ZA902357B - Preservative system for ophthalmic formulations - Google Patents

Preservative system for ophthalmic formulations

Info

Publication number
ZA902357B
ZA902357B ZA902357A ZA902357A ZA902357B ZA 902357 B ZA902357 B ZA 902357B ZA 902357 A ZA902357 A ZA 902357A ZA 902357 A ZA902357 A ZA 902357A ZA 902357 B ZA902357 B ZA 902357B
Authority
ZA
South Africa
Prior art keywords
ophthalmic formulations
preservative system
preservative
ophthalmic
formulations
Prior art date
Application number
ZA902357A
Other languages
English (en)
Inventor
Cherng-Chyi Roger Fu
Roger Fu Cherng-Chyi
Deborah Marilyn Lidgate
Marilyn Lidgate Deborah
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of ZA902357B publication Critical patent/ZA902357B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
ZA902357A 1989-03-28 1990-03-27 Preservative system for ophthalmic formulations ZA902357B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/329,451 US5414011A (en) 1987-09-11 1989-03-28 Preservative system for ophthalmic formulations

Publications (1)

Publication Number Publication Date
ZA902357B true ZA902357B (en) 1991-11-27

Family

ID=23285465

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA902357A ZA902357B (en) 1989-03-28 1990-03-27 Preservative system for ophthalmic formulations

Country Status (8)

Country Link
US (1) US5414011A (fr)
EP (1) EP0390071A1 (fr)
JP (1) JP2954642B2 (fr)
KR (1) KR0184864B1 (fr)
AU (1) AU631849B2 (fr)
CA (1) CA2013188C (fr)
NZ (1) NZ233101A (fr)
ZA (1) ZA902357B (fr)

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IT1250691B (it) * 1991-07-22 1995-04-21 Giancarlo Santus Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac.
ES2079994B1 (es) * 1992-10-07 1996-08-01 Cusi Lab Formulacion farmaceutica a base de polimixina-trimetoprim y un agente antiinflamatorio para su utilizacion topica oftalmica y otica.
US5474985A (en) * 1993-12-22 1995-12-12 The Regents Of The University Of California Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors
FI951190A (fi) * 1994-03-15 1995-09-16 Senju Pharma Co Menetelmä pranoprofeenin stabilisoimiseksi ja pranoprofeenin stabiili nestemäinen valmiste
ES2079320B1 (es) * 1994-05-17 1996-10-16 Cusi Lab Disolucion oftalmica a base de un diclofenaco y tobramicina y sus aplicaciones.
AU3609795A (en) * 1994-10-10 1996-05-02 Novartis Ag Ophthalmic and aural compositions containing diclofenac potassium
JP3170619B2 (ja) * 1995-04-20 2001-05-28 参天製薬株式会社 有機アミンを配合したプラノプロフェン点眼液
US5674888A (en) * 1995-06-07 1997-10-07 University Of California Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
US5599535A (en) * 1995-06-07 1997-02-04 Regents Of The University Of California Methods for the cyto-protection of the trabecular meshwork
JPH09278653A (ja) * 1996-04-05 1997-10-28 Santen Pharmaceut Co Ltd 網膜疾患治療剤
US5980928A (en) * 1997-07-29 1999-11-09 Terry; Paul B. Implant for preventing conjunctivitis in cattle
US6552020B1 (en) 1999-07-30 2003-04-22 Allergan, Inc. Compositions including antibiotics and methods for using same
US6166012A (en) 1999-07-30 2000-12-26 Allergan Sales, Inc. Antibiotic compositions and method for using same
WO2001037838A1 (fr) * 1999-11-24 2001-05-31 Wakamoto Pharmaceutical Co., Ltd. Preparation aqueuse ophtalmique
US20020035107A1 (en) * 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
DE10161077A1 (de) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
US7166641B2 (en) * 2002-10-02 2007-01-23 Yung Shin Pharmaceutical Industrial Co., Ltd. Pharmaceutically acceptable salts containing local anesthetic and anti-inflammatory activities and methods for preparing the same
US8992980B2 (en) * 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
US8129431B2 (en) 2003-01-21 2012-03-06 Senju Pharmaceutical Co., Ltd. Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid
US8008338B2 (en) 2003-06-03 2011-08-30 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
DK1654002T4 (da) 2003-08-07 2014-02-17 Allergan Inc Sammensætninger til fremføring af terapeutiske midler til øjnene
PL1683526T3 (pl) * 2003-11-14 2012-09-28 Senju Pharma Co Preparat wodnego roztworu zawierający antybiotyk aminoglikozydowy i bromfenak
WO2005049014A1 (fr) * 2003-11-18 2005-06-02 Pharmacia Corporation Methodes de traitement ou de prevention de troubles oculaires lies au diabete par des inhibiteurs cox-2 seuls ou en association avec des agents anti-diabete classiques
EP1568369A1 (fr) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Utilisation du meloxicam pour le traitement de maladies respiratoires des porcs
ES2245611B1 (es) * 2004-06-29 2007-03-16 Laboratorio Reig Jofre, S.A. Composicion farmaceutica para uso ototopico.
CN1981869B (zh) * 2005-12-14 2011-04-06 信谊药厂 含普拉洛芬的复方非载体抗菌眼用制剂及其制备方法
EP2016936B1 (fr) * 2007-07-09 2010-09-15 Novagali Pharma S.A. Émulsion huile dans eau comprenant AINS et halogénure d'ammonium quaternaire
WO2009007409A2 (fr) * 2007-07-09 2009-01-15 Novagali Pharma Sa Emulsion d'huile dans l'eau comprenant des ains et des halogénures d'ammonium quaternaire
US8512687B2 (en) 2007-07-09 2013-08-20 Novagali Pharma Sa Oil in water emulsion comprising NSAIDs and quaternary ammonium halides
CA2701482C (fr) * 2007-10-08 2018-10-23 Lux Biosciences, Inc. Compositions ophtalmiques comprenant des inhibiteurs de la calcineurine ou des inhibiteurs de mtor
EP2211835A1 (fr) * 2007-11-27 2010-08-04 Alcon Research, Ltd. Formulations de solutions topiques ophtalmiques ou otiques contenant du chlorhydrate de moxifloxacine et du phosphate de dexaméthasone
US9192571B2 (en) * 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
US7842714B2 (en) * 2008-03-03 2010-11-30 Allergan, Inc. Ketorolac tromethamine compositions for treating ocular pain
AU2009249369A1 (en) * 2008-05-19 2009-11-26 Alcon Research, Ltd. Pharmaceutical compositions having carboxyvinyl polymer and povidone polymer
CN104189911A (zh) * 2008-06-12 2014-12-10 前瞻生物治疗公司 眼科组合物中的防腐剂替代物聚维酮碘
ES2537385T3 (es) * 2009-06-09 2015-06-08 Aurinia Pharmaceuticals Inc. Sistemas de suministro tópico para uso oftálmico
AU2010307096B2 (en) * 2009-10-12 2014-07-03 Boehringer Ingelheim Vetmedica Gmbh Containers for compositions comprising meloxicam
AU2010347598B2 (en) 2010-03-03 2014-11-27 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
WO2012099142A1 (fr) 2011-01-18 2012-07-26 千寿製薬株式会社 Composition liquide aqueuse de bromfénac qui est efficace comme conservateur
JP2013082682A (ja) * 2011-09-29 2013-05-09 Senju Pharmaceut Co Ltd 亜塩素酸塩を含有する水性製剤
EP2952190B1 (fr) * 2013-01-31 2017-09-06 Senju Pharmaceutical Co., Ltd. Solution aqueuse stable
US20190224275A1 (en) 2017-05-12 2019-07-25 Aurinia Pharmaceuticals Inc. Protocol for treatment of lupus nephritis
US20200170998A1 (en) * 2018-11-29 2020-06-04 Cellula Llc Umbilical cord blood serum and umbilical cord blood plasma preparation in combination with a nonsteroidal anti-inflammatory drug and freeze-drying the composition
CN115337264A (zh) * 2022-09-26 2022-11-15 福建师范大学 一种改进增效的妥布霉素滴眼液及制备方法

