DE69032681D1 - Cephalosporine und ihre Homologen, Verfahren zu ihrer Herstellung und pharmazeutische Präparate - Google Patents
Cephalosporine und ihre Homologen, Verfahren zu ihrer Herstellung und pharmazeutische PräparateInfo
- Publication number
- DE69032681D1 DE69032681D1 DE69032681T DE69032681T DE69032681D1 DE 69032681 D1 DE69032681 D1 DE 69032681D1 DE 69032681 T DE69032681 T DE 69032681T DE 69032681 T DE69032681 T DE 69032681T DE 69032681 D1 DE69032681 D1 DE 69032681D1
- Authority
- DE
- Germany
- Prior art keywords
- processes
- preparation
- optionally
- cephalosporins
- homologues
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898907171A GB8907171D0 (en) | 1989-03-30 | 1989-03-30 | Novel compounds |
GB898920791A GB8920791D0 (en) | 1989-09-14 | 1989-09-14 | Novel compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69032681D1 true DE69032681D1 (de) | 1998-11-05 |
DE69032681T2 DE69032681T2 (de) | 1999-02-25 |
Family
ID=26295148
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69032681T Expired - Fee Related DE69032681T2 (de) | 1989-03-30 | 1990-03-26 | Cephalosporine und ihre Homologen, Verfahren zu ihrer Herstellung und pharmazeutische Präparate |
Country Status (12)
Country | Link |
---|---|
US (1) | US5246926A (de) |
EP (1) | EP0395219B1 (de) |
JP (1) | JP2979235B2 (de) |
KR (1) | KR900014403A (de) |
AT (1) | ATE171705T1 (de) |
AU (1) | AU625844B2 (de) |
CA (1) | CA2013391A1 (de) |
DE (1) | DE69032681T2 (de) |
DK (1) | DK0395219T3 (de) |
ES (1) | ES2121745T3 (de) |
PT (1) | PT93602A (de) |
ZA (1) | ZA902378B (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0432042B1 (de) * | 1989-12-07 | 1996-08-28 | Meiji Seika Kaisha Ltd. | Cephalosporinderivate, ihre Herstellung und Anwendungen |
US6020329A (en) * | 1990-07-24 | 2000-02-01 | Pzifer Inc. | Cephaloporins and homologues, preparations and pharmaceutical compositions |
MY106399A (en) * | 1990-07-24 | 1995-05-30 | Pfizer | Cephalosporins and homologeus, preparation and pharmaceutical composition |
US6001997A (en) * | 1990-07-24 | 1999-12-14 | Bateson; John Hargreaves | Cephalosporins and homologues, preparations and pharmaceutical compositions |
GB9019743D0 (en) * | 1990-09-10 | 1990-10-24 | Beecham Group Plc | Novel compounds |
DE4037841A1 (de) * | 1990-11-28 | 1992-06-04 | Bayer Ag | Neue 3-substituierte cephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
IT1251643B (it) * | 1991-10-29 | 1995-05-17 | Mini Ricerca Scient Tecnolog | Derivati maleimmidici contenenti residui acrilici |
GB9125645D0 (en) * | 1991-12-03 | 1992-01-29 | Smithkline Beecham Plc | Novel compounds |
US5302711A (en) * | 1992-02-18 | 1994-04-12 | Eli Lilly And Company | Ester cleavage process for use with β-lactams |
GB9212609D0 (en) * | 1992-06-13 | 1992-07-29 | Smithkline Beecham Plc | Novel compounds |
GB9213567D0 (en) * | 1992-06-26 | 1992-08-12 | Smithkline Beecham Plc | Novel compounds |
US5604222A (en) | 1993-12-27 | 1997-02-18 | Lupin Laboratories, Ltd. | Method for the preparation of 2-chloro sulfinyl azetidinones |
US5578721A (en) | 1994-07-11 | 1996-11-26 | Lupin Laboratories Limited | Process for preparation of 3-exomethylene cepham sulfoxide esters |
GB9424847D0 (en) * | 1994-12-09 | 1995-02-08 | Smithkline Beecham Plc | Novel process |
IT1277048B1 (it) * | 1995-12-06 | 1997-11-04 | 3 Exo S R L | Procedimento per la preparazione di cefalosporine attraverso ciclizzazione riduttiva dicarbonilica per trattamento con |
WO2003053522A1 (en) * | 2001-12-21 | 2003-07-03 | Pfizer Products Inc. | Methods of treating bacterial infections in dogs and cats |
US20040002600A1 (en) * | 2002-06-20 | 2004-01-01 | Orchid Chemicals And Pharmaceuticals Limited | Process for the conversion of penam ring system to cepham ring system |
