995-05-30 Pfizer Cephalosporins and homologeus, preparation and pharmaceutical composition
US6020329A (en) * 1990-07-24 2000-02-01 Pzifer Inc. Cephaloporins and homologues, preparations and pharmaceutical compositions
US6001997A (en) * 1990-07-24 1999-12-14 Bateson; John Hargreaves Cephalosporins and homologues, preparations and pharmaceutical compositions
GB9019743D0 (en) * 1990-09-10 1990-10-24 Beecham Group Plc Novel compounds
DE4037841A1 (de) * 1990-11-28 1992-06-04 Bayer Ag Neue 3-substituierte cephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
IT1251643B (it) * 1991-10-29 1995-05-17 Mini Ricerca Scient Tecnolog Derivati maleimmidici contenenti residui acrilici
GB9125645D0 (en) * 1991-12-03 1992-01-29 Smithkline Beecham Plc Novel compounds
US5302711A (en) * 1992-02-18 1994-04-12 Eli Lilly And Company Ester cleavage process for use with β-lactams
GB9212609D0 (en) * 1992-06-13 1992-07-29 Smithkline Beecham Plc Novel compounds
GB9213567D0 (en) * 1992-06-26 1992-08-12 Smithkline Beecham Plc Novel compounds
US5604222A (en) 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
GB9424847D0 (en) * 1994-12-09 1995-02-08 Smithkline Beecham Plc Novel process
IT1277048B1 (it) * 1995-12-06 1997-11-04 3 Exo S R L Procedimento per la preparazione di cefalosporine attraverso ciclizzazione riduttiva dicarbonilica per trattamento con
EP1455900A1 (fr) * 2001-12-21 2004-09-15 Pfizer Products Inc. Procedes de traitement d'infections bacteriennes chez les chats et les chiens
US20040002600A1 (en) * 2002-06-20 2004-01-01 Orchid Chemicals And Pharmaceuticals Limited Process for the conversion of penam ring system to cepham ring system
MX2010003112A (es) * 2007-09-21 2010-08-11 Astrazeneca Ab Formas de dosificacion solubles que contienen derivados de cephem adecuados para administracion parenteral.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868173A (en) * 1984-11-20 1989-09-19 Ici Pharma Cephalosporin derivatives
GB8821797D0 (en) * 1988-09-16 1988-10-19 Beecham Group Plc Novel compounds

Also Published As

Publication number Publication date
US5246926A (en) 1993-09-21
JPH02286680A (ja) 1990-11-26
DE69032681T2 (de) 1999-02-25
EP0395219A2 (fr) 1990-10-31
ES2121745T3 (es) 1998-12-16
CA2013391A1 (fr) 1990-09-30
DE69032681D1 (de) 1998-11-05
EP0395219B1 (fr) 1998-09-30
AU5232190A (en) 1990-10-04
EP0395219A3 (fr) 1992-04-01
DK0395219T3 (da) 1999-02-15
JP2979235B2 (ja) 1999-11-15
PT93602A (pt) 1990-11-20
KR900014403A (ko) 1990-10-23
AU625844B2 (en) 1992-07-16
ATE171705T1 (de) 1998-10-15

Similar Documents

Publication Publication Date Title
ZA902378B (en) Cephalos porins and their homologues process for their preparation and pharmaceutical compositions
HU906402D0 (en) Process for producing tricyclic carbapeneme derivatives an pharmaceutical preparatives containing these compounds as active substance
HU9702474D0 (en) Vinyl-pirrolidinone cephalosporins with basic substituents
EP0255908A3 (en) 7-ûû3-(aminomethyl)-3-alkyl¨-1-pyrrolidinyl¨-quinoline-carboxylic acid-derivatives and pharmaceutical compositions containing them
EP0335297A3 (fr) Dérivés de céphalosporine
AU1507888A (en) New bicyclic compounds, processes for preparation thereof and pharmaceutical composition comprising the same
EP0359536A3 (fr) Dérivés de céphalosporine, leur procédé de préparation et compositions pharmaceutiques
HUT57694A (en) Process for producing new beta-diketones and pharmaceutical compositions comprising same
HU901570D0 (en) Process for the preparation of azetidinyl-pyridonecarboxylic acid derivatives and pharmaceutical compositions containing such compounds
HUT60275A (en) Process for producing 7-acyl-3-(substituted carbamoyloxy)-cef-3-em-4-carboxylic acid derivatives and pharmaceutical compositions comprising such compounds
AU608643B2 (en) Novel derivatives of the oxime of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde, the process for their preparation, their use as medicaments and the compositions containing them
ES8506731A1 (es) Un procedimiento para preparar derivados de cefalosporina
AU636178B2 (en) 7 (alanylaminothiazol-iminoacetamide) substituted cephalosporin derivatives
ATE212637T1 (de) Anitbiotisch wirksame cephalosporine und verfahren zu ihrer herstellung
HK1003573A1 (en) New antibiotics of the mureidomycin group their preparation and their therapeutic use
EP0354757A3 (fr) Céphalosporines et produits homologues, leur procédé de préparation et compositions pharmaceutiques les contenant
GR3015422T3 (en) Thiadiazolylacetamide cephem derivatives.