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US4087539A (en) * 1976-07-14 1978-05-02 Syntex (U.S.A.) Inc. 5-(2-Furoyl)-, 5-(2-thenoyl)-, 5-(3-furoyl)- and 5-(3-thenoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
US4089969A (en) * 1976-07-14 1978-05-16 Syntex (U.S.A.) Inc. 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
US4087538A (en) * 1976-09-09 1978-05-02 Merck & Co., Inc. Ophthalmic suspensions
US4097579A (en) * 1977-03-31 1978-06-27 Syntex (U.S.A.) Inc. 5-(2-Pyrroyl)-1,2-dihydro-3H-pyrrolo 1,2-a!pyrrole-1-carboxylic acid derivatives and process for the production thereof
CA1118792A (fr) * 1977-12-22 1982-02-23 Douglas L. Swallow Derives du tetracyclononane
US4230724A (en) * 1979-07-16 1980-10-28 Allergan Pharmaceuticals, Inc. Method of treating vascularization of the eye with Flurbiprofen
US4232038A (en) * 1979-08-31 1980-11-04 Syntex (U.S.A.) Inc. 5-Alkylsulfinylbenzoyl- and 5-alkylsulfonylbenzoyl-1,2-dihydro-3H-pyrrolo[1,]pyrrole-1-carboxylic acids
NZ196700A (en) * 1980-04-18 1983-04-12 Smith & Nephew Ass Anti-inflammatory compositions containing 5-benzoyl-1-methylpyrrole-2-acetic acid derivatives
US4336151A (en) * 1981-07-06 1982-06-22 American Cyanamid Company Disinfectant/cleanser compositions exhibiting reduced eye irritancy potential
US4336152A (en) * 1981-07-06 1982-06-22 American Cyanamid Company Disinfectant/cleanser compositions exhibiting reduced eye irritancy potential
JPS58126810A (ja) * 1981-12-24 1983-07-28 Kaken Pharmaceut Co Ltd 抗炎症眼科用液剤およびその製法
US4559343A (en) * 1982-09-07 1985-12-17 Alcon Laboratories, Inc. Nonirritating aqueous ophthalmic compositions comfort formulation for ocular therapeutic agents
US4500538A (en) * 1983-03-14 1985-02-19 Merck & Co., Inc. Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure
US4474751A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
JPS6023318A (ja) * 1983-07-19 1985-02-05 Lion Corp 点眼液
JPS60184013A (ja) * 1984-03-01 1985-09-19 Yoshitomi Pharmaceut Ind Ltd 点眼剤
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Also Published As

Publication number Publication date
KR0184864B1 (ko) 1999-05-01
CA2013188A1 (fr) 1990-09-28
AU5220190A (en) 1990-10-11
NZ233101A (en) 1992-10-28
JP2954642B2 (ja) 1999-09-27
EP0390071A1 (fr) 1990-10-03
AU631849B2 (en) 1992-12-10
JPH02286627A (ja) 1990-11-26
CA2013188C (fr) 2000-03-14
US5414011A (en) 1995-05-09
KR900013951A (ko) 1990-10-22

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