KR101599560B1 (ko) * | 2007-09-21 | 2016-03-03 | 아스트라제네카 아베 | 비경구 투여에 적합한 세펨 유도체를 함유하는 가용성 제형 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4868173A (en) * | 1984-11-20 | 1989-09-19 | Ici Pharma | Cephalosporin derivatives |
GB8821797D0 (en) * | 1988-09-16 | 1988-10-19 | Beecham Group Plc | Novel compounds |
-
1990
- 1990-03-26 DE DE69032681T patent/DE69032681T2/de not_active Expired - Fee Related
- 1990-03-26 EP EP90303177A patent/EP0395219B1/de not_active Expired - Lifetime
- 1990-03-26 DK DK90303177T patent/DK0395219T3/da active
- 1990-03-26 AT AT90303177T patent/ATE171705T1/de not_active IP Right Cessation
- 1990-03-26 ES ES90303177T patent/ES2121745T3/es not_active Expired - Lifetime
- 1990-03-28 CA CA002013391A patent/CA2013391A1/en not_active Abandoned
- 1990-03-28 US US07/500,397 patent/US5246926A/en not_active Expired - Lifetime
- 1990-03-28 AU AU52321/90A patent/AU625844B2/en not_active Ceased
- 1990-03-28 ZA ZA902378A patent/ZA902378B/xx unknown
- 1990-03-29 PT PT93602A patent/PT93602A/pt not_active Application Discontinuation
- 1990-03-29 KR KR1019900004244A patent/KR900014403A/ko not_active Application Discontinuation
- 1990-03-30 JP JP2081481A patent/JP2979235B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2013391A1 (en) | 1990-09-30 |
EP0395219A3 (de) | 1992-04-01 |
AU5232190A (en) | 1990-10-04 |
US5246926A (en) | 1993-09-21 |
ZA902378B (en) | 1991-06-26 |
JPH02286680A (ja) | 1990-11-26 |
DK0395219T3 (da) | 1999-02-15 |
JP2979235B2 (ja) | 1999-11-15 |
EP0395219A2 (de) | 1990-10-31 |
ES2121745T3 (es) | 1998-12-16 |
ATE171705T1 (de) | 1998-10-15 |
DE69032681T2 (de) | 1999-02-25 |
PT93602A (pt) | 1990-11-20 |
KR900014403A (ko) | 1990-10-23 |
AU625844B2 (en) | 1992-07-16 |
EP0395219B1 (de) | 1998-09-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69032681T2 (de) | Cephalosporine und ihre Homologen, Verfahren zu ihrer Herstellung und pharmazeutische Präparate | |
HU906402D0 (en) | Process for producing tricyclic carbapeneme derivatives an pharmaceutical preparatives containing these compounds as active substance | |
DE3750443T2 (de) | Cephalosporinverbindungen, Verfahren zu ihrer Herstellung und antibakterielle Mittel. | |
ATE37882T1 (de) | Cephalosporinverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate. | |
ATE220402T1 (de) | Basisch substituierte vinylpyrrolidin- cephalosporine | |
DE2963720D1 (en) | Cephalosporin derivatives, their preparation and the corresponding pharmaceutical compositions | |
EP0359536A3 (de) | Cephalosporinderivate, Verfahren zu ihrer Herstellung und pharmazeutische Präparate | |
ATE113953T1 (de) | Cephalosporine, verfahren zu ihrer herstellung und pharmazeutische präparate. | |
ATE87313T1 (de) | Cephemverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate. | |
ATE130299T1 (de) | Cephalosporinverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische präparate. | |
ES8800236A1 (es) | Un procedimiento para obtener acido-7-amino-3-propenilcefalosporanico y sus esteres. | |
AU556922B2 (en) | Pyridobenzodiazepinone derivatives | |
IL113744A0 (en) | 3-Cephem derivatives and their preparation | |
DE69217613D1 (de) | Stickstoff enthaltende bizyklische Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen | |
ES442217A1 (es) | Procedimiento para la obtencion de derivados cefem. | |
ATE32724T1 (de) | Cephalosporinverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate. | |
EP0354757A3 (de) | Cephalosporine und homologe Verbindungen, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate | |
ATE114313T1 (de) | Cephalosporine, verfahren zu ihrer herstellung, zwischenverbindungen und pharmazeutische präparate. | |
PT83712A (de) | Cephalosporinderivate und verfahren zu ihrer herstellung | |
DE3772936D1 (de) | Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate. | |
ATE143963T1 (de) | Cephalosporinderivate und verfahren zu ihrer herstellung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |